Results 41 to 50 of about 2,677,114 (323)

Predicting Deep Learning Based Multi-Omics Parallel Integration Survival Subtypes in Lung Cancer Using Reverse Phase Protein Array Data

Biomolecules, 2020
Mortality attributed to lung cancer accounts for a large fraction of cancer deaths worldwide. With increasing mortality figures, the accurate prediction of prognosis has become essential.
Satoshi Takahashi, Ken Asada, Ken Takasawa, Ryohei Shimoyama, Akira Sakai, Amina Bolatkan, Norio Shinkai, Kazuma Kobayashi, M. Komatsu, S. Kaneko, J. Sese, Ryuji Hamamoto   +11 more
semanticscholar   +1 more source

Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions [PDF]

, 2016
Babesia microti, a tick-transmitted, intraerythrocytic protozoan parasite circulating mainly among small mammals, is the primary cause of human babesiosis.
Ben Mamoun, Choukri, Brancato, Jana, Chibucos, Marcus, Colinge, Jacques, Cornillot, Emmanuel, Crabtree, Jonathan, Dwivedi, Ankit, Fraser, Claire M., Frutos, Roger, Gotia, Hanzel T., Hung, Chris, Ifeonu, Olukemi O., Krause, Peter J., Kumar, Vidya, Kumari, Priti, Lawres, Lauren, McCracken, Carrie, Molina, Douglas M., Orvis, Joshua, Ott, Sandy, Pablo, Jozelyn V., Pazzi, Joseph E., Reynes, Christelle, Sadzewicz, Lisa, Sengamalay, Naomi, Shetty, Amol C., Silva, Joana C., Su, Qi, Tallon, Luke, Tretina, Kyle, Usmani-Brown, Sahar, Virji, Azan Z.   +31 more
core   +3 more sources

Noncoder : a web interface for exon array-based detection of long non-coding RNAs [PDF]

, 2012
Due to recent technical developments, a high number of long non-coding RNAs (lncRNAs) have been discovered in mammals. Although it has been shown that lncRNAs are regulated differently among tissues and disease statuses, functions of these transcripts ...
Braun, Thomas, Gellert, Pascal, Ponomareva, Yuliya, Uchida, Shizuka   +3 more
core   +1 more source

Signal Transduction Protein Array Analysis Links LRRK2 to Ste20 Kinases and PKC Zeta That Modulate Neuronal Plasticity

PLoS ONE, 2010
Background Dominant mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, however, the underlying pathogenic mechanisms are poorly understood.
S. Zach, S. Felk, F. Gillardon
semanticscholar   +1 more source

Application of mRNA Arrays for the Production of mCherry Reporter-Protein Arrays for Quantitative Gene Expression Analysis [PDF]

ACS Synthetic Biology, 2019
The development of programmable regulators that precisely and predictably control gene expression is a major goal of synthetic biology. Consequently, rapid high-throughput biochemical methods capable of quantitatively analyzing all components of gene expression would be of value in the characterization and optimization of regulator performance. In this
Masoud Norouzi, Andrew R. Pickford, Louise E. Butt, Helen A. Vincent, Anastasia J. Callaghan   +4 more
openaire   +3 more sources

Role of insulin-like growth factor binding protein-3 in 1, 25-dihydroxyvitamin-d 3 -induced breast cancer cell apoptosis. [PDF]

, 2013
Insulin-like growth factor I (IGF-I) is implicated in breast cancer development and 1, 25-dihydroxyvitamin D3 (1, 25-D3) has been shown to attenuate prosurvival effects of IGF-I on breast cancer cells.
Brosseau, C, Colston, KW, Pirianov, G
core   +2 more sources

PMA: Protein Microarray Analyser, a user-friendly tool for data processing and normalization

BMC Research Notes, 2018
Objective Protein microarrays provide a high-throughput platform to measure protein interactions and associated functions, and can aid in the discovery of cancer biomarkers.
Jessica Da Gama Duarte, Ryan W. Goosen, Peter J. Lawry, Jonathan M. Blackburn   +3 more
doaj   +1 more source

A Novel Method to Identify Autoantibodies against Putative Target Proteins in Serum from beta-Thalassemia Major: A Pilot Study

Biomedicines, 2020
Abnormal immune reactivity in patients with beta-thalassemia (beta-thal) major can be associated with poor prognosis. Immunome protein-array analysis represents a powerful approach to identify novel biomarkers.
Afshan Sumera, Nur Diana Anuar, Ammu Kutty Radhakrishnan, Hishamshah Ibrahim, Nurul H. Rutt, Nur Hafiza Ismail, Ti-Myen Tan, Abdul Aziz Baba   +7 more
doaj   +1 more source

Monitoring of Serum Levels of Angiogenin, ENA-78 and GRO Chemokines in Patients with Renal Cell Carcinoma (RCC) in the Course of the Treatment

Acta Medica, 2008
Tumour progression requires the presence of a rich vascular supply. A number of cytokines, chemokines and proteases participate in the process of tumour angiogenesis.
Dagmar Hlávková, Otakar Kopecký, Šárka Lukešová, Vladimíra Vroblová, Ctirad Andrýs, Petr Morávek, Miroslav Podhola, Doris Vokurková, Hynek Šafránek   +8 more
doaj   +1 more source

YPIBP: A repository for phosphoinositide-binding proteins in yeast

Computational and Structural Biotechnology Journal, 2021
Phosphoinositides (PIs) are a family of eight lipids consisting of phosphatidylinositol (PtdIns) and its seven phosphorylated forms. PIs have important regulatory functions in the cell including lipid signaling, protein transport, and membrane ...
Jagat Rathod, Han-Chen Yen, Biqing Liang, Yan-Yuan Tseng, Chien-Sheng Chen, Wei-Sheng Wu   +5 more
doaj   +1 more source