Results 31 to 40 of about 10,846,120 (403)
From Nonspecific DNA–Protein Encounter Complexes to the Prediction of DNA–Protein Interactions [PDF]
©2009 Gao, Skolnick. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Sarai +49 more
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The connective tissues are crucial for multicellular organisms, playing many diverse roles both structurally and mechanically as well as providing a protective function. They make up the frame of the mammalian body and add strength and elasticity, while their protective function is important both on the outside of the body and inside, where they ...
Dick Heinegård +2 more
openaire +3 more sources
Protein-RNA interactions: a structural analysis [PDF]
A detailed computational analysis of 32 protein-RNA complexes is presented. A number of physical and chemical properties of the intermolecular interfaces are calculated and compared with those observed in protein-double-stranded DNA and protein-single ...
Berman, HM +4 more
core +2 more sources
The type 3 secretion system (T3SS) is essential for bacterial virulence through delivering effector proteins directly into the host cytosol. Here, we identified an alternative delivery mechanism of virulence factors mediated by the T3SS, which consists ...
Farid Tejeda-Dominguez +3 more
doaj +1 more source
Identifying well-folded de novo proteins in the new era of accurate structure prediction
Computational de novo protein design tailors proteins for target structures and oligomerisation states with high stability, which allows overcoming many limitations of natural proteins when redesigned for new functions.
Daniel Peñas-Utrilla, Enrique Marcos
doaj +1 more source
A common theme in interaction of bacterial immunoglobulin-binding proteins with immunoglobulins illustrated in the equine system [PDF]
The M protein of Streptococcus equi subsp. equi known as fibrinogen-binding protein (FgBP) is a cell wall-associated protein with antiphagocytic activity that binds IgG. Recombinant versions of the seven equine IgG subclasses were used to investigate the
Abi-Rached +49 more
core +4 more sources
Protein Binding Domains are structural motifs responsible for the peptide/protein binding activity of proteins.
semanticscholar +1 more source
A Preclinical Study Comparing the Activity and Potency of OnabotulinumtoxinA and PrabotulinumtoxinA
David C Rupp, David Canty, Catherine Rhéaume, Birgitte Sondergaard, Celina Niño, Ron S Broide, Amy D Brideau-Andersen Allergan Aesthetics, an AbbVie Company, Irvine, CA, USACorrespondence: David C Rupp, Allergan Aesthetics, an AbbVie Company, 2525 Dupont
Rupp DC +6 more
doaj
Preclinical Pharmacology of BA-TPQ, a Novel Synthetic Iminoquinone Anticancer Agent
Marine natural products and their synthetic derivatives represent a major source of novel candidate anti-cancer compounds. We have recently tested the anti-cancer activity of more than forty novel compounds based on an iminoquinone makaluvamine scaffold,
Ruiwen Zhang +11 more
doaj +1 more source
The structure of an LIM-only protein 4 (LMO4) and deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4 [PDF]
LIM-domain only protein 4 (LMO4) is a widely expressed protein with important roles in embryonic development and breast cancer. It has been reported to bind many partners, including the transcription factor Deformed epidermal autoregulatory factor-1 ...
Cubeddu, Liza +5 more
core +1 more source

