Results 11 to 20 of about 6,498,873 (334)
Conformations of Proteins in Equilibrium [PDF]
Physical Review Letters, 2001 6 pages, 3 eps ...
Micheletti, Cristian +2 more
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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Science, 2020 Structure of the nCoV trimeric spike The World Health Organization has declared the outbreak of a novel coronavirus (2019-nCoV) to be a public health emergency of international concern.
D. Wrapp +7 more
semanticscholar +1 more source
Cooperative Gating and Spatial Organization of Membrane Proteins through Elastic Interactions [PDF]
, 2007 Biological membranes are elastic media in which the presence of a transmembrane protein leads to local bilayer deformation. The energetics of deformation allow two membrane proteins in close proximity to influence each other's equilibrium conformation ...
Andrej Sali +4 more
core +10 more sources
Exploring the conformational diversity of proteins
eLife, 2022 An artificial intelligence-based method can predict distinct conformational states of membrane transporters and receptors.
Avner Schlessinger, Massimiliano Bonomi
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Population Shuffling of Protein Conformations [PDF]
Angewandte Chemie, 2014 AbstractMotions play a vital role in the functions of many proteins. Discrete conformational transitions to excited states, happening on timescales of hundreds of microseconds, have been extensively characterized. On the other hand, the dynamics of the ground state are widely unexplored.
Claudia Schwiegk +9 more
openaire +5 more sources
Protein Adsorption and Conformational Changes [PDF]
Molecules, 2021 Protein adsorption onto surfaces of diverse materials of both natural and artificial origin is of utmost relevance in many areas of research and technology: medicine, pharmaceutical sciences, analytical sciences, biotechnology, nanotechnology, and cell biology, among others [...]
openaire +3 more sources
Mechano-transduction: from molecules to tissues. [PDF]
, 2014 External forces play complex roles in cell organization, fate, and homeostasis. Changes in these forces, or how cells respond to them, can result in abnormal embryonic development and diseases in adults.
Dunn, Alexander R +3 more
core +2 more sources
Tracing conformational changes in proteins [PDF]
2009 IEEE International Conference on Bioinformatics and Biomedicine Workshop, 2009 Many proteins undergo extensive conformational changes as part of their functionality. Tracing these changes is important for understanding the way these proteins function. Traditional biophysics-based conformational search methods require a large number of calculations and are hard to apply to large-scale conformational motions.In this work we ...
Mark Moll +6 more
openaire +5 more sources
Limited proteolysis in the investigation of beta2-microglobulin amyloidogenic and fibrillar states. [PDF]
, 2005 Amyloid fibrils of patients treated with regular haemodialysis essentially consists of β2-microglobulin (β2-m) and its truncated species ΔN6β2-m lacking six residues at the amino terminus.
AMORESANO, ANGELA +4 more
core +1 more source
Focused conformational sampling in proteins [PDF]
The Journal of Chemical Physics, 2017 A detailed understanding of the conformational dynamics of biological molecules is difficult to obtain by experimental techniques due to resolution limitations in both time and space. Computer simulations avoid these in theory but are often too short to sample rare events reliably.
Bacci, Marco +4 more
openaire +4 more sources