Results 231 to 240 of about 8,887,267 (401)

Oxidative stress promotes degradation of the Irr protein to regulate haem biosynthesis in Bradyrhizobium japonicum [PDF]

, 2006
Jianhua Yang, Heather R. Panek, Mark R. O’Brian   +2 more
openalex   +1 more source

Author response: Variation in ubiquitin system genes creates substrate-specific effects on proteasomal protein degradation

, 2022
Mahlon Collins, Gemechu Mekonnen, Frank W. Albert   +2 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Synthetic protein degradation circuits using programmable cleavage and ligation by Sortase A. [PDF]

Nat Commun
Yang HK, Muthukumar PK, Chen W.
europepmc   +1 more source

In situ degradation of dry matter, crude protein and neutral detergent fiber of corn silages and passion fruit residue silage

, 2008
Liandra Maria Abaker Bertipaglia, Claudete Regina Alcalde, Guilherme Benko de Siqueira, Gabriel Maurício Peruca de Melo, Pedro de Andrade   +4 more
openalex   +2 more sources

Rhythmic and Light-Inducible Appearance of Clock-Associated Pseudo-Response Regulator Protein PRR9 Through Programmed Degradation in the Dark in Arabidopsis thaliana [PDF]

, 2007
Shogo Ito, N. Nakamichi, Takatoshi Kiba, Takafumi Yamashino, Toshiro Mizuno   +4 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Recent Advances in the Development of Pro-PROTAC for Selective Protein Degradation. [PDF]

Pharmaceutics
Hakem F, Abdelwaly A, Alshaman R, Alattar A, Alanazi FE, Zaitone SA, Helal MA.   +6 more
europepmc   +1 more source

Overexpression of Man2C1 leads to protein underglycosylation and upregulation of endoplasmic reticulum-associated degradation pathway [PDF]

, 2010
Coralie Bernon, Yoann Carré, Elina Kuokkanen, Marie‐Christine Slomianny, Anne‐Marie Mir, Frédéric Krzewinski, René Cacan, Pirkko Heikinheimo, Willy Morelle, Jean‐Claude Michalski, François Foulquier, Sandrine Duvet   +11 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source