Results 1 to 10 of about 570,240 (117)

Identification of Novel Plasma Biomarkers for Abdominal Aortic Aneurysm by Protein Array Analysis [PDF]

Biomolecules, 2022
Abdominal aortic aneurysm (AAA) is a potentially life-threatening disease that is common in the aging population. Currently, there are no approved diagnostic biomarkers or therapeutic drugs for AAA.
Jianqiang Wu, Wei Wang, Ting Xie, Zhaoran Chen, Lei Zhou, Xiaohong Song, Haoxuan Kan, Yanze Lv, Lianglin Wu, Fangda Li, Dan Yang, Yuexin Chen, Bao Liu, Yuehong Zheng   +13 more
doaj   +2 more sources

Urinary Protein Array Analysis to Identify Key Inflammatory Markers in Children with IgA Vasculitis Nephritis [PDF]

Children, 2022
Chronic kidney disease is a recognised complication of immunoglobulin A vasculitis, (IgAV; formerly Henoch–Schonlein purpura—HSP). The pathophysiology of IgAV and why some patients develop significant renal involvement remains largely unknown ...
Julien Marro, Andrew J. Chetwynd, Rachael D. Wright, Silothabo Dliso, Louise Oni   +4 more
doaj   +2 more sources

Discovery of crucial cytokines associated with deep vein thrombus formation by protein array analysis [PDF]

BMC Cardiovascular Disorders
Background Expanding the number of biomarkers is imperative for studying the etiology and improving venous thromboembolism prediction. In this study, we aimed to identify promising biomarkers or targeted therapies to improve the detection accuracy of ...
Qitao Wang, Junyu Chi, Wenjie Zeng, Fang Xu, Xin Li, Zhen Wang, Ming Qu   +6 more
doaj   +2 more sources

Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma [PDF]

Endocrinology and Metabolism, 2020
BackgroundAdrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been performed.
Sun Joon Moon, Jung Hee Kim, Sung Hye Kong, Chan Soo Shin   +3 more
doaj   +1 more source

Systematic identification of the interventional mechanism of Qingfei Xiaoyan Wan (QFXYW) in treatment of the cytokine storm in acute lung injury using transcriptomics-based system pharmacological analyses

Pharmaceutical Biology, 2022
Context Acute lung injury (ALI) is a complex, severe inflammation disease with high mortality, and there is no specific and effective treatment for ALI.
Jing-Yi Hou, Jia-Rong Wu, Yi-Bing Chen, Dong Xu, Shu Liu, Dan-dan Shang, Guan-Wei Fan, Yuan-Lu Cui   +7 more
doaj   +1 more source

Sodium danshensu attenuates cerebral ischemia–reperfusion injury by targeting AKT1

Frontiers in Pharmacology, 2022
The beneficial properties of Sodium Danshensu (SDSS) for controlling cerebral ischemia and reperfusion injury (CIRI) are elucidated here both in vivo and in vitro.
Qing Gao, Hao Deng, Zhengfei Yang, Qiuyue Yang, Yilin Zhang, Xiaopeng Yuan, Miao Zeng, Maojuan Guo, Wenyun Zeng, Xijuan Jiang, Bin Yu   +10 more
doaj   +1 more source

An Automated Approach to Assess Relative Galectin-Glycan Affinity Following Glycan Microarray Analysis

Frontiers in Molecular Biosciences, 2022
Numerous studies have highlighted the utility of glycan microarray analysis for the elucidation of protein-glycan interactions. However, most current glycan microarray studies analyze glycan binding protein (GBP)-glycan interactions at a single protein ...
Alex D. Ho, Shang-Chuen Wu, Nourine A. Kamili, Anna V. Blenda, Richard D. Cummings, Sean R. Stowell, Connie M. Arthur   +6 more
doaj   +1 more source

Smartphone-Based Quantitative Analysis of Protein Array Signals for Biomarker Detection in Lupus

Chemosensors, 2022
Fluorescence-based microarray offers great potential in clinical diagnostics due to its high-throughput capability, multiplex capabilities, and requirement for a minimal volume of precious clinical samples.
Guang Yang, Yaxi Li, Chenling Tang, Feng Lin, Tianfu Wu, Jiming Bao   +5 more
doaj   +1 more source

CF-PPiD technology based on cell-free protein array and proximity biotinylation enzyme for in vitro direct interactome analysis

Scientific Reports, 2022
Protein–protein interaction (PPI) analysis is a key process to understand protein functions. Recently, we constructed a human protein array (20 K human protein beads array) consisting of 19,712 recombinant human proteins produced by a wheat cell-free ...
Shusei Sugiyama, Kohdai Yamada, Miwako Denda, Satoshi Yamanaka, Satoshi Ozawa, Ryo Morishita, Tatsuya Sawasaki   +6 more
doaj   +1 more source

Profiling of Measles-Specific Humoral Immunity in Individuals Following Two Doses of MMR Vaccine Using Proteome Microarrays

Viruses, 2015
Introduction: Comprehensive evaluation of measles-specific humoral immunity after vaccination is important for determining new and/or additional correlates of vaccine immunogenicity and efficacy.
Iana H. Haralambieva, Whitney L. Simon, Richard B. Kennedy, Inna G. Ovsyannikova, Nathaniel D. Warner, Diane E. Grill, Gregory A. Poland   +6 more
doaj   +1 more source