Results 161 to 170 of about 6,112,043 (352)

Accelerated Bone Healing via Electrical Stimulation

open access: yesAdvanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun   +4 more
wiley   +1 more source

Red blood cell proteomics reveal remnant protein biosynthesis and folding pathways in PIEZO1-related hereditary xerocytosis. [PDF]

open access: yesFront Physiol, 2022
Caulier A   +11 more
europepmc   +1 more source

A unified model for the origins of spongiform degeneration and other neuropathological features in prion diseases [PDF]

open access: yesarXiv
Decades after their initial observation in prion-infected brain tissues, the identities of virus-like dense particles, varicose tubules, and oval bodies containing parallel bands and fibrils have remained elusive. Our recent work revealed that a phenotype of dilation of the endoplasmic reticulum (ER), most notable for the perinuclear space (PNS ...
arxiv  

Metabolic‐Immune Suppression Mediated by the SIRT1‐CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma

open access: yesAdvanced Science, EarlyView.
This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi   +18 more
wiley   +1 more source

STAGES OF PROTEIN BIOSYNTHESIS

open access: yes, 2023
The cells are continuously undergoing metabolic processes — the processes of synthesis and decomposition of substances. Each cell synthesizes the substances it needs. This process is called biosynthesis. Biosynthesis is the process of creating complex organic substances during biochemical reactions that occur with the help of enzymes.
openaire   +2 more sources

NECAB family of neuronal calcium-binding proteins in health and disease

open access: yesNeural Regeneration Research
The N-terminal EF-hand calcium-binding proteins 1–3 (NECAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one EF-hand calcium-binding domain and a functionally less well characterized C-terminal ...
Diones Bueno   +4 more
doaj   +1 more source

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

open access: yesAdvanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu   +12 more
wiley   +1 more source

SERTAD1 Sensitizes Breast Cancer Cells to Doxorubicin and Promotes Lysosomal Protein Biosynthesis. [PDF]

open access: yesBiomedicines, 2022
Nguyen HA   +10 more
europepmc   +1 more source

NaBC1 Boron Transporter Enables Myoblast Response to Substrate Rigidity via Fibronectin‐Binding Integrins

open access: yesAdvanced Science, EarlyView.
Cells transduce the rigidity of the environment into biochemical cues through mechanotransductive cascades that modulate cell behavior. Here, a novel role for the boron transporter NaBC1 is identified as a mechanotransducer involved in regulating cell behavior via specific crosstalk with fibronectin‐binding integrins.
Juan Gonzalez‐Valdivieso   +9 more
wiley   +1 more source

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