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Anesthetic Implications of Protein C Deficiency
Anesthesia & Analgesia, 1986Chez un nourrisson de 3,5 mois deficit congenital en proteine C plusieurs anesthesies endotracheales sont realisees sans complications.
R C, Wetzel +3 more
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Severe homozygous protein C deficiency
The Journal of Pediatrics, 1984An infant with recurrent purpura fulminans in the first year of life was found to have severe homozygous deficiency of protein C (less than 1% of normal levels). The episodes of purpura fulminans were controlled by infusions of fresh frozen plasma containing protein C.
R H, Sills +4 more
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Treatment of Hereditary Protein C Deficiency with Stanozolol
Thrombosis and Haemostasis, 1987SummaryFive type I protein C deficient male patients received 5 mg stanozolol b.i.d. during 4 weeks. After four weeks of treatment plasma protein C activity increased from 0.42 to 0.74 U/ml and protein C antigen from 0.49 to 0.75 U/ml. This approximately 1.6 fold increase in plasma protein C was accompanied by an increase in factor II antigen (1.5 fold)
Broekmans, A.W. +5 more
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Pregnancy and Delivery in Protein C-Deficiency
Current Drug Targets, 2005Activated protein C (APC) is a strong inhibitor of coagulation, inactivating coagulation factors Va and VIIIa upon binding to protein S (PS) in the presence of thrombin and thrombomodulin. The normal concentration of PC in the plasma is approximately 4 microg/ml.
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Journal of the American Podiatric Medical Association, 2005
We describe the management of a patient who presented to a family-practice clinic with gangrenous digits. After a thorough evaluation, she was found to have protein C deficiency, which produced a hypercoagulable state. Differential diagnosis in the evaluation of the coagulopathic patient with appropriate hematologic tests is briefly discussed.
Travis A, Motley, Clint L, Vanlandingham
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We describe the management of a patient who presented to a family-practice clinic with gangrenous digits. After a thorough evaluation, she was found to have protein C deficiency, which produced a hypercoagulable state. Differential diagnosis in the evaluation of the coagulopathic patient with appropriate hematologic tests is briefly discussed.
Travis A, Motley, Clint L, Vanlandingham
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Laboratory Diagnosis of Protein C Deficiency
Seminars in Thrombosis and Hemostasis, 1990No assays presently available test all aspects of protein C function.
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Obstetrics & Gynecology, 1995
Complications of pregnancy, including thrombosis and increased fetal loss, have been described in women with heterozygous protein C deficiency.We report an unusual case of umbilical cord thrombosis, acute renal failure, and cutaneous venous thrombosis associated with severe protein C deficiency in the heterozygous infant of a normal mother.
T M, Goodwin, G, Gazit, E M, Gordon
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Complications of pregnancy, including thrombosis and increased fetal loss, have been described in women with heterozygous protein C deficiency.We report an unusual case of umbilical cord thrombosis, acute renal failure, and cutaneous venous thrombosis associated with severe protein C deficiency in the heterozygous infant of a normal mother.
T M, Goodwin, G, Gazit, E M, Gordon
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Protein C Deficiency in Austria
Seminars in Thrombosis and Hemostasis, 1985I, Pabinger-Fasching, E, Deutsch
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2018
This chapter discusses the pathophysiology, inheritance, and epidemiology of protein C and protein S deficiencies. The chapter discusses the impact of protein C and protein S deficiencies on pregnant women and details suggested medical and anesthetic management of affected individuals.
James P. R. Brown, Joanne Douglas
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This chapter discusses the pathophysiology, inheritance, and epidemiology of protein C and protein S deficiencies. The chapter discusses the impact of protein C and protein S deficiencies on pregnant women and details suggested medical and anesthetic management of affected individuals.
James P. R. Brown, Joanne Douglas
openaire +1 more source