Results 71 to 80 of about 15,507,347 (338)

Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling

open access: yesCell Communication and Signaling, 2023
Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute complex signaling hubs that are crucial for the development and homeostasis of the human body.
Aleksandra Gedaj   +9 more
doaj   +1 more source

Structure of cyanobacterial photosystem I complexed with ferredoxin at 1.97 Å resolution

open access: yesCommunications Biology, 2022
In order to aid the understanding of the electron transfer process within the cyanobacterial photosystem I, its structure - when complexed with Ferredoxin - is determined at 1.97 Å resolution.
Jiannan Li   +10 more
doaj   +1 more source

On combinatorial optimisation in analysis of protein-protein interaction and protein folding networks [PDF]

open access: yes, 2016
: Protein-protein interaction networks and protein folding networks represent prominent research topics at the intersection of bioinformatics and network science.
Chalupa, David
core   +1 more source

Modulators of Protein–Protein Interactions [PDF]

open access: yesChemical Reviews, 2014
No ...
Lech-Gustav Milroy   +4 more
openaire   +4 more sources

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

open access: yesNucleic Acids Research, 1997
The BLAST programs are widely used tools for searching protein and DNA databases for sequence similarities. For protein comparisons, a variety of definitional, algorithmic and statistical refinements described here permits the execution time of the BLAST
S. Altschul   +6 more
semanticscholar   +1 more source

Predicting Antibody Developability Profiles Through Early Stage Discovery Screening

open access: yesmAbs, 2020
Monoclonal antibodies play an increasingly important role for the development of new drugs across multiple therapy areas. The term ‘developability’ encompasses the feasibility of molecules to successfully progress from discovery to development via ...
Marc Bailly   +21 more
doaj   +1 more source

A constant domain mutation in a patient-derived antibody light chain reveals principles of AL amyloidosis

open access: yesCommunications Biology, 2023
Biophysical approaches reveal how a mutation in the constant light chain domain of a patient-derived antibody destabilizes the constant domain, prevents the dimerization of the light chain, and makes it more prone to proteolytic cleavage, unleashing the ...
Georg J. Rottenaicher   +4 more
doaj   +1 more source

Protein search for multiple targets on DNA [PDF]

open access: yes, 2015
Protein-DNA interactions are crucial for all biological processes. One of the most important fundamental aspects of these interactions is the process of protein searching and recognizing specific binding sites on DNA.
Alberts B.   +5 more
core   +2 more sources

STRING v10: protein–protein interaction networks, integrated over the tree of life

open access: yesNucleic Acids Res., 2014
The many functional partnerships and interactions that occur between proteins are at the core of cellular processing and their systematic characterization helps to provide context in molecular systems biology.
Damian Szklarczyk   +13 more
semanticscholar   +1 more source

Effects of chronic browsing on life‐history traits of an irruptive large herbivore population

open access: yesPopulation Ecology, EarlyView.
This study aimed to determine the relationship between diet quality, body mass, and size (hind foot length), and female reproduction and sought to identify the mechanism by which high density under severe food limitations is maintained. Our results demonstrated that sika deer introduced to Nakanoshima Island have maintained high densities through high ...
Koichi Kaji   +9 more
wiley   +1 more source

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