Identification of Novel Plasma Biomarkers for Abdominal Aortic Aneurysm by Protein Array Analysis [PDF]
Abdominal aortic aneurysm (AAA) is a potentially life-threatening disease that is common in the aging population. Currently, there are no approved diagnostic biomarkers or therapeutic drugs for AAA.
Jianqiang Wu +13 more
doaj +4 more sources
Protein and Peptide Array Analysis of Autoimmune Disease [PDF]
Molecular cloning, sequencing of the human genome, and other major advances in biomedical research have contributed substantially to our understanding of autoimmune disease.
William H. Robinson +2 more
doaj +4 more sources
CF-PPiD technology based on cell-free protein array and proximity biotinylation enzyme for in vitro direct interactome analysis [PDF]
Protein–protein interaction (PPI) analysis is a key process to understand protein functions. Recently, we constructed a human protein array (20 K human protein beads array) consisting of 19,712 recombinant human proteins produced by a wheat cell-free ...
Shusei Sugiyama +6 more
doaj +2 more sources
Protein array processing software for automated semiquantitative analysis of serum antibody repertoires [PDF]
Effective immunotherapies activate natural antitumor immune responses in patients undergoing treatment. The ability to monitor immune activation in response to immunotherapy is critical in measuring treatment efficacy over time and across patient cohorts.
Ajeet Singh Yadav +4 more
openalex +2 more sources
Urinary Protein Array Analysis to Identify Key Inflammatory Markers in Children with IgA Vasculitis Nephritis [PDF]
Chronic kidney disease is a recognised complication of immunoglobulin A vasculitis, (IgAV; formerly Henoch–Schonlein purpura—HSP). The pathophysiology of IgAV and why some patients develop significant renal involvement remains largely unknown ...
Julien Marro +4 more
doaj +2 more sources
A Sensitive Multichannel Fluorescent Polymer Sensor Array for the Detection of Protein Fluctuations in Serum [PDF]
Serum contains diverse proteins whose concentrations vary with pathological conditions such as cancer, liver disease, neurological disorder, and infections.
Junwhee Yang +5 more
doaj +2 more sources
Rare osteosarcoma cell subpopulation protein array and profiling using imaging mass cytometry and bioinformatics analysis [PDF]
Background Single rare cell characterization represents a new scientific front in personalized therapy. Imaging mass cytometry (IMC) may be able to address all these questions by combining the power of MS-CyTOF and microscopy.
Izhar S. Batth +7 more
doaj +2 more sources
Discovery of crucial cytokines associated with deep vein thrombus formation by protein array analysis [PDF]
Background Expanding the number of biomarkers is imperative for studying the etiology and improving venous thromboembolism prediction. In this study, we aimed to identify promising biomarkers or targeted therapies to improve the detection accuracy of ...
Qitao Wang +6 more
doaj +2 more sources
Novel computational analysis of protein binding array data identifies direct targets of
Background The creation of a complete genome-wide map of transcription factor binding sites is essential for understanding gene regulatory networks in vivo.
Kaestner Klaus H +4 more
doaj +2 more sources
A Label-Free Fluorescent Array Sensor Utilizing Liposome Encapsulating Calcein for Discriminating Target Proteins by Principal Component Analysis [PDF]
A new fluorescent arrayed biosensor has been developed to discriminate species and concentrations of target proteins by using plural different phospholipid liposome species encapsulating fluorescent molecules, utilizing differences in permeation of the ...
Ryota Imamura +5 more
doaj +2 more sources

