Results 91 to 100 of about 2,538,848 (322)
Long non-coding RNAs in cutaneous melanoma : clinical perspectives [PDF]
, 2017 Metastatic melanoma of the skin has a high mortality despite the recent introduction of targeted therapy and immunotherapy. Long non-coding RNAs (lncRNAs) are defined as transcripts of more than 200 nucleotides in length that lack protein-coding ...
Brochez, Lieve +4 more
core +1 more source
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
The complete mitochondrial genome of Rochia nilotica (Gastropoda: Tegulidae)
Mitochondrial DNA. Part B. Resources, 2019 Rochia nilotica is a common marine gastropod species in family Tegulidae. At present, less molecular information of genus Rochia was reported. In the present study, we first determined the complete mitochondrial genome of R. nilotica.
Dianhang Jiang +5 more
doaj +1 more source
Capturing protein-coding genes across highly divergent species
BioTechniques, 2013 DNA hybridization capture combined with next generation sequencing can be used to determine the sequences of hundreds of target genes across hundreds of individuals in a single experiment. However, the approach has thus far only been successfully applied
Chenhong Li +4 more
doaj +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2020 We determined the complete mitochondrial genome of Batillaria cumingi. The B. cumingi mitochondrial genome is 16,100 bp in length, comprising 13 protein-coding genes, 22 transfer RNA genes, and two ribosomal RNA genes.
Chengrui Yan +4 more
doaj +1 more source
Universal power law behaviors in genomic sequences and evolutionary models
, 2007 We study the length distribution of a particular class of DNA sequences known as 5'UTR exons. These exons belong to the messanger RNA of protein coding genes, but they are not coding (they are located upstream of the coding portion of the mRNA) and are ...
Loredana Martignetti +2 more
core +1 more source
SinEx DB: a database for single exon coding sequences in mammalian genomes [PDF]
, 2016 Indexación: Web of Science.Eukaryotic genes are typically interrupted by intragenic, noncoding sequences termed introns. However, some genes lack introns in their coding sequence (CDS) and are generally known as 'single exon genes' (SEGs).
Cardenas, Juan Pablo +6 more
core +1 more source
Most highly expressed protein-coding genes have a single dominant isoform.
Journal of Proteome Research, 2015 Although eukaryotic cells express a wide range of alternatively spliced transcripts, it is not clear whether genes tend to express a range of transcripts simultaneously across cells, or produce dominant isoforms in a manner that is either tissue-specific
Iakes Ezkurdia +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source