Results 261 to 270 of about 1,734,521 (378)

A covalent peptide-based lysosome-targeting protein degradation platform for cancer immunotherapy. [PDF]

Nat Commun
Xiao Y, He Z, Li W, Chen D, Niu X, Yang X, Zeng W, Wang M, Qian Y, Su Y, Luo F, Chen G, Liu J, Sui X, Zhou X, Gao Y.   +15 more
europepmc   +1 more source

Effects of Cimaterol on Rabbit Growth and Myofibrillar Protein Degradation and on Calcium-Dependent Proteinase and Calpastatin Activities in Skeletal Muscle [PDF]

, 1989
N.E. Forsberg, M.A. Ilian, A. Ali-Bar, P. R. Cheeke, Nancy B. Wehr   +4 more
openalex   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Identification of a non-inhibitory aptameric ligand to CRL2^ZYG11B E3 ligase for targeted protein degradation. [PDF]

Nat Commun
Yang Z, Chen M, Ge R, Zhou P, Pan W, Song J, Ma S, Chen S, Xu C, Zhou M, Mi W, Ni H, Chen H, Yao X, Dong X, Chen Y, Zhou J, Xuan C, Dong C, Yan H, Xie S.   +20 more
europepmc   +1 more source

The rate of degradation of myofibrillar proteins of skeletal muscle in broiler and layer chickens estimated by N^r-methylhistidine in excreta [PDF]

, 1985
Kunioki HAYASHI, Yuichiro Tomita, Yoshizane MAEDA, Yoshiyuki Shinagawa, Kengo Inoue, T. Hashizume   +5 more
openalex   +1 more source

Using a Supramolecular Approach to Engineer Modular Hydrogel Platforms for Culturing Protoplasts – from General Tissue Engineering to Cellular Agriculture

Advanced Biology, EarlyView.
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers, Erik J. Slootweg, Ferdinand C. O. Los, Patricia Y. W. Dankers   +3 more
wiley   +1 more source

Non-invasive in vivo monitoring of PROTAC-mediated protein degradation using an environment-sensitive reporter. [PDF]

Nat Commun
Li T, Zong Q, Dong H, Ullah I, Pan Z, Yuan Y.   +5 more
europepmc   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Targeted protein degradation: advances in drug discovery and clinical practice. [PDF]

Signal Transduct Target Ther
Zhong G, Chang X, Xie W, Zhou X.
europepmc   +1 more source

In Vitro and Mouse Evaluation of Methods for Protecting Whey Protein and Casein from Ruminal Degradation

, 1975
Diego Rodríguez, L.D. Muller, D.J. Schingoethe   +2 more
openalex   +1 more source