Results 11 to 20 of about 2,621,675 (239)

Retrotransposons evolution and impact on lncRNA and protein coding genes in pigs

Mobile DNA, 2019
Background Retrotransposons are the major determinants of genome sizes and they have shaped both genes and genomes in mammalian organisms, but their overall activity, diversity, and evolution dynamics, particularly their impact on protein coding and ...
Cai Chen, Wei Wang, Xiaoyan Wang, Dan Shen, Saisai Wang, Yali Wang, Bo Gao, Klaus Wimmers, Jiude Mao, Kui Li, Chengyi Song   +10 more
doaj   +2 more sources

TAF2, within the TFIID complex, regulates the expression of a subset of protein-coding genes [PDF]

Cell Death Discovery
TFIID, one of the general transcription factor (GTF), regulates transcriptional initiation of protein-coding genes through direct binding to promoter elements and subsequent recruitment of other GTFs and RNA polymerase II. Although generally required for
I-Hsin Cheng, Wen-Chieh Pi, Chung-Hao Hsu, Yiran Guo, Jun-Lin Lai, Gang G. Wang, Bon-chu Chung, Robert G. Roeder, Wei-Yi Chen   +8 more
doaj   +2 more sources

Genome Annotation of Molting-Related Protein-Coding Genes in <i>Propsilocerus akamusi</i> Reveals Transcriptomic Responses to Heavy Metal Contamination. [PDF]

Insects
Liu W, Zhou A, Shao Z, Nie J, Yan C, Gao S, Wang Y.   +6 more
europepmc   +3 more sources

RNA editing events and expression profiles of mitochondrial protein-coding genes in the endemic and endangered medicinal plant, Corydalis saxicola. [PDF]

Front Plant Sci
Li C, Liu H, Qin M, Tan YJ, Ou XL, Chen XY, Wei Y, Zhang ZJ, Lei M.   +8 more
europepmc   +3 more sources

Hominoid-specific de novo protein-coding genes originating from long non-coding RNAs. [PDF]

PLoS Genetics, 2012
Tinkering with pre-existing genes has long been known as a major way to create new genes. Recently, however, motherless protein-coding genes have been found to have emerged de novo from ancestral non-coding DNAs.
Chen Xie, Yong E Zhang, Jia-Yu Chen, Chu-Jun Liu, Wei-Zhen Zhou, Ying Li, Mao Zhang, Rongli Zhang, Liping Wei, Chuan-Yun Li   +9 more
doaj   +1 more source

Profiling ATM regulated genes in Drosophila at physiological condition and after ionizing radiation

Hereditas, 2022
Background ATM (ataxia-telangiectasia mutated) protein kinase is highly conserved in metazoan, and plays a critical role at DNA damage response, oxidative stress, metabolic stress, immunity, RNA biogenesis etc.
Jun Liu, Tianyu Jin, Lanxi Ran, Ze Zhao, Rui Zhu, Gangcai Xie, Xiaolin Bi   +6 more
doaj   +1 more source

Variation across 141,456 human exomes and genomes reveals the spectrum of loss-of-function intolerance across human protein-coding genes

bioRxiv, 2019
Genetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic consequences of gene disruption: genes critical for an organism’s function will be depleted for such variants in natural populations, while ...
K. Karczewski, L. Francioli, G. Tiao, Beryl B. Cummings, Jessica Alföldi, Qingbo S. Wang, Ryan L. Collins, Kristen M. Laricchia, A. Ganna, Daniel P Birnbaum, L. Gauthier, H. Brand, M. Solomonson, N. Watts, Daniel Rhodes, M. Singer-Berk, Eleanor G. Seaby, J. Kosmicki, R. Walters, K. Tashman, Y. Farjoun, E. Banks, T. Poterba, Arcturus Wang, C. Seed, N. Whiffin, Jessica X. Chong, K. Samocha, E. Pierce-Hoffman, Zachary Zappala, A. O’Donnell-Luria, E. Minikel, B. Weisburd, M. Lek, J. Ware, C. Vittal, Irina M. Armean, Louis Bergelson, K. Cibulskis, K. Connolly, Miguel Covarrubias, S. Donnelly, S. Ferriera, S. Gabriel, Jeff Gentry, N. Gupta, Thibault Jeandet, D. Kaplan, Christopher Llanwarne, Ruchi Munshi, Sam Novod, Nikelle Petrillo, David Roazen, Valentín Ruano-Rubio, A. Saltzman, Molly Schleicher, José Soto, Kathleen M. Tibbetts, C. Tolonen, Gordon Wade, M. Talkowski, B. Neale, M. Daly, D. MacArthur   +63 more
semanticscholar   +1 more source

Mycobacterium Tuberculosis Proteome Microarray for Global Studies of Protein Function and Immunogenicity

Cell Reports, 2014
Poor understanding of the basic biology of Mycobacterium tuberculosis (MTB), the etiological agent of tuberculosis, hampers development of much-needed drugs, vaccines, and diagnostic tests.
Jiaoyu Deng, Lijun Bi, Lin Zhou, Shu-juan Guo, Joy Fleming, He-wei Jiang, Ying Zhou, Jia Gu, Qiu Zhong, Zong-xiu Wang, Zhonghui Liu, Rui-ping Deng, Jing Gao, Tao Chen, Wenjuan Li, Jing-fang Wang, Xude Wang, Haicheng Li, Feng Ge, Guofeng Zhu, Hai-nan Zhang, Jing Gu, Fan-lin Wu, Zhiping Zhang, Dianbing Wang, Haiying Hang, Yang Li, Li Cheng, Xiang He, Sheng-ce Tao, Xian-En Zhang   +30 more
doaj   +1 more source

Identification of protein coding genes in genomes with statistical functions based on the circular code [PDF]

, 2002
A new statistical approach using functions based on the circular code classifies correctly more than 93 % of bases in protein (coding) genes and non-coding genes of human sequences. Based on this statistical study, a research software called "Analysis of
Arquès, Arquès, Arquès, Arquès, Arquès, Berstel, Blaisdell, Borodovsky, Burge, Burset, Béal, Christian J Michel, Crick, Crick, Didier G Arquès, Eigen, Fickett, Jérôme Lacan, Karlin, Krogh, Lukashin, Nirenberg, Pavy, Salzberg, Shepherd, Shmatkov, Shulman, Smith, Staden, Staden   +29 more
core   +2 more sources

Analysis of protein-coding genetic variation in 60,706 humans

Nature, 2015
Large-scale reference data sets of human genetic variation are critical for the medical and functional interpretation of DNA sequence changes. Here we describe the aggregation and analysis of high-quality exome (protein-coding region) DNA sequence data ...
James Y. Zou
semanticscholar   +1 more source