Results 211 to 220 of about 6,634,608 (387)

The Heat-Induced Gel-Sol Transition in Coated Tofu: A Study on Protein Conformation and Microstructural Changes. [PDF]

Gels
Xie X, Li M, Diao X, Sun S, Wen M, Zhou X, Zhao L, Li Y, Lv P, Li B, Shen X, Huang Z, Chen H, Zhang K.   +13 more
europepmc   +1 more source

Association between Predicted Effects of TP53 Missense Variants on Protein Conformation and Their Phenotypic Presentation as Li-Fraumeni Syndrome or Hereditary Breast Cancer. [PDF]

Int J Mol Sci, 2021
Liu Y, Axell O, van Leeuwen T, Konrat R, Kharaziha P, Larsson C, Wright APH, Bajalica-Lagercrantz S.   +7 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Conformational Rearrangement in C-Reactive Protein Is Required for Proinflammatory Actions on Human Endothelial Cells [PDF]

, 2004
Tarek Khreiss, Levente József, Lawrence A. Potempa, János G. Filep   +3 more
openalex   +1 more source

3D Conducting Polymer Platforms for Electrical Control of Protein Conformation and Cellular Functions.

Journal of materials chemistry. B, 2015
A. Wan, S. Inal, Tiffany V. Williams, Karin Wang, P. Leleux, L. Estevez, E. Giannelis, C. Fischbach, G. Malliaras, D. Gourdon   +9 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mitigating Quality Deterioration of Reduced-Fat Pork Sausages During Cold Storage via Resistant Starch Incorporation: Gel Properties and Protein Conformation Study. [PDF]

Gels
Liu G, Fan J, Wang L, Liang M, Xie C, Kang Z.   +5 more
europepmc   +1 more source

Simulation of protein-folding pathways: lost in (conformational) space?

, 1995
David A. Hinds, Michael Levitt
openalex   +1 more source

Interaction and conformational dynamics of membrane‐spanning protein helices [PDF]

, 2009
Dieter Langosch, Isaiah T. Arkin
openalex   +1 more source