Results 11 to 20 of about 6,420,371 (402)
Predicting Binding Free Energies of PDE2 Inhibitors. The Difficulties of Protein Conformation. [PDF]
Sci Rep, 2018 Pérez-Benito L +3 more
europepmc +2 more sources
Frontiers in Molecular Neuroscience, 2022 Excitatory-inhibitory (E-I) imbalance has been shown to contribute to the pathogenesis of a wide range of neurodevelopmental disorders including autism spectrum disorders, epilepsy, and schizophrenia.
Kelvin K. Hui +5 more
doaj +1 more source
Exploring the conformational diversity of proteins [PDF]
eLife, 2022 An artificial intelligence-based method can predict distinct conformational states of membrane transporters and receptors.
Avner Schlessinger, Massimiliano Bonomi
openaire +4 more sources
Monoclonal Antibodies as Probes to Study Ligand-Induced Conformations of Troponin Subunits
Frontiers in Physiology, 2022 Striated muscle contraction and relaxation is regulated by Ca2+ at the myofilament level via conformational modulations of the troponin complex. To understand the structure–function relationship of troponin in normal muscle and in myopathies, it is ...
Monica Rasmussen +2 more
doaj +1 more source
Conformations of Proteins in Equilibrium [PDF]
Physical Review Letters, 2001 6 pages, 3 eps ...
Micheletti, Cristian +2 more
openaire +4 more sources
eLife, 2021 Insights into the conformational organization and dynamics of proteins complexes at membranes is essential for our mechanistic understanding of numerous key biological processes.
Nadia Füllbrunn +11 more
doaj +1 more source
Pathogens, 2021 Amyloid structures assemble through a repeating type of bonding called “cross-β”, in which identical sequences in many protein molecules form β-sheets that interdigitate through side chain interactions.
Peter N. Lipke +3 more
doaj +1 more source
Frontiers in Toxicology, 2023 Cerium oxide (CeO2) nanoparticles are expected to have applications in the biomedical field because of their antioxidative properties. Inorganic nanoparticles interact with proteins at the nanoparticle surface and change their conformation when ...
Masakazu Umezawa +4 more
doaj +1 more source
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Science, 2020 Structure of the nCoV trimeric spike The World Health Organization has declared the outbreak of a novel coronavirus (2019-nCoV) to be a public health emergency of international concern.
D. Wrapp +7 more
semanticscholar +1 more source
Biosurface and Biotribology, 2022 Understanding material‐protein interactions is the basis for regulating material‐blood interactions, which is a common topic of interest for medical material developers.
Xiao Chen, Jiang Chen, Nan Huang
doaj +1 more source