Results 271 to 280 of about 1,849,171 (299)

EXTRALYSOSOMAL PROTEIN DEGRADATION

Annual Review of Biochemistry, 1986
PONTREMOLI, SANDRO, MELLONI, EDON
openaire   +3 more sources

Prey for the Proteasome: Targeted Protein Degradation—A Medicinal Chemist's Perspective

Angewandte Chemie - International Edition, 2020
Lars Wortmann, Michael Brands, Philipp M Cromm   +2 more
exaly  

Discovery of Norbornene as a Novel Hydrophobic Tag Applied in Protein Degradation

Angewandte Chemie - International Edition, 2023
Shaowen Xie, Yuan Sun, Zheying Zhu
exaly  

To degrade or not to degrade : protein handling by the proteasome

2010
The proteasome, a large multi-subunit protease that degrades proteins, must be able to distinguish between substrates deemed for destruction and accessory proteins that should be spared. The shuttle factor Rad23 operates in close proximity to the proteasome in order to deliver proteins for their degradation. While its cargo is efficiently degraded, the
openaire   +1 more source

Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation

Cell Chemical Biology, 2021
Aimo Kannt, Ivan Đikić
exaly  

Kinetic Analysis of Protein Stability Reveals Age-Dependent Degradation

Cell, 2016
Sean Erik McShane, Celine Sin, Jonathan N Wells   +2 more
exaly  

The Ubiquitin System, Autophagy, and Regulated Protein Degradation

Annual Review of Biochemistry, 2017
Alexander Varshavsky
exaly  

Small‐Molecule PROTACS: New Approaches to Protein Degradation

Angewandte Chemie - International Edition, 2016
Momar Toure, Craig M Crews
exaly  

Intracellular Protein Degradation

Biochemical Society Transactions, 1978
openaire   +2 more sources

Targeted protein degradation: current and future challenges

Current Opinion in Chemical Biology, 2020
Georg E Winter
exaly