Results 31 to 40 of about 11,665,453 (372)
Pfam: The protein families database in 2021
Nucleic Acids Res., 2020 The Pfam database is a widely used resource for classifying protein sequences into families and domains. Since Pfam was last described in this journal, over 350 new families have been added in Pfam 33.1 and numerous improvements have been made to ...
Jaina Mistry +11 more
semanticscholar +1 more source
Protein complex prediction with AlphaFold-Multimer
bioRxiv, 2021 While the vast majority of well-structured single protein chains can now be predicted to high accuracy due to the recent AlphaFold [1] model, the prediction of multi-chain protein complexes remains a challenge in many cases.
Richard Evans +21 more
semanticscholar +1 more source
Binding of anisotropic curvature-inducing proteins onto membrane tubes [PDF]
Soft Matter 18, 3384-3394 (2022), 2022 Bin/Amphiphysin/Rvs superfamily proteins and other curvature-inducing proteins have anisotropic shapes and anisotropically bend biomembrane. Here, we report how the anisotropic proteins bind the membrane tube and are orientationally ordered using mean-field theory including an orientation-dependent excluded volume.
arxiv +1 more source
Nucleic Acids Res., 2016 A system-wide understanding of cellular function requires knowledge of all functional interactions between the expressed proteins. The STRING database aims to collect and integrate this information, by consolidating known and predicted protein–protein ...
Damian Szklarczyk +11 more
semanticscholar +1 more source
Nucleic Acids Res., 2021 The AlphaFold Protein Structure Database (AlphaFold DB, https://alphafold.ebi.ac.uk) is an openly accessible, extensive database of high-accuracy protein-structure predictions.
M. Váradi +26 more
semanticscholar +1 more source
Bacteriophage Protein–Protein Interactions [PDF]
, 2012 Bacteriophages T7, λ, P22, and P2/P4 (from Escherichia coli), as well as ϕ29 (from Bacillus subtilis), are among the best-studied bacterial viruses. This chapter summarizes published protein interaction data of intraviral protein interactions, as well as known phage-host protein interactions of these phages retrieved from the literature. We also review
Roman Häuser +9 more
openaire +5 more sources
Curvature sensing of curvature-inducing proteins with internal structure [PDF]
Phys. Rev. E 109, 024403 (2024), 2023 Many types of peripheral and transmembrane proteins can sense and generate membrane curvature. Laterally isotropic proteins and crescent proteins with twofold rotational symmetry, such as Bin/Amphiphysin/Rvs superfamily proteins, have been studied theoretically. However, proteins often have an asymmetric structure or a higher rotational symmetry.
arxiv +1 more source
UniProt: a worldwide hub of protein knowledge
Nucleic Acids Res., 2018 The UniProt Knowledgebase is a collection of sequences and annotations for over 120 million proteins across all branches of life. Detailed annotations extracted from the literature by expert curators have been collected for over half a million of these ...
Tunca Dogan
semanticscholar +1 more source
A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing
Nature, 2020 A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has infected over 2.3 million people, led to the death of more than 160,000 individuals
D. Gordon +124 more
semanticscholar +1 more source
Analysis of protein-coding genetic variation in 60,706 humans
Nature, 2015 Large-scale reference data sets of human genetic variation are critical for the medical and functional interpretation of DNA sequence changes. Here we describe the aggregation and analysis of high-quality exome (protein-coding region) DNA sequence data ...
James Y. Zou
semanticscholar +1 more source