Results 271 to 280 of about 1,734,521 (378)

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Crude Protein Degradation Kinetics of Selected Tropical Forages in Buffalo Using NorFor In Situ Standards. [PDF]

Animals (Basel)
Riaz R, Bilal RM, Hassan MU, Todaro M, Gannuscio R, Inal F, Haque MNU, Tahir MN.   +7 more
europepmc   +1 more source

Ultra‐Shallow Flat Heat Waves on Low Thermal Conductivity Flexible Polyimide Substrate for Millisecond Thermal Analysis of Materials and Bioelectronic Applications

Advanced Engineering Materials, EarlyView.
An electronic system is presented consisting of a silver thin‐film electrode on a polyimide substrate working both as a heating element and a resistive temperature sensor, generating millisecond heat pulses with very fast heating and cooling rates and a flat peak temperature with a tunable duration.
Bahman K. Boroujeni, Jan Frede, Simon T. Herrmann, Natalie Heinen, Hans Kleemann, Stephanie Pfaender   +5 more
wiley   +1 more source

TransTACs: novel heterobispecific antibodies for targeted protein degradation in cancer therapy. [PDF]

Signal Transduct Target Ther
Walther W, Torke S, Stein U.
europepmc   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source

Targeted protein degradation with bifunctional molecules as a novel therapeutic modality for Alzheimer's disease & beyond. [PDF]

Neurotherapeutics
Sandhof CA, Murray HFB, Silva MC, Haggarty SJ.   +3 more
europepmc   +1 more source

Selectivity in protein degradation during sporulation of Bacillus subtilis.

, 1976
Takahiko Mitani, Hajime KADOTA
openalex   +2 more sources

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

Advanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng, Shan Xu, Yi Lei, Huizhou He, Runbin Sun, Xingle Jin, Cheneryu Huang, Yuhao Zheng, Jianqing Peng, Lei Tang, Peng Luo, Yi Chen, Shuai Zhang   +12 more
wiley   +1 more source

Protein degradation by a component of the chaperonin-linked protease ClpP. [PDF]

Genes Cells
Ishikawa F, Homma M, Tanabe G, Uchihashi T.   +3 more
europepmc   +1 more source

Magnetic Field‐Assisted Conductive Nerve Guidance Conduit Enabling Peripheral Nerve Regeneration with Wireless Electrical Stimulation

Advanced Functional Materials, EarlyView.
This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu, Li‐Fang Zhu, Ming‐Wei Chang, Chao Li, Tingyu Wang, Rong Wang, Xinghao Yan, Baolin Wang   +7 more
wiley   +1 more source