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POT, an optogenetics-based endogenous protein degradation system. [PDF]

open access: yesCommun Biol
Chen Y   +7 more
europepmc   +1 more source

SE(3)-equivariant ternary complex prediction towards target protein degradation. [PDF]

open access: yesNat Commun
Xue F   +7 more
europepmc   +1 more source

Data-independent acquisition (DIA) approach for comprehensive ubiquitinome profiling in targeted protein degradation

open access: yes
Sathe G   +11 more
europepmc   +1 more source
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Targeted protein degradation

Current Opinion in Chemical Biology, 2005
The ubiquitin-proteasome pathway plays a major role in cellular protein destruction and regulates fundamental cellular processes such as the cell cycle, cell signaling, and development. By altering the substrate recognition of ubiquitin-protein ligases, their robust proteolytic activity can be re-directed to recruit and accelerate the degradation of ...
openaire   +2 more sources

Catching proteins for degradation

Science, 2023
A ubiquitin-independent pathway targets nuclear proteins to the ...
Charlotte M, Schilling   +1 more
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Regulated protein degradation

Trends in Biochemical Sciences, 2005
1 Rheinberger, H-J. (2004) A history of protein biosynthesis andribosome research. In Protein Synthesis and Ribosome Structure(Nierhaus, K.H. and Wilson, D.N., eds), pp. 1–51, Wiley-VCH Verlag2 Green, A.A. et al. (1954) The structure of haemoglobin. IV. Signdetermination by the isomorphous replacement method. Proc. Roy.Soc. A225, 287–3073 Ban, N. et al.
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