Identification of Novel Plasma Biomarkers for Abdominal Aortic Aneurysm by Protein Array Analysis [PDF]
Abdominal aortic aneurysm (AAA) is a potentially life-threatening disease that is common in the aging population. Currently, there are no approved diagnostic biomarkers or therapeutic drugs for AAA.
Jianqiang Wu +13 more
doaj +4 more sources
Protein and Peptide Array Analysis of Autoimmune Disease [PDF]
Molecular cloning, sequencing of the human genome, and other major advances in biomedical research have contributed substantially to our understanding of autoimmune disease.
William H. Robinson +2 more
doaj +3 more sources
Urinary Protein Array Analysis to Identify Key Inflammatory Markers in Children with IgA Vasculitis Nephritis [PDF]
Chronic kidney disease is a recognised complication of immunoglobulin A vasculitis, (IgAV; formerly Henoch–Schonlein purpura—HSP). The pathophysiology of IgAV and why some patients develop significant renal involvement remains largely unknown ...
Julien Marro +4 more
doaj +2 more sources
Analysis of protein interaction and function with a 3-dimensional MALDI-MS protein array [PDF]
Protein profiling and characterization of protein interactions in biological samples ultimately require indicator-free methods of signal detection, which likewise offer an opportunity to distinguish specific interactions from nonspecific protein binding.
Igor M. Gavin +4 more
doaj +3 more sources
A Sensitive Multichannel Fluorescent Polymer Sensor Array for the Detection of Protein Fluctuations in Serum [PDF]
Serum contains diverse proteins whose concentrations vary with pathological conditions such as cancer, liver disease, neurological disorder, and infections.
Junwhee Yang +5 more
doaj +2 more sources
Discovery of crucial cytokines associated with deep vein thrombus formation by protein array analysis [PDF]
Background Expanding the number of biomarkers is imperative for studying the etiology and improving venous thromboembolism prediction. In this study, we aimed to identify promising biomarkers or targeted therapies to improve the detection accuracy of ...
Qitao Wang +6 more
doaj +2 more sources
Modified SuperCurve Method for Analysis of Reverse-Phase Protein Array Data [PDF]
Abstract Reverse-phase protein arrays (RPPAs) are widely used in biological and biomedical fields of study. One of the most popular analytic methods in RPPA data analysis is the SuperCurve method, which requires estimation of the background fluorescence level. This estimation is usually not accurate and has sample
Miao Sun, Xuelin Huang
exaly +3 more sources
Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma [PDF]
BackgroundAdrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been performed.
Sun Joon Moon +3 more
doaj +1 more source
Context Acute lung injury (ALI) is a complex, severe inflammation disease with high mortality, and there is no specific and effective treatment for ALI.
Jing-Yi Hou +7 more
doaj +1 more source
Sodium danshensu attenuates cerebral ischemia–reperfusion injury by targeting AKT1
The beneficial properties of Sodium Danshensu (SDSS) for controlling cerebral ischemia and reperfusion injury (CIRI) are elucidated here both in vivo and in vitro.
Qing Gao +10 more
doaj +1 more source

