Results 1 to 10 of about 2,621,675 (239)

The Functional Meaning of 5'UTR in Protein-Coding Genes. [PDF]

Int J Mol Sci, 2023
As it is well known, messenger RNA has many regulatory regions along its sequence length. One of them is the 5′ untranslated region (5’UTR), which itself contains many regulatory elements such as upstream ORFs (uORFs), internal ribosome entry sites ...
Ryczek N, Łyś A, Makałowska I.
europepmc   +2 more sources

ChIPBase v3.0: the encyclopedia of transcriptional regulations of non-coding RNAs and protein-coding genes. [PDF]

Nucleic Acids Res, 2023
Non-coding RNAs (ncRNAs) are emerging as key regulators of various biological processes. Although thousands of ncRNAs have been discovered, the transcriptional mechanisms and networks of the majority of ncRNAs have not been fully investigated.
Huang J, Zheng W, Zhang P, Lin Q, Chen Z, Xuan J, Liu C, Wu D, Huang Q, Zheng L, Liu S, Zhou K, Qu L, Li B, Yang J.   +14 more
europepmc   +2 more sources

Human protein-coding genes and gene feature statistics in 2019

BMC Research Notes, 2019
Objective A well-known limit of genome browsers is that the large amount of genome and gene data is not organized in the form of a searchable database, hampering full management of numerical data and free calculations.
Allison Piovesan, Francesca Antonaros, Lorenza Vitale, Pierluigi Strippoli, Maria Chiara Pelleri, Maria Caracausi   +5 more
doaj   +2 more sources

Phylogeny of Anophelinae using mitochondrial protein coding genes [PDF]

Royal Society Open Science, 2017
Malaria is a vector-borne disease that is a great burden on the poorest and most marginalized communities of the tropical and subtropical world. Approximately 41 species of Anopheline mosquitoes can effectively spread species of Plasmodium parasites that
Peter G. Foster, Tatiane Marques Porangaba de Oliveira, Eduardo S. Bergo, Jan E. Conn, Denise Cristina Sant’Ana, Sandra Sayuri Nagaki, Silvio Nihei, Carlos Einicker Lamas, Christian González, Caio Cesar Moreira, Maria Anice Mureb Sallum   +10 more
doaj   +2 more sources

Genome-wide annotation of protein-coding genes in pig. [PDF]

BMC Biol, 2022
There is a need for functional genome-wide annotation of the protein-coding genes to get a deeper understanding of mammalian biology. Here, a new annotation strategy is introduced based on dimensionality reduction and density-based clustering of whole ...
Karlsson M, Sjöstedt E, Oksvold P, Sivertsson Å, Huang J, Álvez MB, Arif M, Li X, Lin L, Yu J, Ma T, Xu F, Han P, Jiang H, Mardinoglu A, Zhang C, von Feilitzen K, Xu X, Wang J, Yang H, Bolund L, Zhong W, Fagerberg L, Lindskog C, Pontén F, Mulder J, Luo Y, Uhlen M.   +27 more
europepmc   +2 more sources

Features of mammalian microRNA promoters emerge from polymerase II chromatin immunoprecipitation data. [PDF]

PLoS ONE, 2009
BackgroundMicroRNAs (miRNAs) are short, non-coding RNA regulators of protein coding genes. miRNAs play a very important role in diverse biological processes and various diseases.
David L Corcoran, Kusum V Pandit, Ben Gordon, Arindam Bhattacharjee, Naftali Kaminski, Panayiotis V Benos   +5 more
doaj   +13 more sources

Beyond protein-coding genes

eLife, 2019
A long non-coding RNA called lnc-NR2F1 regulates several neuronal genes, including some involved in autism and intellectual disabilities.
Anna Lozano-Ureña, Sacri R Ferrón
doaj   +2 more sources

Fact or fiction: updates on how protein-coding genes might emerge de novo from previously non-coding DNA [version 1; referees: 3 approved]

F1000Research, 2017
Over the last few years, there has been an increasing amount of evidence for the de novo emergence of protein-coding genes, i.e. out of non-coding DNA. Here, we review the current literature and summarize the state of the field.
Jonathan F Schmitz, Erich Bornberg-Bauer
doaj   +2 more sources

A subset of conserved mammalian long non-coding RNAs are fossils of ancestral protein-coding genes

Genome Biology, 2017
Background Only a small portion of human long non-coding RNAs (lncRNAs) appear to be conserved outside of mammals, but the events underlying the birth of new lncRNAs in mammals remain largely unknown.
Hadas Hezroni, Rotem Ben-Tov Perry, Zohar Meir, Gali Housman, Yoav Lubelsky, Igor Ulitsky   +5 more
doaj   +2 more sources

Housekeeping protein-coding genes interrogated with tissue and individual variations [PDF]

Scientific Reports
Housekeeping protein-coding genes are stably expressed genes in cells and tissues that are thought to be engaged in fundamental cellular biological functions.
Kuo-Feng Tung, Chao-Yu Pan, Wen-chang Lin   +2 more
doaj   +2 more sources