Rap1-mediated steric hindrance protects telomeres from MRX sensing. [PDF]
Mattarocci S +16 more
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ATG7 vs. ATG5: Distinct autophagy pathways shaping TGF-β signaling and endothelial function. [PDF]
Singh A +4 more
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Sex as a biological variable in human dental pulp stem cells: An exploratory epigenomic and transcriptomic comparison. [PDF]
Yamada S +6 more
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Screening Epitopes Through Comparative Analysis of Children and Mice Immune Responses to Pertussis Toxin Subunits (S1-S5) Induced by Whole-Cell Pertussis Vaccination. [PDF]
De-Simone SG +7 more
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Seventy-nine cytokines, chemokines, and growth factors were measured by protein array analysis in the cerebrospinal fluid of patients with meningitis and controls. Several factors were found to be regulated, which have not been studied in the CNS before, e.g., macrophage inflammatory protein-1delta (CCL15) and neutrophil-activating peptide-2 (CXCL7 ...
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MULTIPLEXED PROTEIN ARRAY PLATFORMS FOR ANALYSIS OF AUTOIMMUNE DISEASES
Annual Review of Immunology, 2006Several proteomics platforms have emerged in the past decade that show great promise for filling in the many gaps that remain from earlier studies of the genome and from the sequencing of the human genome itself. This review describes applications of proteomics technologies to the study of autoimmune diseases.
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Single-Molecule Arrays for Protein and Nucleic Acid Analysis
Annual Review of Analytical Chemistry, 2017The last few years have seen breakthroughs that will transform our ability to measure important analytes. Miniaturization of reaction volumes and confinement of analytes of interest into ultrasmall containers have greatly enhanced the sensitivity and throughput of many detection methods. Fabrication of microwell arrays and implementation of bead-based
Limor, Cohen, David R, Walt
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RPPApipe: A pipeline for the analysis of reverse-phase protein array data
Biosystems, 2014Today, web-based data analysis pipelines exist for a wide variety of microarray platforms, such as ordinary gene-centered arrays, exon arrays and SNP arrays. However, most of the available software tools provide only limited support for reverse-phase protein arrays (RPPA), as relevant inherent properties of the corresponding datasets are not taken into
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Vertical nanowire arrays as a versatile platform for protein detection and analysis
Nanoscale, 2013Protein microarrays are valuable tools for protein assays. Reducing spot sizes from micro- to nano-scale facilitates miniaturization of platforms and consequently decreased material consumption, but faces inherent challenges in the reduction of fluorescent signals and compatibility with complex solutions. Here we show that vertical arrays of nanowires (
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