Results 21 to 30 of about 574,007 (259)
BMC Cancer, 2023 Colorectal cancer (CRC) is the third most prevalent cancer in the world, yet the sensitivity and specificity of biomarkers for CRC diagnosis are insufficient.
Takahiro Arasawa +11 more
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BMC Genomics, 2023 Background Evident adolescent idiopathic scoliosis (AIS) incurs high treatment costs, low quality of life, and many complications. Early screening of AIS is essential to avoid progressing to an evident stage.
Zhenxuan Shao +8 more
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High-throughput analysis and protein engineering using microcapillary arrays [PDF]
Nature Chemical Biology, 2015 We describe a multipurpose technology platform, termed μSCALE (microcapillary single-cell analysis and laser extraction), that enables massively parallel, quantitative biochemical and biophysical measurements on millions of protein variants expressed from yeast or bacteria.
Bob Chen +8 more
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A lectin array-based methodology for the analysis of protein glycosylation
Journal of Biochemical and Biophysical Methods, 2007 Glycosylation is the most versatile and one of the most abundant protein modifications. It has a structural role as well as diverse functional roles in many specific biological functions, including cancer development, viral and bacterial infections, and autoimmunity.
Rosenfeld, R. +9 more
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Membrane Array Analysis of Tear Proteins in Ocular Cicatricial Pemphigoid [PDF]
Optometry and Vision Science, 2011 ABSTRACT Purpose. To explore non‐invasive, protein‐based, membrane array technology as a means to evaluate the global immune and angiogenic profile of tear proteins in patients with active ocular cicatricial pemphigoid (OCP). Methods.
Matilda F, Chan +8 more
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A Network-based Analysis of Polyanion-binding Proteins Utilizing Yeast Protein Arrays [PDF]
Molecular & Cellular Proteomics, 2006 The high affinity of certain cellular polyanions for many proteins (polyanion-binding proteins (PABPs)) has been demonstrated previously. It has been hypothesized that such polyanions may be involved in protein structure stabilization, stimulation of folding through chaperone-like activity, and intra- and extracellular protein transport as well as ...
Salamat-Miller, N. +6 more
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A Network-based Analysis of Polyanion-binding Proteins Utilizing Human Protein Arrays [PDF]
Journal of Biological Chemistry, 2007 The existence of interactions between many cellular proteins and various polyanionic surfaces within a cell is now well established. The functional role of such interactions, however, remains to be clearly defined. The existence of protein arrays, with a large selection of different kinds of proteins, provides a way to better address a number of ...
Salamat-Miller, N. +5 more
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Cluster analysis of protein array results via similarity of Gene Ontology annotation
BMC Bioinformatics, 2006 Background With the advent of high-throughput proteomic experiments such as arrays of purified proteins comes the need to analyse sets of proteins as an ensemble, as opposed to the traditional one-protein-at-a-time approach.
Wolting Cheryl +2 more
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PMA: Protein Microarray Analyser, a user-friendly tool for data processing and normalization
BMC Research Notes, 2018 Objective Protein microarrays provide a high-throughput platform to measure protein interactions and associated functions, and can aid in the discovery of cancer biomarkers.
Jessica Da Gama Duarte +3 more
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Biomedicines, 2020 Abnormal immune reactivity in patients with beta-thalassemia (beta-thal) major can be associated with poor prognosis. Immunome protein-array analysis represents a powerful approach to identify novel biomarkers.
Afshan Sumera +7 more
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