Detecting Differences in Prion Protein Conformation by Quantifying Methionine Oxidation. [PDF]
Silva CJ, Erickson-Beltran M.
europepmc +1 more source
Changes in Ultraviolet Absorption Produced by Alteration of Protein Conformation
John W. Donovan
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B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Atomic Structure of the Human Sapovirus Capsid Reveals a Unique Capsid Protein Conformation in Caliciviruses. [PDF]
Miyazaki N+7 more
europepmc +1 more source
Alteration of 5S RNA conformation by ribosomal proteins L18 and L25 [PDF]
David G. Bear+3 more
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
PYTHIA: Deep Learning Approach for Local Protein Conformation Prediction. [PDF]
Cretin G+3 more
europepmc +1 more source
Conformational alteration of protein synthesis elongation factor EF-Tu by EF-Ts and by kirromycin. [PDF]
Thomas Blumenthal+2 more
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Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Effect of Oudemansiella raphanipies Powder on Physicochemical and Textural Properties, Water Distribution and Protein Conformation of Lower-Fat Pork Meat Batter. [PDF]
Zhao Y, Wang Y, Li K, Mazurenko I.
europepmc +1 more source