Results 261 to 270 of about 1,856,978 (353)

DCAF16-Based Covalent Molecular Glues for Targeted Protein Degradation of Histone Deacetylases. [PDF]

Arch Pharm (Weinheim)
Sun T, Zhai S, Lepper S, König B, Malenica M, Honin I, Hansen FK.   +6 more
europepmc   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Unlocking the potential of targeted protein degradation <i>via</i> nanoparticle-based universal strategy. [PDF]

Acta Pharm Sin B
Zhou TQ, Sun W, Wei ZZ, Weng Y, Zhao D, Zhang M, Huang Y.   +6 more
europepmc   +1 more source

Cyclophilin A Restricts Influenza A Virus Replication through Degradation of the M1 Protein

, 2012
Xiaoling Liu, Zhendong Zhao, Chong‐Feng Xu, Lei Sun, Ji‐Long Chen, Lianfeng Zhang, Wenjun Liu   +6 more
openalex   +2 more sources

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

The timing of maternal protein degradation during mammalian preimplantation development is species-specific. [PDF]

Reproduction
Kinterova V, Rosenbaum Bartkova A, Afrin S, Kanka J, Susor A, Prochazka R, Toralova T.   +6 more
europepmc   +1 more source

UVA inactivates protein tyrosine phosphatases by calpain‐mediated degradation

, 2004
Pawan Gulati, Boyka Markova, Martin Göttlicher, Frank‐D. Böhmer, Peter Herrlich   +4 more
openalex   +1 more source

Biodegradable and Recyclable Luminescent Mixed‐Matrix‐Membranes, Hydrogels, and Cryogels based on Nanoscale Metal‐Organic Frameworks and Biopolymers

Advanced Functional Materials, EarlyView.
The study presents biodegradable and recyclable mixed‐matrix membranes (MMMs), hydrogels, and cryogels using luminescent nanoscale metal‐organic frameworks (nMOFs) and biopolymers. These bio‐nMOF‐MMMs combine europium‐based nMOFs as probes for the status of the materials with the biopolymers agar and gelatine and present alternatives to conventional ...
Moritz Maxeiner, Julian Burkhart, Kateryna Borysova, Chiara Mazzariol, Klaus Müller‐Buschbaum   +4 more
wiley   +1 more source

Author Correction: Identification of a non-inhibitory aptameric ligand to CRL2^ZYG11B E3 ligase for targeted protein degradation. [PDF]

Nat Commun
Yang Z, Chen M, Ge R, Zhou P, Pan W, Song J, Ma S, Chen S, Xu C, Zhou M, Mi W, Ni H, Chen H, Yao X, Dong X, Chen Y, Zhou J, Xuan C, Dong C, Yan H, Xie S.   +20 more
europepmc   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source