Results 121 to 130 of about 2,538,848 (322)
BMC Bioinformatics, 2018 Background Long non-coding RNAs (lncRNAs) represent a novel class of non-coding RNAs having a crucial role in many biological processes. The identification of long non-coding homologs among different species is essential to investigate such roles in ...
Teresa M. R. Noviello +6 more
doaj +1 more source
Genome Biology, 2014 BackgroundNrd1 and Nab3 are essential sequence-specific yeast RNA binding proteins that function as a heterodimer in the processing and degradation of diverse classes of RNAs.
Shaun Webb +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Comprehensive RNA-Seq Data Analysis Identifies Key mRNAs and lncRNAs in Atrial Fibrillation
Frontiers in Genetics, 2019 Long non-coding RNAs (lncRNAs) are an emerging class of RNA species that may play a critical regulatory role in gene expression. However, the association between lncRNAs and atrial fibrillation (AF) is still not fully understood.
Dong-Mei Wu +27 more
doaj +1 more source
EzEditor: a versatile sequence alignment editor for both rRNA- and protein-coding genes.
International Journal of Systematic and Evolutionary Microbiology, 2014 EzEditor is a Java-based molecular sequence editor allowing manipulation of both DNA and protein sequence alignments for phylogenetic analysis. It has multiple features optimized to connect initial computer-generated multiple alignment and subsequent ...
Yoon-Seong Jeon +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Complete sequences of the mitochondrial DNA of the Grateloupia filicina (Rhodophyta)
Mitochondrial DNA. Part B. Resources, 2018 In this study, we sequenced and analyzed the complete mitogenome of Grateloupia filicina (Lamouroux) C. Agardh. The complete G. filicina mitogenome was 29,274-bp long, containing 51 genes, including 24 protein-coding genes, 1 intron, 2 rRNA genes, 24 ...
Yue Li +4 more
doaj +1 more source
Conserved syntenic clusters of protein coding genes are missing in birds
Genome Biology, 2014 BackgroundBirds are one of the most highly successful and diverse groups of vertebrates, having evolved a number of distinct characteristics, including feathers and wings, a sturdy lightweight skeleton and unique respiratory and urinary/excretion systems.
P. Lovell +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Tissue-Specific Evolution of Protein Coding Genes in Human and Mouse
bioRxiv, 2014 Protein-coding genes evolve at different rates, and the influence of different parameters, from gene size to expression level, has been extensively studied.
Nadezda Kryuchkova-Mostacci +1 more
semanticscholar +1 more source