Results 21 to 30 of about 583,434 (343)

Sodium danshensu attenuates cerebral ischemia–reperfusion injury by targeting AKT1

open access: yesFrontiers in Pharmacology, 2022
The beneficial properties of Sodium Danshensu (SDSS) for controlling cerebral ischemia and reperfusion injury (CIRI) are elucidated here both in vivo and in vitro.
Qing Gao   +10 more
doaj   +1 more source

Proteomic applications of surface plasmon resonance biosensors: analysis of protein arrays [PDF]

open access: goldExperimental & Molecular Medicine, 2005
Proteomics is one of the most important issues in the post-genomic area, because it can greatly contribute to identifying protein biomarkers for disease diagnosis and drug screening. Protein array is a key technology for proteome researches and has been analyzed by various methods including fluorescence, mass spectrometry, atomic force microscopy and ...
Jong Seol Yuk, Kwon‐Soo Ha
openalex   +3 more sources

A Network-based Analysis of Polyanion-binding Proteins Utilizing Human Protein Arrays [PDF]

open access: hybridJournal of Biological Chemistry, 2007
The existence of interactions between many cellular proteins and various polyanionic surfaces within a cell is now well established. The functional role of such interactions, however, remains to be clearly defined. The existence of protein arrays, with a large selection of different kinds of proteins, provides a way to better address a number of ...
Nazila Salamat‐Miller   +5 more
openalex   +5 more sources

An Automated Approach to Assess Relative Galectin-Glycan Affinity Following Glycan Microarray Analysis

open access: yesFrontiers in Molecular Biosciences, 2022
Numerous studies have highlighted the utility of glycan microarray analysis for the elucidation of protein-glycan interactions. However, most current glycan microarray studies analyze glycan binding protein (GBP)-glycan interactions at a single protein ...
Alex D. Ho   +6 more
doaj   +1 more source

Smartphone-Based Quantitative Analysis of Protein Array Signals for Biomarker Detection in Lupus

open access: yesChemosensors, 2022
Fluorescence-based microarray offers great potential in clinical diagnostics due to its high-throughput capability, multiplex capabilities, and requirement for a minimal volume of precious clinical samples.
Guang Yang   +5 more
doaj   +1 more source

RPPanalyzer: Analysis of reverse-phase protein array data [PDF]

open access: yesBioinformatics, 2010
Abstract Summary: RPPanalyzer is a statistical tool developed to read reverse-phase protein array data, to perform the basic data analysis and to visualize the resulting biological information. The R-package provides different functions to compare protein expression levels of different samples and to normalize the data.
Mannsperger, Heiko A.   +4 more
openaire   +3 more sources

Antibody Protein Array Analysis of the Tear Film Cytokines [PDF]

open access: yesOptometry and Vision Science, 2008
ABSTRACT Purpose. Many bioactive proteins including cytokines are reported to increase in dry eye disease although the specific profile and concentration of inflammatory mediators varies considerably from study to study.
Shimin, Li   +7 more
openaire   +2 more sources

In situ structural analysis of Golgi intracisternal protein arrays [PDF]

open access: yesProceedings of the National Academy of Sciences, 2015
Significance To our knowledge, this is the first detailed study of Golgi ultrastructure within unperturbed cells. Three intracisternal structures were identified, with implications for Golgi architecture and trafficking: ( i ) Bundles of filaments show how cargoes may ...
Engel, Benjamin D.   +5 more
openaire   +4 more sources

Protein Array Based Interactome Analysis of Amyloid-β Indicates an Inhibition of Protein Translation

open access: greenJournal of Proteome Research, 2011
Oligomeric amyloid-β is currently of interest in amyloid-β mediated toxicity and the pathogenesis of Alzheimer's disease. Mapping the amyloid-β interaction partners could help to discover novel pathways in disease pathogenesis. To discover the amyloid-β interaction partners, we applied a protein array with more than 8100 unique recombinantly expressed ...
Dezső P. Virók   +9 more
openalex   +4 more sources

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