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A postreductionist framework for protein biochemistry

Nature Chemical Biology, 2011
As biochemistry ventures out from its reductionist roots, concentration effects and high surface-to-volume ratios will challenge our current understanding of biological systems, with colloidal and surface chemistry leading to new insights and approaches. How must our thinking change, what new tools will we need and how will these new tools be developed?
Tom, Laue, Borries, Demeler
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Biochemistry of fish antifreeze proteins

The FASEB Journal, 1990
Four distinct macromolecular antifreezes have been isolated and characterized from different marine fish. These include the glycoprotein antifreezes ( M r 2.5‐33 K), which are made up of a repeating tripeptide (Ala‐Ala‐Thr) n with a ...
P L, Davies, C L, Hew
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BIOCHEMISTRY OF THE PROTEIN HORMONES

Annual Review of Biochemistry, 1960
The twenty protein hormones that have been studied to date consti tute a very small family when compared to the 7 00 or 800 enzymes, which have been described. The q uestion arises as to whether this discrepancy is attribut­ able to the fact that n ature seldom makes use of protein hormones or that they are difficul t to uncover.
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Biochemistry of the Wilson's Disease Protein

2002
Copper is an essential metal, utilized as a cofactor by numerous enzymes regulating vital cellular functions, including oxidative phosphorylation, neurotransmitter biosynthesis, radical detoxification, iron uptake, and many others (for review, see refs. 1 and 2).
Svetlana Lutsenko   +4 more
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Biochemistry and Protein Interactions of the CYREN Microprotein

Biochemistry, 2023
Over the past decade, advances in genomics have identified thousands of additional protein-coding small open reading frames (smORFs) missed by traditional gene finding approaches. These smORFs encode peptides and small proteins, commonly termed micropeptides or microproteins. Several of these newly discovered microproteins have biological functions and
Lina Xie   +14 more
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Biochemistry of Nectar Proteins

Journal of Plant Biology, 2009
Floral nectar is a rich concoction of sugars, amino acids, vitamins, lipids, and other ingredients that is usually secreted at the base of a flower. Nectar is offered freely to attract large numbers of visiting pollinators to the flower. These visiting pollinators then transfer pollen between flowers, completing the plant’s sexual cycle to produce ...
Sanggyu Park, Robert W. Thornburg
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Functional Analysis by Protein Biochemistry

2013
To date a number of cereal genomes are fully sequenced and more are near completion. The information within these genomes will be of most use to scientists when every gene has been functionally characterized leading to the complete annotation of these genomes.
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Biochemistry of Peroxynitrite and Protein Tyrosine Nitration

Chemical Reviews, 2018
Peroxynitrite is a short-lived and reactive biological oxidant formed from the diffusion-controlled reaction of the free radicals superoxide (O2•-) and nitric oxide (•NO). In this review, we first analyze the biochemical evidence for the formation of peroxynitrite in vivo and the reactions that lead to it. Then, we describe the principal reactions that
Gerardo Ferrer-Sueta   +7 more
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Protein carboxyl methylation and the biochemistry of memory

bchm, 2009
Abstract Bacterial chemotaxis is mediated by two reversible protein modification chemistries: phosphorylation and carboxyl methylation. Attractants bind to membrane chemoreceptors that control the activity of a protein kinase which acts in turn to control flagellar motor activity.
Zhu, Li, Jeffry B, Stock
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Combinatorial Protein Biochemistry for Therapeutics and Proteomics

Current Pharmaceutical Biotechnology, 2004
This paper reviews progress towards the customised generation of proteins for applications as therapeutics, diagnostics and in proteomics. It particularly focuses on combinatorial approaches where proteins with pre-defined biochemical and biophysical characteristics are selected from large variant libraries.
David, Lowe, Lutz, Jermutus
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