Analysis of protein interaction and function with a 3-dimensional MALDI-MS protein array [PDF]
Protein profiling and characterization of protein interactions in biological samples ultimately require indicator-free methods of signal detection, which likewise offer an opportunity to distinguish specific interactions from nonspecific protein binding.
Igor M. Gavin +4 more
doaj +3 more sources
RPPanalyzer Toolbox: An improved R package for analysis of reverse phase protein array data
Analysis of large-scale proteomic data sets requires specialized software tools, tailored toward the requirements of individual approaches. Here we introduce an extension of an open-source software solution for analyzing reverse phase protein array (RPPA)
Silvia von der Heyde +8 more
doaj +2 more sources
Efficiency of Disease and Disease Activity Diagnosis Models of Systemic Lupus Erythematosus Based on Protein Array Analysis. [PDF]
Zhao Y, Qi Y, Liu X, Cui Y, Zhao Z.
europepmc +3 more sources
Surface proteins play key roles in the interaction between cells and their environment, and in pathogenic microorganisms they are the best targets for drug or vaccine discovery and/or development.
Alfonso Olaya-Abril +2 more
doaj +2 more sources
Clustering and Network Analysis of Reverse Phase Protein Array Data
Molecular profiling of proteins and phosphoproteins using a reverse phase protein array (RPPA) platform, with a panel of target-specific antibodies, enables the parallel, quantitative proteomic analysis of many biological samples in a microarray format ...
Byron, Adam; id_orcid, Adam Byron
core +5 more sources
Protein western array analysis in human pituitary tumours: insights and limitations.
The molecular analysis of pituitary tumours has received a great deal of attention, although the majority of studies have concentrated on the genome and the transcriptome. We aimed to study the proteome of human pituitary adenomas.
S. Czirjak +27 more
core +4 more sources
Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma [PDF]
BackgroundAdrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been performed.
Sun Joon Moon +3 more
doaj +1 more source
Reno: Regularized non-parametric analysis of protein lysate array data [PDF]
Motivation: The reverse-phase protein lysate arrays have been used to quantify the relative expression levels of a protein in a number of cellular samples simultaneously.
He, Xuming +3 more
core +3 more sources
Context Acute lung injury (ALI) is a complex, severe inflammation disease with high mortality, and there is no specific and effective treatment for ALI.
Jing-Yi Hou +7 more
doaj +1 more source
A lectin array-based methodology for the analysis of protein glycosylation
Glycosylation is the most versatile and one of the most abundant protein modifications. It has a structural role as well as diverse functional roles in many specific biological functions, including cancer development, viral and bacterial infections, and autoimmunity.
Rakefet Rosenfeld +9 more
openalex +5 more sources

