Results 31 to 40 of about 54,964 (292)

Theranostic Approach for the Protein Corona of Polysaccharide Nanoparticles [PDF]

The Chemical Record, 2020
AbstractPolysaccharide nanoparticles are promising materials in the wide range of disciplines such as medicine, nutrition, food production, agriculture, material science and others. They excel not only in their non‐toxicity and biodegradability but also in their easy preparation.
Skalickova, Sylvie, Horky, Pavel, Mlejnkova, Veronika, Skladanka, Jiri, Hosnedlova, Bozena, Ruttkay?Nedecky, Branislav, Fernandez, Carlos, Kizek, Rene   +7 more
openaire   +3 more sources

Techniques for the experimental investigation of the protein corona [PDF]

Current Opinion in Biotechnology, 2017
Due to its enormous relevance the corona formation of adsorbed proteins around nanoparticles is widely investigated. A comparison of different experimental techniques is given. Direct measurements of proteins, such as typically performed with mass spectrometry, will be compared with indirect analysis, in which instead information about the protein ...
Carolina, Carrillo-Carrion, Monica, Carril, Wolfgang J, Parak   +2 more
openaire   +2 more sources

DNA-nanoparticle interactions: Formation of a DNA corona and its effects on a protein corona [PDF]

Biointerphases, 2020
There has been much recent interest in the protein “corona,” the nonspecific adsorption of proteins on the surface of nanoparticles used in biological applications. This research investigates an analogous DNA corona. We find that particles (200 nm and 1 μm) incubated with DNA form a DNA corona, with a higher concentration of DNA adsorbed on the surface
Darbi M. Griffith, Dhanya T. Jayaram, Diane M. Spencer, David S. Pisetsky, Christine K. Payne   +4 more
openaire   +2 more sources

Biomolecular Corona Stability in Association with Plasma Cholesterol Level

Nanomaterials, 2022
Biomolecular corona is spontaneously formed on the surface of nanoparticles (NPs) when they are in contact with biological fluids. It plays an important role in the colloidal stability of NPs, which is of importance for most of their medical applications
Duong N. Trinh, Meda Radlinskaite, Jack Cheeseman, Gunter Kuhnle, Helen M. I. Osborn, Paula Meleady, Daniel I. R. Spencer, Marco P. Monopoli   +7 more
doaj   +1 more source

Personalized protein coronas: a “key” factor at the nanobiointerface

Biomaterials Science, 2014
It is now well known that the primary interactions of biological entities (e.g., tissues and cells) with nanoparticles (NPs) are strongly influenced by the protein composition of the "corona" (i.e., the NP surface attached proteins). The composition of the corona strongly depends on the protein source (e.g., human plasma).
Hajipour, M.J., Laurent, Sophie, Aghaie, A., Rezaee, F., Mahmoudi, M.   +4 more
openaire   +4 more sources

Transferrin coated nanoparticles: study of the bionano interface in human plasma.

PLoS ONE, 2012
It is now well established that the surface of nanoparticles (NPs) in a biological environment is immediately modified by the adsorption of biomolecules with the formation of a protein corona and it is also accepted that the protein corona, rather than ...
Andrzej S Pitek, David O'Connell, Eugene Mahon, Marco P Monopoli, Francesca Baldelli Bombelli, Kenneth A Dawson   +5 more
doaj   +1 more source

Corona Isolation Method Matters: Capillary Electrophoresis Mass Spectrometry Based Comparison of Protein Corona Compositions Following On-Particle versus In-Solution or In-Gel Digestion

Nanomaterials, 2019
Increased understanding of the role of the nanomaterial protein corona in driving nanomaterial uptake into, and impacts on, cells and organisms, and the consequent need for characterization of the corona, has led to a flourishing of methods for isolation
Klaus Faserl, Andrew J. Chetwynd, Iseult Lynch, James A. Thorn, Herbert H. Lindner   +4 more
doaj   +1 more source

Fixation and Visualization of Full Protein Corona on Lipid Surface of Composite Nanoconstruction

Nanomaterials, 2023
Spontaneous sorption of proteins on the nanoparticles’ surface leads to the fact that nanoparticles in biological media are always enveloped by a layer of proteins—the protein corona.
Anna V. Epanchintseva, Julia E. Poletaeva, Irina A. Bakhno, Vladimir V. Belov, Alina E. Grigor’eva, Svetlana V. Baranova, Elena I. Ryabchikova, Ilya S. Dovydenko   +7 more
doaj   +1 more source

Protein corona – from molecular adsorption to physiological complexity

Beilstein Journal of Nanotechnology, 2015
In biological environments, nanoparticles are enshrouded by a layer of biomolecules, predominantly proteins, mediating its subsequent interactions with cells.
Lennart Treuel, Dominic Docter, Michael Maskos, Roland H. Stauber   +3 more
doaj   +1 more source

Endosomal sorting results in a selective separation of the protein corona from nanoparticles

Nature Communications, 2023
Protein corona formation on nanoparticles and the resultant effects on cellular interactions is well documented, where less is known about the fate of the corona in the cell.
Shen Han, Richard da Costa Marques, Johanna Simon, Anke Kaltbeitzel, Kaloian Koynov, Katharina Landfester, Volker Mailänder, Ingo Lieberwirth   +7 more
doaj   +1 more source