Results 21 to 30 of about 25,768,908 (251)

Protein and Peptide Array Analysis of Autoimmune Disease

BioTechniques, 2002
Molecular cloning, sequencing of the human genome, and other major advances in biomedical research have contributed substantially to our understanding of autoimmune disease.
William H. Robinson, Lawrence Steinman, Paul J. Utz   +2 more
doaj   +1 more source

Analysis of protein interaction and function with a 3-dimensional MALDI-MS protein array

BioTechniques, 2005
Protein profiling and characterization of protein interactions in biological samples ultimately require indicator-free methods of signal detection, which likewise offer an opportunity to distinguish specific interactions from nonspecific protein binding.
Igor M. Gavin, Alexander Kukhtin, David Glesne, Daniel Schabacker, Darrell P. Chandler   +4 more
doaj   +1 more source

Noncoder : a web interface for exon array-based detection of long non-coding RNAs [PDF]

, 2012
Due to recent technical developments, a high number of long non-coding RNAs (lncRNAs) have been discovered in mammals. Although it has been shown that lncRNAs are regulated differently among tissues and disease statuses, functions of these transcripts ...
Braun, Thomas, Uchida, Shizuka, Gellert, Pascal, Ponomareva, Yuliya   +3 more
core   +1 more source

Analysis of Disulfide Bond Formation [PDF]

, 2017
In this unit, protocols are provided for detection of disulfide bond formation in cultures of intact cells and in an in vitro translation system containing isolated microsomes or semi-permeabilized cells.
Sub Cellular Protein Chemistry, Ineke Braakman, Hebert, Daniel N., Lydia Lamriben, Guus van Zadelhoff, van Zadelhoff, Guus, Braakman, Ineke, Daniel N. Hebert, Lamriben, Lydia, Cellular Protein Chemistry   +9 more
core   +2 more sources

Cluster analysis of protein array results via similarity of Gene Ontology annotation

BMC Bioinformatics, 2006
Background With the advent of high-throughput proteomic experiments such as arrays of purified proteins comes the need to analyse sets of proteins as an ensemble, as opposed to the traditional one-protein-at-a-time approach.
Wolting Cheryl, McGlade C Jane, Tritchler David   +2 more
doaj   +1 more source

Array-Based Protein Sensing Using an Aggregation-Induced Emission (AIE) Light-Up Probe [PDF]

, 2018
Protein detection and identification are important for the diagnosis of diseases; however, the development of facile sensing probes still remains challenging.
Chaekyu Kim (1920268), Huyeon Choi (5067953), Sangpil Kim (5638892), Seungho Lee (827909), Ryu, Ja-Hyoung, Kim, Sangpil, Ja-Hyoung Ryu (1532641), Choi, Huyeon, Kim, Chaekyu, Lee, Seungho   +9 more
core   +1 more source

CHAPTER 1.1. Disulfide Bonds in Protein Folding and Stability [PDF]

, 2018
Disulfide bonds are unique among post-translational modifications, as they add covalent crosslinks to the polypeptide chain. Accordingly, they can exert pronounced effects on protein folding and stability. This is of particular importance for secreted or
Sub Cellular Protein Chemistry, Hendershot, Linda M., Feige, Matthias J., Ineke Braakman, Matthias J. Feige, Braakman, Ineke, Cellular Protein Chemistry, Linda M. Hendershot   +7 more
core   +1 more source

PMA: Protein Microarray Analyser, a user-friendly tool for data processing and normalization

BMC Research Notes, 2018
Objective Protein microarrays provide a high-throughput platform to measure protein interactions and associated functions, and can aid in the discovery of cancer biomarkers.
Jessica Da Gama Duarte, Ryan W. Goosen, Peter J. Lawry, Jonathan M. Blackburn   +3 more
doaj   +1 more source

A Novel Method to Identify Autoantibodies against Putative Target Proteins in Serum from beta-Thalassemia Major: A Pilot Study

Biomedicines, 2020
Abnormal immune reactivity in patients with beta-thalassemia (beta-thal) major can be associated with poor prognosis. Immunome protein-array analysis represents a powerful approach to identify novel biomarkers.
Afshan Sumera, Nur Diana Anuar, Ammu Kutty Radhakrishnan, Hishamshah Ibrahim, Nurul H. Rutt, Nur Hafiza Ismail, Ti-Myen Tan, Abdul Aziz Baba   +7 more
doaj   +1 more source

Array Formatting of the Heat-Transfer Method (HTM) for the Detection of Small Organic Molecules by Molecularly Imprinted Polymers [PDF]

, 2014
In this work we present the first steps towards a molecularly imprinted polymer (MIP)-based biomimetic sensor array for the detection of small organic molecules via the heat-transfer method (HTM).
Peeters, Marloes, Van Grinsven B, Peeters, M, Cornelis, Peter, Kellens E, Peter Cornelis, Losada-Pérez, P, Peeters M, Wagner, Patrick Hermann, Wackers G, Ward De Ceuninck, De Ceuninck W, Bart van Grinsven, De Ceuninck, W, Ronald Thoelen, Thijs Vandenryt, Losada-Perez P, Peeters, Marloes; id_orcid, Vandenryt, T, Vandenryt T, Marloes Peeters, Cornelis P, Grinsven, Bart van, Thoelen R, Kellens, E, Kellens, Evelien, Ceuninck, Ward De, Wackers, Gideon, Patricia Losada-Pérez, Cornelis, P, Vandenryt, Thijs, Evelien Kellens, Wagner P, Wagner, P, Thoelen, Ronald, De Ceuninck, Ward, Van Grinsven, Bart, Gideon Wackers, Wackers, G, Thoelen, R, van Grinsven, B, Losada Perez, Patricia, Losada-Perez, Patricia, Patrick Wagner, Vanderyt, Thijs, Wagner, Patrick   +45 more
core   +1 more source