Results 31 to 40 of about 6,585,847 (336)

Molecular modeling of an antigenic complex between a viral peptide and a class I major histocompatibility glycoprotein [PDF]

, 1992
Computer simulation of the conformations of short antigenic peptides (&lo residues) either free or bound to their receptor, the major histocompatibility complex (MHC)- encoded glycoprotein H-2 Ld, was employed to explain experimentally determined ...
Allen, Babbit, Bjorkman, Buus, Chen, Cramer, Del Val, DeLisi, Falk, Fauchère, Garrett, Jorgensen, Kidera, Kourilsky, Krug, Lambert, Lambert, Lambert, Margalit, Maryanski, Owen, Reddehase, Reddehase, Reddehase, Rötzschke, Saper, Schwartz, Serrano, Sette, Tirado-Rives, Townsend, Townsend, Townsend, Unanue, Van Bleek, Weiner, Wendoloski, Wold, Zinkernagel   +38 more
core   +1 more source

Synonymous Mutations of Porcine Igf1r Extracellular Domain Affect Differentiation and Mineralization in MC3T3-E1 Cells

Frontiers in Cell and Developmental Biology, 2020
Owing to the wide application of miniature pigs in biomedicine, the formation mechanism of its short stature must be elucidated. The insulin-like growth factor 1 receptor (IGF-1R), which receives signals through the extracellular domain (ECD) binding ...
Chunli Wang, Siyao Wang, Songcai Liu, Yunyun Cheng, Hongwei Geng, Rui Yang, Tianqi Feng, Guanhong Lu, Xiaotong Sun, Jie Song, Linlin Hao   +10 more
doaj   +1 more source

Improving the Microstructural and Rheological Properties of Frozen Unfermented Wheat Dough with Laccase and Ferulic Acid

Foods, 2023
The quality deterioration that is induced by freezing treatment limits the development of frozen dough technology for standardized and delayed baking. In this study, laccase (LAC) and ferulic acid (FA) were employed to improve the rheological properties ...
Ni He, Zhiqin Pan, Lin Li, Xia Zhang, Yi Yuan, Yipeng Yang, Shuangyan Han, Bing Li   +7 more
doaj   +1 more source

Protein conformation in pure and hydrated deep eutectic solvents.

Physical Chemistry, Chemical Physics - PCCP, 2017
Deep eutectic solvents (DES) have recently been postulated as possible environments where protein structure may be preserved in the absence of water. Here we present our results towards understanding protein conformation in choline chloride-based DES and
Adrian Sanchez-Fernandez, Adrian Sanchez-Fernandez, K. Edler, T. Arnold, D. Venero, Andrew J Jackson, Andrew J Jackson   +6 more
semanticscholar   +1 more source

Effects of Aqueous Extract of Zanthoxylum bungeanum on Gel Properties of Mandarin Fish (Siniperca chuatsi) Surimi Gel

Shipin gongye ke-ji, 2023
In this study, the effect of Zanthoxylum bungeanum aqueous extract (ZBAE) with the addition of 0, 0.125%, 0.25%, 0.5% and 1.0% on the characteristics of mandarin fish surimi gel, including water-holding capacity, gel strength, texture, whiteness ...
Haiqiu WEI, Mingliu YANG, Yingqin ZHOU, Xubo FANG, Xiaoe CHEN, Ningning XIE   +5 more
doaj   +1 more source

Pathogenic mutations in the hydrophobic core of the human prion protein can promote structural instability and misfolding [PDF]

, 2010
Transmissible spongiform encephalopathies, or prion diseases, are caused by misfolding and aggregation of the prion protein PrP. These diseases can be hereditary in humans and four of the many disease-associated missense mutants of PrP are in the ...
Daggett, Valerie, van der Kamp, Marc W
core   +1 more source

Coupling of a Microfluidic Mixer to a Fourier-transform Infrared Spectrometer for Protein-Conformation Studies

CHIMIA, 2011
The biological properties of a protein critically depend on its conformation, which can vary as a result of changes in conditions such as pH or following the addition of various substances.
Denis Prim, Simon Crelier, Jean-Manuel Segura   +2 more
doaj   +1 more source

Mobility Measurements Probe Conformational Changes in Membrane Proteins due to Tension

, 2015
The function of membrane-embedded proteins such as ion channels depends crucially on their conformation. We demonstrate how conformational changes in asymmetric membrane proteins may be inferred from measurements of their diffusion.
Morris, Richard G., Turner, Matthew S.
core   +1 more source

CLP-based protein fragment assembly

, 2010
The paper investigates a novel approach, based on Constraint Logic Programming (CLP), to predict the 3D conformation of a protein via fragments assembly. The fragments are extracted by a preprocessor-also developed for this work- from a database of known
AGOSTINO DOVIER, ALESSANDRO DAL PALÙ, Dal Palù, Dotu, ENRICO PONTELLI, FEDERICO FOGOLARI, Levinthal   +6 more
core   +1 more source

Phosphorylation of huntingtin at residue T3 is decreased in Huntington’s disease and modulates mutant huntingtin protein conformation

Proceedings of the National Academy of Sciences of the United States of America, 2017
Significance The findings in this manuscript report on the identification of a posttranslational modification in the huntingtin protein (phosphorylation on residue T3 in the N17 region of the protein), which can revert the conformational effects of the ...
Cristina Cariulo, Lucia Azzollini, Margherita Verani, Paola Martufi, R. Boggio, Anass Chiki, Sean M. Deguire, Marta Cherubini, S. Ginés, J. L. Marsh, P. Conforti, E. Cattaneo, I. Santimone, F. Squitieri, Hilal A. Lashuel, Lara Petricca, A. Caricasole   +16 more
semanticscholar   +1 more source