Results 41 to 50 of about 583,434 (343)

High-throughput analysis and protein engineering using microcapillary arrays [PDF]

Nature Chemical Biology, 2015
We describe a multipurpose technology platform, termed μSCALE (microcapillary single-cell analysis and laser extraction), that enables massively parallel, quantitative biochemical and biophysical measurements on millions of protein variants expressed from yeast or bacteria.
Bob Chen, Sungwon Lim, Arvind Kannan, Spencer C Alford, Fanny Sunden, Daniel Herschlag, Ivan K Dimov, Thomas M Baer, Jennifer R Cochran   +8 more
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Array-Based Protein Sensing Using an Aggregation-Induced Emission (AIE) Light-Up Probe [PDF]

, 2018
Protein detection and identification are important for the diagnosis of diseases; however, the development of facile sensing probes still remains challenging.
Chaekyu Kim (1920268), Huyeon Choi (5067953), Sangpil Kim (5638892), Seungho Lee (827909), Ryu, Ja-Hyoung, Kim, Sangpil, Ja-Hyoung Ryu (1532641), Choi, Huyeon, Kim, Chaekyu, Lee, Seungho   +9 more
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Array Formatting of the Heat-Transfer Method (HTM) for the Detection of Small Organic Molecules by Molecularly Imprinted Polymers [PDF]

, 2014
In this work we present the first steps towards a molecularly imprinted polymer (MIP)-based biomimetic sensor array for the detection of small organic molecules via the heat-transfer method (HTM).
Peeters, Marloes, Van Grinsven B, Peeters, M, Cornelis, Peter, Kellens E, Peter Cornelis, Losada-Pérez, P, Peeters M, Wagner, Patrick Hermann, Wackers G, Ward De Ceuninck, De Ceuninck W, Bart van Grinsven, De Ceuninck, W, Ronald Thoelen, Thijs Vandenryt, Losada-Perez P, Peeters, Marloes; id_orcid, Vandenryt, T, Vandenryt T, Marloes Peeters, Cornelis P, Grinsven, Bart van, Thoelen R, Kellens, E, Kellens, Evelien, Ceuninck, Ward De, Wackers, Gideon, Patricia Losada-Pérez, Cornelis, P, Vandenryt, Thijs, Evelien Kellens, Wagner P, Wagner, P, Thoelen, Ronald, De Ceuninck, Ward, Van Grinsven, Bart, Gideon Wackers, Wackers, G, Thoelen, R, van Grinsven, B, Losada Perez, Patricia, Losada-Perez, Patricia, Patrick Wagner, Vanderyt, Thijs, Wagner, Patrick   +45 more
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A Network-based Analysis of Polyanion-binding Proteins Utilizing Yeast Protein Arrays [PDF]

Molecular & Cellular Proteomics, 2006
The high affinity of certain cellular polyanions for many proteins (polyanion-binding proteins (PABPs)) has been demonstrated previously. It has been hypothesized that such polyanions may be involved in protein structure stabilization, stimulation of folding through chaperone-like activity, and intra- and extracellular protein transport as well as ...
Salamat-Miller, N., Fang, J., Seidel, C., Smalter, A., Assenov, Y., Albrecht, M., Middaugh, C.   +6 more
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Cluster analysis of protein array results via similarity of Gene Ontology annotation

BMC Bioinformatics, 2006
Background With the advent of high-throughput proteomic experiments such as arrays of purified proteins comes the need to analyse sets of proteins as an ensemble, as opposed to the traditional one-protein-at-a-time approach.
Wolting Cheryl, McGlade C Jane, Tritchler David   +2 more
doaj   +1 more source

PMA: Protein Microarray Analyser, a user-friendly tool for data processing and normalization

BMC Research Notes, 2018
Objective Protein microarrays provide a high-throughput platform to measure protein interactions and associated functions, and can aid in the discovery of cancer biomarkers.
Jessica Da Gama Duarte, Ryan W. Goosen, Peter J. Lawry, Jonathan M. Blackburn   +3 more
doaj   +1 more source

A Novel Method to Identify Autoantibodies against Putative Target Proteins in Serum from beta-Thalassemia Major: A Pilot Study

Biomedicines, 2020
Abnormal immune reactivity in patients with beta-thalassemia (beta-thal) major can be associated with poor prognosis. Immunome protein-array analysis represents a powerful approach to identify novel biomarkers.
Afshan Sumera, Nur Diana Anuar, Ammu Kutty Radhakrishnan, Hishamshah Ibrahim, Nurul H. Rutt, Nur Hafiza Ismail, Ti-Myen Tan, Abdul Aziz Baba   +7 more
doaj   +1 more source

Monitoring of Serum Levels of Angiogenin, ENA-78 and GRO Chemokines in Patients with Renal Cell Carcinoma (RCC) in the Course of the Treatment

Acta Medica, 2008
Tumour progression requires the presence of a rich vascular supply. A number of cytokines, chemokines and proteases participate in the process of tumour angiogenesis.
Dagmar Hlávková, Otakar Kopecký, Šárka Lukešová, Vladimíra Vroblová, Ctirad Andrýs, Petr Morávek, Miroslav Podhola, Doris Vokurková, Hynek Šafránek   +8 more
doaj   +1 more source

YPIBP: A repository for phosphoinositide-binding proteins in yeast

Computational and Structural Biotechnology Journal, 2021
Phosphoinositides (PIs) are a family of eight lipids consisting of phosphatidylinositol (PtdIns) and its seven phosphorylated forms. PIs have important regulatory functions in the cell including lipid signaling, protein transport, and membrane ...
Jagat Rathod, Han-Chen Yen, Biqing Liang, Yan-Yuan Tseng, Chien-Sheng Chen, Wei-Sheng Wu   +5 more
doaj   +1 more source

Analysis of leukocyte membrane protein interactions using protein microarrays

, 2005
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
Foster-Cuevas, M, Letarte, Michelle, Deborah Hatherley, Foster-Cuevas, Mildred, Hatherley, D, Barclay, AN, Michelle Letarte, Saunders, Nigel, A Neil Barclay, Saunders, NJ, Hatherley, Deborah, Letarte, M, Barclay, Neil, Mildred Foster-Cuevas, Nigel J Saunders, Saunders, Nigel J, Voulgaraki, D, Despina Voulgaraki, Voulgaraki, Despina   +18 more
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