Results 291 to 300 of about 8,887,267 (401)

An Alternative Mechanism of Glutamate Dehydrogenase Inhibition by EGCG: Promotion of Protein Degradation. [PDF]

Pharmaceuticals (Basel)
Zeng Z, Lin C, Pan C, Chen Z, Ruan BH.
europepmc   +1 more source

Engineering the Hierarchical Porosity of Granular Hydrogel Scaffolds Using Porous Microgels to Improve Cell Recruitment and Tissue Integration

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski, Sina Kheirabadi, Arian Jaberi, Zaman Ataie, Catherine L. Mojazza, Marisa L. Williamson, Anton M. Hjaltason, Aneesh Risbud, Yuanhui Xiang, Amir Sheikhi   +9 more
wiley   +1 more source

Targeted protein degradation by KLHDC2 ligands identified by high-throughput screening. [PDF]

Elife
Zhou H, Zhou T, Yu W, Liu L, Ko Y, Johnson KA, Wilson IA, Schultz PG, Bollong MJ.   +8 more
europepmc   +1 more source

Natural rubber degradation : Optimum conditions, gene and protein characterization of newly isolated Rhodococcus rhodochrous RPK1

, 2017
Kamontam Umsakul, Pimonsri Mittraparp‐arthorn   +1 more
openalex   +1 more source

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

A TRIM21-based method for targeted protein degradation. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Hu W, Qiu X, Yang Y, Wu Y, Wang C, Hu R, Li C.   +6 more
europepmc   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

The contribution of native protein complexes to targeted protein degradation

Glennie L, Curnutt N, Cartwright T, Dunbar K, Chatelier BL, Wood NT, Macartney TJ, Woo CM, Sapkota GP.   +8 more
europepmc   +1 more source

Arsenic trioxide could promote SARS-CoV-2 NSP12 protein degradation. [PDF]

J Gen Virol
Yang T, Zhu CY, Yu PH, Yang C, Naranmandura H.   +4 more
europepmc   +1 more source