Results 41 to 50 of about 3,834,350 (184)
Nanomaterials, 2019 Increased understanding of the role of the nanomaterial protein corona in driving nanomaterial uptake into, and impacts on, cells and organisms, and the consequent need for characterization of the corona, has led to a flourishing of methods for isolation
Klaus Faserl +4 more
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Protein corona alters the mechanisms of interaction between silica nanoparticles and lipid vesicles [PDF]
, 2022 The use of nanoparticles (NPs) for biomedical applications implies their delivery into the organism where they encounter biological fluids. In such biological fluids, proteins and other biomolecules adhere to the surface of the NPs forming a biomolecular
Arribas Perez, M +6 more
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Eco-Corona vs Protein Corona: Effects of Humic Substances on Corona Formation and Nanoplastic Particle Toxicity in Daphnia magna [PDF]
Environmental Science & Technology, 2020 Abstract Despite many studies on the toxicity of nanoplastic particles (NPPs) to aquatic invertebrates, the effects of ecological constituents such as humic substances (HSs) are often neglected. In our study, Daphnia magna was used to evaluate the effects of three HSs, natural organic matter (NOM), fulvic acid (FA), and humic acid (HA)
Oluniyi O. Fadare +5 more
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Endosomal sorting results in a selective separation of the protein corona from nanoparticles
Nature Communications, 2023 Protein corona formation on nanoparticles and the resultant effects on cellular interactions is well documented, where less is known about the fate of the corona in the cell.
Shen Han +7 more
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A protein corona primer for physical chemists [PDF]
The Journal of Chemical Physics, 2019 Nanoparticles present in any biological environment are exposed to extracellular proteins. These proteins adsorb on the surface of the nanoparticle forming a “protein corona.” These proteins control the interaction of nanoparticles with cells. The interaction of proteins with the nanoparticle surface is governed by physical chemistry.
openaire +2 more sources
PLoS ONE, 2017 Protein corona of nanoparticles (NPs), which forms when these particles come in to contact with protein-containing fluids, is considered as an overlooked factor in nanomedicine.
Klemen Strojan +5 more
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In situ Detection of the Protein Corona in Complex Environments [PDF]
Nature Communications, 2017 Abstract Colloidal nanoparticles (NPs) are a versatile potential platform for in vivo nanomedicine. Inside blood circulation, NPs may undergo drastic changes, such as by formation of a protein corona. The in vivo corona cannot be completely emulated by the corona formed in blood. Thus, in situ detection in complex
Monica Carril +5 more
openaire +5 more sources
Understanding aggregation-based assays: nature of protein corona and number of epitopes on antigen matters† [PDF]
RSC Advances, 2015 The development of assays that exploit aggregation of gold nanoparticles (NPs) has been widely studied for detection of biomolecules in diagnostics. These assays are often based on antibody–antigen interactions to mediate aggregation of NPs. However, the
Eugenia Li Ling Yeo +5 more
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Journal of Nanobiotechnology, 2021 Background The interactions between nanoparticles (NPs) and plasma proteins form a protein corona around NPs after entering the biological environment, which provides new biological properties to NPs and mediates their interactions with cells and ...
Zhe-Ao Zhang +11 more
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, 2021 The surfaces of pristine nanoparticles become rapidly coated by proteins in biological fluids, forming the so-called protein corona. The corona modifies key physicochemical characteristics of nanoparticle surfaces that modulate its biological and ...
Oksel Karakus, Ceyda +14 more
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