Results 51 to 60 of about 4,061,795 (267)

‘Insulator bodies’ are aggregates of proteins but not of insulators [PDF]

The EMBO Reports, 2008
Chromatin insulators are thought to restrict the action of enhancers and silencers. The best-known insulators in Drosophila require proteins such as Suppressor of Hairy wing (Su(Hw)) and Modifier of mdg4 (Mod(mdg4)) to be functional. The insulator-related proteins apparently colocalize as nuclear speckles in immunostained cells.
Anton, Golovnin, Larisa, Melnikova, Ilya, Volkov, Margarita, Kostuchenko, Alexander V, Galkin, Pavel, Georgiev   +5 more
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

PML bodies in reactive sensory ganglion neurons of the Guillain–Barré syndrome

Neurobiology of Disease, 2004
Acute inflammatory demyelinating polyneuropathy (AIDP) is a type of Guillain–Barré syndrome (GBS) characterized by primary nerve demyelination sometimes with secondary axonal degeneration.
Nuria T Villagrá, José Berciano, Marcos Altable, Joaquı́n Navascués, Iñigo Casafont, Miguel Lafarga, Marı́a T Berciano   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Identification of new isolates of Bacillus thuringiensis using rep-PCR products and delta-endotoxin electron microscopy

Genetics and Molecular Biology, 2002
PCR has been used to analyze the distribution of REP (Repetitive Extragenic Palindromic) and ERIC (Enterobacterial Repetitive Intergenic Consensus) sequences (rep-PCR) found within the genome of the bacterium Bacillus thuringiensis, with the purpose to ...
A.S.G. Lima, A.M. Guidelli, I.L. Abreu, M.V.F. Lemos   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

A script to highlight hydrophobicity and charge on protein surfaces [PDF]

, 2015
The composition of protein surfaces determines both affinity and specificity of protein-protein interactions. Matching of hydrophobic contacts and charged groups on both sites of the interface are crucial to ensure specificity.
Tania eMorán Luengo, Stefan G. D. Rüdiger, Dominique Hagemans, Cellular Protein Chemistry, Ianthe A. E. M. van Belzen, Ianthe A.E.M. van Belzen, van Belzen, Ianthe A E M, Sub Cellular Protein Chemistry, Morán Luengo, Tania, Rüdiger, Stefan G D, Tania Morán Luengo, Dominique eHagemans, Hagemans, Dominique   +12 more
core   +2 more sources

Pathway to lamellar bodies for surfactant protein A [PDF]

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2010
Alveolar surfactant protein A (SP-A) is endocytosed by type II epithelial cells through clathrin-dependent uptake and targeted to lamellar bodies for resecretion. However, the mechanism for secretion of newly synthesized SP-A, whether regulated exocytosis of lamellar bodies or constitutive secretion, is unresolved. If it is the latter, lamellar body SP-
Aron B, Fisher, Chandra, Dodia, Peter, Ruckert, Jian-Qin, Tao, Sandra R, Bates   +4 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Protein composition of oil bodies from mature Brassica napus seeds

, 2009
International audienceSeed oil bodies (OBs) are intracellular particles storing lipids as food or biofuel reserves in oleaginous plants. Since Brassica napus OBs could be easily contaminated with protein bodies and/or myrosin cells, they must be purified
Thierry Chardot, Céline Boulard, Boulard, Céline, Annick Bellamy, Sabine d'Andréa, Jolivet, Pascale, Larré, Colette, Marion Barre, Rogniaux, Hélène, Chardot, Thierry, Colette Larré, Barre, Marion, Pascale Jolivet, Nathalie Nesi, d'Andrea, Sabine, Nesi, Nathalie, Hélène Rogniaux, Boulard, Celine, C., Bellamy, Annick, Larre, Colette, C., Chardot, Thierry, T., Jolivet, Pascale, P., D’andrea, Sabine   +22 more
core   +1 more source