Results 271 to 280 of about 1,856,978 (353)

Inducing TRIB2 Targeted Protein Degradation to Reverse Chemoresistance in Acute Myeloid Leukaemia

Rigby E, Narayanan A, Kania E, Harris JA, Williams J, Zhang B, Liu L, Richmond L, Zhou F, Ding K, Carmody RJ, Eyers PA, Keeshan K.   +12 more
europepmc   +1 more source

Cellular parameters shaping pathways of targeted protein degradation. [PDF]

Commun Biol
Cardno A, Kennedy B, Lindon C.
europepmc   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

The contribution of native protein complexes to targeted protein degradation

Glennie L, Curnutt N, Cartwright T, Dunbar K, Chatelier BL, Wood NT, Macartney TJ, Woo CM, Sapkota GP.   +8 more
europepmc   +1 more source

Proximity-induced membrane protein degradation for cancer therapies. [PDF]

RSC Med Chem
Zhang D, Wang Z, Inuzuka H, Wei W.
europepmc   +1 more source

3D Bioinspired Hair‐Based Solar Evaporator for Efficient Water Harvesting

Advanced Functional Materials, EarlyView.
A bio‐derived solar evaporator inspired by blackbody radiation is developed using human hair waste. The vertically aligned hair structure enables broadband light absorption, efficient thermal localization, and rapid water transport, achieving high evaporation rates and stable desalination performance.
Yi Liu, Xuhui Sun, Jiaxian Zheng, Xiangfeng Lin, Jianqiushi Ma, Swellam Wafa Abdellatif Ali Sharshir, Liwei Wang, Meng An, Jie Wang, Yusuke Yamauchi, Zhanhui Yuan   +10 more
wiley   +1 more source

Targeted Protein Degradation of the Latency-Associated Nuclear Antigen Evicts Kaposi Sarcoma-Associated Herpesvirus Episomes From Infected Cells In Vitro. [PDF]

J Med Virol
McMahon S, Amer M, Hall B, Shekhar R, Renne R.   +4 more
europepmc   +1 more source

DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption

Advanced Functional Materials, EarlyView.
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim, Dai‐Hwan Kim, Priyannth R. Sundharbaabu, Chae Yeon Lee, Jina Bae, Jiyu Hyun, Young‐Ju Jang, Haeni Kim, Min‐Ho Hong, Juewen Liu, Tobias Fey, Suk Ho Bhang, Jun Hyuk Heo, Jung Heon Lee   +13 more
wiley   +1 more source

In situ construction of intracellular supramolecular assemblies as an alternative strategy for protein degradation. [PDF]

Nat Commun
Hu X, Yao Q, Wu X, Chen J, Zhang R, Zhao Y, Gao Y.   +6 more
europepmc   +1 more source

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

Advanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti, Petr Michálek, Zbyněk Heger, Martin Pumera   +3 more
wiley   +1 more source