Results 31 to 40 of about 6,420,371 (402)
Focused conformational sampling in proteins [PDF]
The Journal of Chemical Physics, 2017 A detailed understanding of the conformational dynamics of biological molecules is difficult to obtain by experimental techniques due to resolution limitations in both time and space. Computer simulations avoid these in theory but are often too short to sample rare events reliably.
Bacci, Marco +4 more
openaire +4 more sources
Effect of Extrusion Parameters on Soybean Protein Conformation [PDF]
Shipin Kexue, 2023 The study investigated the effect of different extrusion parameters: temperature, material moisture of raw material, and screw speed on the conformation of soybean protein.
ZHANG Haojia, ZHU Xiuqing, SUN Ying
doaj +1 more source
Frontiers in Molecular Biosciences, 2018 The stereoselective flavoenzyme D-amino acid oxidase (DAAO) catalyzes the oxidative deamination of neutral and polar D-amino acids producing the corresponding α-keto acids, ammonia, and hydrogen peroxide.
Silvia Sacchi +4 more
doaj +1 more source
Foods, 2023 The quality deterioration that is induced by freezing treatment limits the development of frozen dough technology for standardized and delayed baking. In this study, laccase (LAC) and ferulic acid (FA) were employed to improve the rheological properties ...
Ni He +7 more
doaj +1 more source
In silico evidence that protein unfolding is as a precursor of the protein aggregation [PDF]
ChemPhysChem 2020, 21, 377, 2019 We present a computational study on the folding and aggregation of proteins in aqueous environment, as function of its concentration. We show how the increase of the concentration of individual protein species can induce a partial unfolding of the native conformation without the occurrence of aggregates. A further increment of the protein concentration
arxiv +1 more source
Frontiers in Cell and Developmental Biology, 2020 Owing to the wide application of miniature pigs in biomedicine, the formation mechanism of its short stature must be elucidated. The insulin-like growth factor 1 receptor (IGF-1R), which receives signals through the extracellular domain (ECD) binding ...
Chunli Wang +10 more
doaj +1 more source
Shipin gongye ke-ji, 2023 In this study, the effect of Zanthoxylum bungeanum aqueous extract (ZBAE) with the addition of 0, 0.125%, 0.25%, 0.5% and 1.0% on the characteristics of mandarin fish surimi gel, including water-holding capacity, gel strength, texture, whiteness ...
Haiqiu WEI +5 more
doaj +1 more source
Limited proteolysis in the investigation of beta2-microglobulin amyloidogenic and fibrillar states. [PDF]
, 2005 Amyloid fibrils of patients treated with regular haemodialysis essentially consists of β2-microglobulin (β2-m) and its truncated species ΔN6β2-m lacking six residues at the amino terminus.
AMORESANO, ANGELA +4 more
core +1 more source
The Conformational Plasticity of Protein Kinases [PDF]
Cell, 2002 Protein kinases operate in a large number of distinct signaling pathways, where the tight regulation of their catalytic activity is crucial to the development and maintenance of eukaryotic organisms. The catalytic domains of different kinases adopt strikingly similar structures when they are active.
Morgan Huse, John Kuriyan, John Kuriyan
openaire +3 more sources
Conformational ensembles of intrinsically disordered proteins and flexible multidomain proteins [PDF]
arXiv, 2021 Intrinsically disordered proteins (IDPs) and multidomain proteins with flexible linkers show a high level of structural heterogeneity and are best described by ensembles consisting of multiple conformations with associated thermodynamic weights.
arxiv