Results 221 to 230 of about 4,121,048 (281)

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Protein Crystallography in Vaccine Research and Development. [PDF]

open access: yesInt J Mol Sci, 2015
Malito E, Carfi A, Bottomley MJ.
europepmc   +1 more source

Membrane Topology and Oligomerization of Peptaibols by Solid‐State NMR Spectroscopy

open access: yesJournal of Peptide Science, Volume 32, Issue 12, December 2026.
Peptaibols of 11 to 20 residues were reconstituted in lipid bilayers of varying lipid composition and investigated by solid‐state NMR spectroscopy. Their membrane alignment is revealed by 15N spectra of static‐oriented samples and their oligomerization using 19F CODEX magic angle spinning spectra. ABSTRACT Here, we review solid‐state NMR investigations
Burkhard Bechinger, Evgeniy S. Salnikov
wiley   +1 more source

Electrochemical Determination of Amyloid Beta Biomarker Ratios in Serum Using a Pyr‐NHS‐Functionalized 3D Graphene Foam Electrode

open access: yesAnalysis &Sensing, Volume 6, Issue 6, November 2026.
An electrochemical biosensing platform based on 1‐pyrenebutyric acid N‐hydroxysuccinimide ester (Pyr‐NHS) functionalized 3D graphene foam is developed for resolving amyloid beta (Aβ42 and Aβ40) biomarker ratios in human serum with femtomolar limits of detection, offering a foundational step forward in prospective point‐of‐care screening tools.
Muhsin Dogan   +3 more
wiley   +1 more source

Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches

open access: yesAnalysis &Sensing, Volume 6, Issue 6, November 2026.
The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi   +2 more
wiley   +1 more source

Upconversion Lateral Flow Test for A1 Beta‐Casein Protein in Milk and Infant Formulas

open access: yesAnalysis &Sensing, Volume 6, Issue 6, November 2026.
A1 and A2 β‐casein have similar structures but distinct health effects. We developed a rapid UCNP‐based lateral flow assay for sensitive A1 β‐casein detection. The assay provides quantitative detection from 0.001 to 10 ng/mL, with a 61 pg/mL detection limit and 10 min analysis time.
Ziwei Wu   +6 more
wiley   +1 more source

Subzero‐Temperature NMR Observation of Protein Dynamics and Ligand Binding Enabled by Encapsulation Within Coordination Cages

open access: yesChemistry – An Asian Journal, Volume 21, Issue 21, 12 November 2026.
Encapsulation within self‐assembled coordination cages enables protein NMR analysis at subzero temperatures. Spatial isolation stabilizes proteins in acetone–water mixtures, permitting high‐resolution multidimensional NMR measurements down to −30°C. Slowed dynamics resolve discrete conformational states and reveal exchangeable hydroxy protons involved ...
Risa Ebihara   +5 more
wiley   +1 more source

Pectinase‐Based Bioprocesses for Circular Bioeconomy and Sustainable Industrial Development

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 11, Page 2906-2936, November 2026.
This picture demonstrates a unified strategy for sustainable pectinase production, focusing on microbial bioproduction, innovative strategies in enzyme engineering (Protein engineering, rational enzyme design, directed evolution and heterologous expression) and various applications in industry, including food, textiles, pulp and paper, agriculture and ...
Nisha Sharma   +6 more
wiley   +1 more source

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