Results 51 to 60 of about 54,964 (292)
Plasma proteins facilitates placental transfer of polystyrene particles
Journal of Nanobiotechnology, 2020 Background Nanoparticles, which are exposed to biological fluids are rapidly interacting with proteins and other biomolecules forming a corona. In addition to dimension, charge and material the distinct protein corona influences the interplay of ...
Michael M. Gruber +11 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
The protein corona of circulating PEGylated liposomes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2016 Following systemic administration, liposomes are covered by a 'corona' of proteins, and preserving the surface functionality is challenging. Coating the liposome surface with polyethylene glycol (PEG) is the most widely used anti-opsonization strategy, but it cannot fully preclude protein adsorption.
PALCHETTI, SARA +7 more
openaire +2 more sources
The viral protein corona directs viral pathogenesis and amyloid aggregation
Nature Communications, 2019 The protein corona around artificial nanoparticles is known to influence activity and biological fate, the formation around viruses is less well understood.
Kariem Ezzat +25 more
doaj +1 more source
Identifying new therapeutic targets via modulation of protein corona formation by engineered nanoparticles. [PDF]
PLoS ONE, 2012 We introduce a promising methodology to identify new therapeutic targets in cancer. Proteins bind to nanoparticles to form a protein corona. We modulate this corona by using surface-engineered nanoparticles, and identify protein composition to provide ...
Rochelle R Arvizo +9 more
doaj +1 more source
Protein corona mediated liposomal drug delivery for bacterial infection management
Asian Journal of Pharmaceutical Sciences, 2022 Liposomes have been widely investigated as a class of promising antibiotic delivery systems for the treatment of life-threatening bacterial infections.
Qianwen Shao +7 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler +8 more
wiley +1 more source
NanomaterialsUnderstanding both the physicochemical and biological interactions of nanoparticles is mandatory for the biomedical application of nanomaterials. By binding proteins, nanoparticles acquire new surface identities in biological fluids, the protein corona ...
Burcu Önal Acet +4 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada +7 more
wiley +1 more source
Study of Hard Protein Corona on Lipid Surface of Composite Nanoconstruction
NanomaterialsThe composition of the protein corona covering any nanoparticle (NP) when it enters a biological fluid determines the parameters of the NP’s interaction with the body.
Anna V. Epanchintseva +5 more
doaj +1 more source