Results 51 to 60 of about 583,434 (343)

Bioinformatics analysis of mitochondrial encephalomyopathy with lactic acidemia and stroke⁃like episodes geneome microarray based on GEO database

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To investigate the possible pathogenesis and clinical feature of mitochondrial encephalomyopathy with lactic acidemia and stroke ⁃ like episodes (MELAS) on the molecular level by bioinformatics analysis of differential expression genes. Methods
Qian XU, Yang GAO, Lei LI, Jun YAN, Li⁃ling WANG, Tao⁃jie REN   +5 more
doaj  

Proteomics, pathway array and signaling network-based medicine in cancer

Cell Division, 2009
Cancer is a multifaceted disease that results from dysregulated normal cellular signaling networks caused by genetic, genomic and epigenetic alterations at cell or tissue levels. Uncovering the underlying protein signaling network changes, including cell
Xu Hong, Liu Wei, Song Dong, Wu Josephine, Wang Libo, Wang Hongxia, Che Yufang, Zhao Xin, Liu Xiaoliang, Gao Ling, Ye Fei, Zhang David Y, Jiang Bo, Zhang Weijia, Wang Jinhua, Lee Peng   +15 more
doaj   +1 more source

Identifying differential exon splicing using linear models and correlation coefficients [PDF]

, 2009
Background: With the availability of the Affymetrix exon arrays a number of tools have been developed to enable the analysis. These however can be expensive or have several pre-installation requirements.
Pallas Jacqueline A, Shah, SH, Shah Sonia H, Sonia H Shah, Jacqueline A Pallas, Shah, Sonia H., Pallas, JA, Pallas, Jacqueline A.   +7 more
core   +1 more source

Processing of chlamydia abortus polymorphic membrane protein 18D during the chlamydial developmental cycle [PDF]

, 2012
<p>Background: Chlamydia possess a unique family of autotransporter proteins known as the Polymorphic membrane proteins (Pmps). While the total number of pmp genes varies between Chlamydia species, all encode a single pmpD gene.
Smith, David George Emslie, Michelle Sait (122019), Longbottom, D., David G E Smith, David G. E. Smith, Aitchison, Kevin, Neil F. Inglis (122039), Wheelhouse, NM, Sait, M, Longbottom, D, Livingstone, M., Nick M. Wheelhouse (122015), McLean, K., McLean, Kevin, Wright, F., Morag Livingstone, Aitchison, K., Frank Wright (122030), Wright, F, Michelle Sait, Neil F. Inglis, Kevin McLean (122035), Wright, Frank, Livingstone, Morag, Smith, David G E, Wheelhouse, Nick M, Smith, DGE, Wheelhouse, N.M., Nick M Wheelhouse, Morag Livingstone (122027), Inglis, N.F., David Longbottom, Longbottom, David, Neil F Inglis, Wheelhouse, Nick M., Inglis, Neil F, David Longbottom (122043), Kevin Aitchison (122024), Livingstone, M, Aitchison, K, Inglis, NF, Frank Wright, Sait, M., Kevin McLean, Nick M. Wheelhouse, David G. E. Smith (122041), Sait, Michelle, Inglis, Neil F., Kevin Aitchison, McLean, K, Smith, D.G.E.   +50 more
core   +1 more source

Noncoder : a web interface for exon array-based detection of long non-coding RNAs

, 2012
Due to recent technical developments, a high number of long non-coding RNAs (lncRNAs) have been discovered in mammals. Although it has been shown that lncRNAs are regulated differently among tissues and disease statuses, functions of these transcripts ...
Braun, Thomas, Uchida, Shizuka, Gellert, Pascal, Ponomareva, Yuliya   +3 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Sex differences in global mRNA content of human skeletal muscle. [PDF]

PLoS ONE, 2009
Women oxidize more fat as compared to men during endurance exercise and several groups have shown that the mRNA content of selected genes related to fat oxidation are higher in women (e.g.
Amy C Maher, Minghua H Fu, Robert J Isfort, Alex R Varbanov, Xiaoyan A Qu, Mark A Tarnopolsky   +5 more
doaj   +1 more source

A Metabolomics Investigation of the Metabolic Changes of Raji B Lymphoma Cells Undergoing Apoptosis Induced by Zinc Ions

Metabolites, 2021
Zinc plays a pivotal role in the function of cells and can induce apoptosis in various cancer cells, including Raji B lymphoma. However, the metabolic mechanism of Zn-induced apoptosis in Raji cells has not been explored.
Naeun Yoon, Hyunbeom Lee, Geonhee Lee, Eun Hye Kim, Seong Hwan Kim, Jeong-O Lee, Yunseon Song, Jinyoung Park, So-Dam Kim, Yeojin Kim, Byung Hwa Jung   +10 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Synthetic dosage lethal (SDL) interaction data of Hmt1 arginine methyltransferase

Data in Brief, 2020
The introduction of methyl groups on arginine residues is catalysed by Protein Arginine Methyltransferases (PRMTs). However, the regulatory mechanisms that dictate the levels of protein arginine methylation within cells are still not completely ...
Dimitris Kyriakou, Mamantia Constantinou, Antonis Kirmizis   +2 more
doaj   +1 more source