Results 51 to 60 of about 25,768,908 (251)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System [PDF]

, 2018
Protein folding in the cell requires ATP-driven chaperone machines such as the conserved Hsp70 and Hsp90. It is enigmatic how these machines fold proteins.
Mayer, Matthias, Sub Cellular Protein Chemistry, Kityk, R., Rüdiger, S.G.D., Morán Luengo, T., Cellular Protein Chemistry   +5 more
core   +2 more sources

Investigation of Interactions between Two Monoclonal Antibodies and SARS Virus with a Label-Free Protein Array

, 2005
The investigation of interactions between two kinds of monoclonal antibodies and SARS virus with a label-free protein array technique were presented in this paper.
齐财, Chen YY(陈艳艳), Qi C(齐财), Jin G(靳刚), Wang ZH(王战会)   +4 more
core   +3 more sources

Data in support of proteomic analysis of pneumococcal pediatric clinical isolates to construct a protein array

Data in Brief, 2016
Surface proteins play key roles in the interaction between cells and their environment, and in pathogenic microorganisms they are the best targets for drug or vaccine discovery and/or development.
Alfonso Olaya-Abril, Ignacio Obando, Manuel J. Rodríguez-Ortega   +2 more
doaj   +1 more source

Identification of proteins associated with clinical and pathological features of proliferative diabetic retinopathy in vitreous and fibrovascular membranes. [PDF]

PLoS ONE, 2017
To identify the protein profiles in vitreous associated with retinal fibrosis, angiogenesis, and neurite formation in epiretinal fibrovascular membranes (FVMs) in patients with proliferative diabetic retinopathy (PDR).Vitreous samples of 5 non-diabetic ...
Ingeborg Klaassen, Ewout W de Vries, Ilse M C Vogels, Antoine H C van Kampen, Machteld I Bosscha, David H W Steel, Cornelis J F Van Noorden, Sarit Y Lesnik-Oberstein, Reinier O Schlingemann   +8 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

A Sensitive Multichannel Fluorescent Polymer Sensor Array for the Detection of Protein Fluctuations in Serum

Sensors
Serum contains diverse proteins whose concentrations vary with pathological conditions such as cancer, liver disease, neurological disorder, and infections.
Junwhee Yang, Colby Alves, Kanwal Nazir, Mingdi Jiang, Nicolas Araujo, Vincent M. Rotello   +5 more
doaj   +1 more source

KIAA0101 (OEACT-1), an expressionally down-regulated and growth-inhibitory gene in human hepatocellular carcinoma

BMC Cancer, 2006
Background Our previous cDNA array results indicated KIAA0101 as one of the differentially expressed genes in human hepatocellular carcinoma (HCC) as compared with non-cancerous liver.
Li Jinjun, Guo Minglei, Wan Dafang, Gu Jianren   +3 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Single-Cell Spatial MIST for Versatile, Scalable Detection of Protein Markers

Biosensors, 2023
High-multiplex detection of protein biomarkers across tissue regions has been an attractive spatial biology approach due to significant advantages over traditional immunohistochemistry (IHC) methods. Different from most methods, spatial multiplex in situ
Arafat Meah, Vadanasundari Vedarethinam, Robert Bronstein, Nehaben Gujarati, Tanya Jain, Sandeep K. Mallipattu, Yueming Li, Jun Wang   +7 more
doaj   +1 more source