Results 11 to 20 of about 574,007 (259)

An Automated Approach to Assess Relative Galectin-Glycan Affinity Following Glycan Microarray Analysis

open access: yesFrontiers in Molecular Biosciences, 2022
Numerous studies have highlighted the utility of glycan microarray analysis for the elucidation of protein-glycan interactions. However, most current glycan microarray studies analyze glycan binding protein (GBP)-glycan interactions at a single protein ...
Alex D. Ho   +6 more
doaj   +1 more source

Smartphone-Based Quantitative Analysis of Protein Array Signals for Biomarker Detection in Lupus

open access: yesChemosensors, 2022
Fluorescence-based microarray offers great potential in clinical diagnostics due to its high-throughput capability, multiplex capabilities, and requirement for a minimal volume of precious clinical samples.
Guang Yang   +5 more
doaj   +1 more source

CF-PPiD technology based on cell-free protein array and proximity biotinylation enzyme for in vitro direct interactome analysis

open access: yesScientific Reports, 2022
Protein–protein interaction (PPI) analysis is a key process to understand protein functions. Recently, we constructed a human protein array (20 K human protein beads array) consisting of 19,712 recombinant human proteins produced by a wheat cell-free ...
Shusei Sugiyama   +6 more
doaj   +1 more source

RPPanalyzer: Analysis of reverse-phase protein array data [PDF]

open access: yesBioinformatics, 2010
Abstract Summary: RPPanalyzer is a statistical tool developed to read reverse-phase protein array data, to perform the basic data analysis and to visualize the resulting biological information. The R-package provides different functions to compare protein expression levels of different samples and to normalize the data.
Mannsperger, Heiko A.   +4 more
openaire   +3 more sources

In situ structural analysis of Golgi intracisternal protein arrays [PDF]

open access: yesProceedings of the National Academy of Sciences, 2015
Significance To our knowledge, this is the first detailed study of Golgi ultrastructure within unperturbed cells. Three intracisternal structures were identified, with implications for Golgi architecture and trafficking: ( i ) Bundles of filaments show how cargoes may ...
Engel, Benjamin D.   +5 more
openaire   +4 more sources

Antibody Protein Array Analysis of the Tear Film Cytokines [PDF]

open access: yesOptometry and Vision Science, 2008
ABSTRACT Purpose. Many bioactive proteins including cytokines are reported to increase in dry eye disease although the specific profile and concentration of inflammatory mediators varies considerably from study to study.
Shimin, Li   +7 more
openaire   +2 more sources

Profiling of Measles-Specific Humoral Immunity in Individuals Following Two Doses of MMR Vaccine Using Proteome Microarrays

open access: yesViruses, 2015
Introduction: Comprehensive evaluation of measles-specific humoral immunity after vaccination is important for determining new and/or additional correlates of vaccine immunogenicity and efficacy.
Iana H. Haralambieva   +6 more
doaj   +1 more source

Pro-MAP: a robust pipeline for the pre-processing of single channel protein microarray data

open access: yesBMC Bioinformatics, 2022
Background The central role of proteins in diseases has made them increasingly attractive as therapeutic targets and indicators of cellular processes. Protein microarrays are emerging as an important means of characterising protein activity.
Metoboroghene Oluwaseyi Mowoe   +6 more
doaj   +1 more source

Analyzing the Impact of Diesel Exhaust Particles on Lung Fibrosis Using Dual PCR Array and Proteomics: YWHAZ Signaling

open access: yesToxics, 2023
Air pollutants are associated with exacerbations of asthma, chronic bronchitis, and airway inflammation. Diesel exhaust particles (DEPs) can induce and worsen lung diseases.
Byeong-Gon Kim   +3 more
doaj   +1 more source

Application of mRNA Arrays for the Production of mCherry Reporter-Protein Arrays for Quantitative Gene Expression Analysis [PDF]

open access: yesACS Synthetic Biology, 2019
The development of programmable regulators that precisely and predictably control gene expression is a major goal of synthetic biology. Consequently, rapid high-throughput biochemical methods capable of quantitatively analyzing all components of gene expression would be of value in the characterization and optimization of regulator performance. In this
Masoud Norouzi   +4 more
openaire   +3 more sources

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