Results 31 to 40 of about 3,834,350 (184)

Proteomics Analysis Reveals Distinct Corona Composition on Magnetic Nanoparticles with Different Surface Coatings: Implications for Interactions with Primary Human Macrophages. [PDF]

PLoS ONE, 2015
Superparamagnetic iron oxide nanoparticles (SPIONs) have emerged as promising contrast agents for magnetic resonance imaging. The influence of different surface coatings on the biocompatibility of SPIONs has been addressed, but the potential impact of ...
Carmen Vogt, Maria Pernemalm, Pekka Kohonen, Sophie Laurent, Kjell Hultenby, Marie Vahter, Janne Lehtiö, Muhammet S Toprak, Bengt Fadeel   +8 more
doaj   +1 more source

Theranostic Approach for the Protein Corona of Polysaccharide Nanoparticles [PDF]

The Chemical Record, 2020
Abstract Polysaccharide nanoparticles are promising materials in the wide range of disciplines such as medicine, nutrition, food production, agriculture, material science and others. They excel not only in their non‐toxicity and biodegradability but also in their easy preparation.
Skalickova, Sylvie, Horky, Pavel, Mlejnkova, Veronika, Skladanka, Jiri, Hosnedlova, Bozena, Ruttkay?Nedecky, Branislav, Fernandez, Carlos, Kizek, Rene   +7 more
openaire   +3 more sources

Techniques for the experimental investigation of the protein corona [PDF]

Current Opinion in Biotechnology, 2017
Due to its enormous relevance the corona formation of adsorbed proteins around nanoparticles is widely investigated. A comparison of different experimental techniques is given. Direct measurements of proteins, such as typically performed with mass spectrometry, will be compared with indirect analysis, in which instead information about the protein ...
Carolina, Carrillo-Carrion, Monica, Carril, Wolfgang J, Parak   +2 more
openaire   +2 more sources

DNA-nanoparticle interactions: Formation of a DNA corona and its effects on a protein corona [PDF]

Biointerphases, 2020
There has been much recent interest in the protein “corona,” the nonspecific adsorption of proteins on the surface of nanoparticles used in biological applications. This research investigates an analogous DNA corona. We find that particles (200 nm and 1 μm) incubated with DNA form a DNA corona, with a higher concentration of DNA adsorbed on the surface
Darbi M. Griffith, Dhanya T. Jayaram, Diane M. Spencer, David S. Pisetsky, Christine K. Payne   +4 more
openaire   +2 more sources

Biomolecular Corona Stability in Association with Plasma Cholesterol Level

Nanomaterials, 2022
Biomolecular corona is spontaneously formed on the surface of nanoparticles (NPs) when they are in contact with biological fluids. It plays an important role in the colloidal stability of NPs, which is of importance for most of their medical applications
Duong N. Trinh, Meda Radlinskaite, Jack Cheeseman, Gunter Kuhnle, Helen M. I. Osborn, Paula Meleady, Daniel I. R. Spencer, Marco P. Monopoli   +7 more
doaj   +1 more source

Profiling Glycoproteins Enriched by Multinanoparticle Protein Corona. [PDF]

Anal Chem
Biofluids, such as plasma and cerebrospinal fluid (CSF), present significant challenges for proteome and glycoproteome analysis due to their complex protein composition and the wide dynamic range of protein abundances. Nanoparticle (NP)-based enrichment methods that rely on the formation of protein coronas to compress dynamic range have emerged as ...
Sutherland E, Veth TS, Markuson KA, Duboff AG, Riley NM.   +4 more
europepmc   +3 more sources

Personalized protein coronas: a “key” factor at the nanobiointerface

Biomaterials Science, 2014
It is now well known that the primary interactions of biological entities (e.g., tissues and cells) with nanoparticles (NPs) are strongly influenced by the protein composition of the "corona" (i.e., the NP surface attached proteins). The composition of the corona strongly depends on the protein source (e.g., human plasma).
Hajipour, M.J., Laurent, Sophie, Aghaie, A., Rezaee, F., Mahmoudi, M.   +4 more
openaire   +4 more sources

Role of structural specificity of ZnO particles in preserving functionality of proteins in their corona

Scientific Reports, 2021
Reconfiguration of protein conformation in a micro and nano particle (MNP) protein corona due to interaction is an often-overlooked aspect in drug design and nano-medicine.
Urvashi Singh, Zeeshan Saifi, Mridul Kumar, Armin Reimers, Soami Daya Krishnananda, Rainer Adelung, Martina Baum   +6 more
doaj   +1 more source

Transferrin coated nanoparticles: study of the bionano interface in human plasma.

PLoS ONE, 2012
It is now well established that the surface of nanoparticles (NPs) in a biological environment is immediately modified by the adsorption of biomolecules with the formation of a protein corona and it is also accepted that the protein corona, rather than ...
Andrzej S Pitek, David O'Connell, Eugene Mahon, Marco P Monopoli, Francesca Baldelli Bombelli, Kenneth A Dawson   +5 more
doaj   +1 more source

Fixation and Visualization of Full Protein Corona on Lipid Surface of Composite Nanoconstruction

Nanomaterials, 2023
Spontaneous sorption of proteins on the nanoparticles’ surface leads to the fact that nanoparticles in biological media are always enveloped by a layer of proteins—the protein corona.
Anna V. Epanchintseva, Julia E. Poletaeva, Irina A. Bakhno, Vladimir V. Belov, Alina E. Grigor’eva, Svetlana V. Baranova, Elena I. Ryabchikova, Ilya S. Dovydenko   +7 more
doaj   +1 more source