Results 161 to 170 of about 820,747 (349)

Tailoring Advanced Metal‐Based Nanomedicines for Adaptable Nanodynamic Disease Therapies and Theranostics

Advanced Materials, EarlyView.
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding, Wenhao Li, Ling Mei, Suling Luo, Jing Tao, Chongxiu Shi, Hongping Yang, Wei Feng, Yungchang Chen, Yu Chen, Jong Seung Kim, Xue Shen   +11 more
wiley   +1 more source

Glycodiversification of gentamicins through in vivo glycosyltransferase swapping enabled the creation of novel hybrid aminoglycoside antibiotics with potent activity and low ototoxicity

Acta Pharmaceutica Sinica B
Aminoglycosides (AGs) are a class of antibiotics with a broad spectrum of activity. However, their use is limited by safety concerns associated with nephrotoxicity and ototoxicity, as well as drug resistance.
Xinyun Jian, Cheng Wang, Shijuan Wu, Guo Sun, Chuan Huang, Chengbing Qiu, Yuanzheng Liu, Peter F. Leadlay, Dong Liu, Zixin Deng, Fuling Zhou, Yuhui Sun   +11 more
doaj   +1 more source

Rescue of Glycosylphosphatidylinositol-Anchored Protein Biosynthesis Using Synthetic Glycosylphosphatidylinositol Oligosaccharides. [PDF]

ACS Chem Biol, 2021
Guerrero PA, Murakami Y, Malik A, Seeberger PH, Kinoshita T, Varón Silva D.   +5 more
europepmc   +1 more source

New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris

Advanced Materials Interfaces, EarlyView.
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini, Mariarosaria De Simone, Martina Blasio, Claudia Zenna, Angela Tino, Eleni Stavrinidou, Silvia Santillo, Claudia Tortiglione   +7 more
wiley   +1 more source

Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis. [PDF]

, 2017
Epoxides are highly useful synthons and biosynthons for the construction of complex natural products during total synthesis and biosynthesis, respectively.
Garcia-Borràs, Marc, Hirayama, Yuichiro, Houk, KN, Li, Dehai H, Li, Li, Tang, Mancheng C, Tang, Yi, Watanabe, Kenji, Zou, Yi   +8 more
core  

Down-regulation of the bacterial protein biosynthesis machinery in response to weeks, years, and decades of soil warming. [PDF]

Sci Adv, 2022
Söllinger A, Séneca J, Borg Dahl M, Motleleng LL, Prommer J, Verbruggen E, Sigurdsson BD, Janssens I, Peñuelas J, Urich T, Richter A, Tveit AT.   +11 more
europepmc   +1 more source

Biosynthesis of Serum Proteins and Ferritin by Free and Attached Ribosomes of Rat Liver

, 1969
C M Redman
openalex   +1 more source

Citrate‐Enhanced PCL Scaffolds for Bone Tissue Engineering

Advanced Materials Interfaces, EarlyView.
This study investigates citrate‐enhanced polycaprolactone (PCL) scaffolds designed for bone tissue engineering. Utilizing 3D printing technology, four scaffold patterns (triple hexagon, grid, gyroid, zigzag) are evaluated for mechanical properties, cellular proliferation, osteogenic differentiation, and gene expression.
Muge Musmula, Oguz Sogut, Basak Aru, Gizem Gurel, Serdar Sezer, Gulderen Yanıkkaya Demirel, Umran Aydemir Sezer   +6 more
wiley   +1 more source

Inhibitors of Protein Biosynthesis

, 1967
Arthur P. Grollman
openalex   +1 more source

Disruption of Sulfur Metabolism and Redox Homeostasis in Staphylococcus aureus Using Mechanically Robust Antibiofilm Ti‐Bi Alloys

Advanced Materials Interfaces, EarlyView.
Titanium (Ti) and bismuth (Bi) are selected as alloying elements for the preparation of the Ti‐Bi binary alloy system. Biofilm formation is found to be inhibited by bismuth through the disruption of sulfur metabolism and redox homeostasis, as well as through the direct downregulation of biofilm‐associated proteins.
Lei Shi, Chen Chen, Fupeng Li, Kexin Liu, Kewei Rong, Tong Xing, Tingxian Guo, Kai Huang, Shengbing Yang, Wentao Lin, Jie Zhao   +10 more
wiley   +1 more source