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Nature Chemical Biology
In May 2024, ‘Protein Degradation in Focus’, a special symposium aimed at bringing together scientists in the targeted protein degradation (TPD) field, was held in Dundee, UK. David Zollman and Kirsten McAulay report on the topics discussed and the exciting outlook for science in the TPD space.
David Zollman, Kirsten McAulay
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In May 2024, ‘Protein Degradation in Focus’, a special symposium aimed at bringing together scientists in the targeted protein degradation (TPD) field, was held in Dundee, UK. David Zollman and Kirsten McAulay report on the topics discussed and the exciting outlook for science in the TPD space.
David Zollman, Kirsten McAulay
openaire +3 more sources
RAT MYOCARDIAL PROTEIN DEGRADATION
Clinical and Experimental Pharmacology and Physiology, 1981SUMMARY1. Myocardial protein degradation rates were determined by following tyrosine release from rat isolated left hemi‐atria in vitro.2. After two 20 min preincubations the rate of tyrosine release from hemi‐atria was constant for 4 h.3. Skeletal muscle protein degradation was determined by following tyrosine release from rat isolated hemi‐diaphragm (
J H, Steer, B E, Hopkins
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Mechanisms of substrate processing during ER-associated protein degradation
Nature Reviews Molecular Cell Biology, 2023Thomas Sommer, John C Christianson
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Protein degradation in the lysosome
Biochemical Society Transactions, 1985H, Glaumann +4 more
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Targeted protein degradation: A promise for undruggable proteins
Cell Chemical Biology, 2021Kusal T G Samarasinghe, Craig M Crews
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Extracellular targeted protein degradation: an emerging modality for drug discovery
Nature Reviews Drug Discovery, 2023James A Wells
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Bispecific Aptamer Chimeras Enable Targeted Protein Degradation on Cell Membranes
Angewandte Chemie - International Edition, 2021Yanyan Miao, Chao Zhang, Liqun Yang
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