Protein Corona Prevents TiO2 Phototoxicity.
PLoS ONE, 2015 Background & aimTiO2 nanoparticles have generally low toxicity in the in vitro systems although some toxicity is expected to originate in the TiO2-associated photo-generated radical production, which can however be modulated by the radical trapping ...
Maja Garvas +5 more
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Surface hydrophobicity and rigidity determines protein corona on orally delivered nanoparticles treating colitis [PDF]
Nature CommunicationsDisease-specific protein corona adsorbed on nanocarriers determines in vivo delivery efficiency. Macrophages can orchestrate inflammation resolution and mucosa repair, making them a promising therapeutic target in colitis.
Jiawei Wu +7 more
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Advancing nanomedicine with machine learning: predicting protein corona and nano-bio interactions. [PDF]
Nanomedicine (Lond)Canchola A +5 more
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Unraveling the In Vivo Protein Corona [PDF]
Cells, 2021 Understanding the behavior of nanoparticles upon contact with a physiological environment is of urgent need in order to improve their properties for a successful therapeutic application. Most commonly, the interaction of nanoparticles with plasma proteins are studied under in vitro conditions.
Johanna Simon +5 more
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Environmental dimensions of the protein corona [PDF]
Nature Nanotechnology, 2021 The adsorption of biomolecules to the surface of engineered nanomaterials, known as corona formation, defines their biological identity by altering their surface properties and transforming the physical, chemical and biological characteristics of the particles. In the first decade since the term protein corona was coined, studies have focused primarily
Korin E. Wheeler +6 more
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Protein corona proteomics characterizes low-abundance plasma protein signatures and highlights ferroptosis-associated signals in uremic hemodialysis patients. [PDF]
Clin ProteomicsZhou F +12 more
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Harnessing Protein Corona for Biomimetic Nanomedicine Design
Biomimetics, 2022 Nanoparticles (NPs) are usually treated as multifunctional agents combining several therapeutical applications, like imaging and targeting delivery.
Zhidong Chen +4 more
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Polymeric Nanoparticles with Neglectable Protein Corona [PDF]
Small, 2020 AbstractThe current understanding of nanoparticle–protein interactions indicates that they rapidly adsorb proteins upon introduction into a living organism. The formed protein corona determines thereafter identity and fate of nanoparticles in the body.
Irina Alberg +16 more
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Unfolded Protein Corona Surrounding Nanotubes Influence the Innate and Adaptive Immune System
Advanced Science, 2021 The plasma proteins around nanoparticles (NPs) form an outer protein corona, significantly influencing the subsequent immune response. However, it was uncertain whether the protein corona around NPs influences immune response.
Jun‐Young Park +6 more
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Protein Corona, with a Twist [PDF]
ACS Central Science, 2019 Gun Su Han, Dylan W. Domaille
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