Results 61 to 70 of about 3,834,350 (184)
Nanoparticles in the lung and their protein corona: the few proteins that count [PDF]
Nanotoxicology, 2016 The formation of protein coronae on nanoparticles (NPs) has been investigated almost exclusively in serum, despite the prevailing route of exposure being inhalation of airborne particles. In addition, an increasing number of nanomedicines, that exploit the airways as the site of delivery, are undergoing medical trials.
Whitwell, Harry +7 more
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PLoS ONE, 2013 BackgroundNanoparticle-protein corona complex formation involves absorption of protein molecules onto nanoparticle surfaces in a physiological environment.
Faryad Darabi Sahneh +2 more
doaj +1 more source
Identifying new therapeutic targets via modulation of protein corona formation by engineered nanoparticles. [PDF]
PLoS ONE, 2012 We introduce a promising methodology to identify new therapeutic targets in cancer. Proteins bind to nanoparticles to form a protein corona. We modulate this corona by using surface-engineered nanoparticles, and identify protein composition to provide ...
Rochelle R Arvizo +9 more
doaj +1 more source
Protein corona mediated liposomal drug delivery for bacterial infection management
Asian Journal of Pharmaceutical Sciences, 2022 Liposomes have been widely investigated as a class of promising antibiotic delivery systems for the treatment of life-threatening bacterial infections.
Qianwen Shao +7 more
doaj +1 more source
Protein Corona Composition of Gold Nanocatalysts
ACS Pharmacology & Translational ScienceThe interaction between nanoparticles (NPs) and biological environments is profoundly influenced by a stable, strongly adsorbed "hard" protein corona. This corona significantly determines the NPs' pharmacokinetics and biological destiny. Our study delves into the mechanisms by which colloidal Au nanocrystals that are synthesized electrochemically ...
Ali Akbar Ashkarran +11 more
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Advanced ScienceProtein corona alters the biological identities and interactions of nanoparticles with cells, needing to be thoroughly scrutinized before in vivo applications.
Yuting Ge +7 more
doaj +1 more source
, 2021 Proteins are biopolymers of highly varied structures taking part in almost all processes occurring in living cells. When nanoparticles (NPs) interact with proteins in biological environments, they are surrounded by a layer of biomolecules, mainly ...
Turkan Kopac
core +1 more source
The Role of the Protein Corona in Fiber Structure-Activity Relationships
Fibers, 2014 When nanomaterials enter biological fluids, they are immediately covered by biomolecules, particularly proteins, forming the so-called protein corona.
Melanie Kucki +5 more
doaj +1 more source
Nanomaterials, 2020 Biomolecules, and particularly proteins, bind on nanoparticle (NP) surfaces to form the so-called protein corona. It is accepted that the corona drives the biological distribution and toxicity of NPs.
Laurent Marichal +8 more
doaj +1 more source
ResearchUnderstanding protein corona composition is essential for evaluating their potential applications in biomedicine. Relative protein abundance (RPA), accounting for the total proteins in the corona, is an important parameter for describing the protein ...
Xiuhao Fu +11 more
doaj +1 more source