Results 181 to 190 of about 496,683 (293)
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi+10 more
wiley +1 more source
Anti-RPL30 as a novel biomarker for enhanced diagnosis of autoantibody-negative primary biliary cholangitis. [PDF]
Zeng ZY+8 more
europepmc +1 more source
Immunosuppressive Cytokine‐Tethered Hydrogel for Treating Rheumatoid Arthritis
An injectable hydrogel is developed by chemically tethering IL‐4, an immunosuppressive cytokine, to a hyaluronic acid‐based backbone. The hydrogel reduces joint friction and exerts immunomodulatory effects. In a rheumatoid arthritis (RA) mouse model, it reduced inflammation, preserved cartilage, and promoted anti‐inflammatory immune responses.
Woojin Back+3 more
wiley +1 more source
A motif-based analysis of glycan array data to determine the specificities of glycan-binding proteins [PDF]
Andrew P. Porter+5 more
openalex +1 more source
Electronic biosensor arrays for label-free DNA and protein analysis
Claudio, Stagni degli Esposti
openaire +2 more sources
Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan+13 more
wiley +1 more source
UMPlex™: a targeted next-generation sequencing primer design workflow. [PDF]
Lin D+11 more
europepmc +1 more source
Human Skin Models in Biophotonics: Materials, Methods, and Applications
This review discusses how the optical properties of human skin can be replicated in human skin models. It describes the principles, materials, and techniques used to develop artificial skin for biophotonics research. Finally, the article highlights recent advances and shows how these models improve the study of light‐skin interactions without the need ...
Dardan Bajrami+4 more
wiley +1 more source
Host cellular transcriptional response to respiratory syncytial virus infection in HEp-2 cells: insights from cDNA microarray and quantitative PCR analyses. [PDF]
Pastey MK, Lupfer C.
europepmc +1 more source