Results 191 to 200 of about 5,918,106 (339)

Molecular adaptation strategies to high temperature and thermal denaturation mechanism of the D‐trehalose/D‐maltose‐binding protein from the hyperthermophilic archaeon Thermococcus litoralis [PDF]

, 2007
Dimitrios Fessas, Maria Staiano, Alberto Barbiroli, Anna Marabotti, Alberto Schiraldi, Antonio Varriale, Mosé Rossi, Sabato D’Auria   +7 more
openalex   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

Advanced Science, EarlyView.
ABSTRACT The cytosine (C) modifications 5‐methylcytosine (mC) and 5‐hydroxymethylcytosine (hmC) are central regulatory elements of mammalian genomes. Both marks occur in double‐stranded DNA in either strand‐symmetric or ‐asymmetric fashion, but it is still poorly understood how this symmetry information is selectively read out by the nuclear proteome ...
Lena Engelhard, Zeyneb Vildan Cakil, Marlon S. Zambrano‐Mila, Simone Eppmann, Tye Gonzalez, Rasmus Linser, Petra Janning, Sidney Becker, Daniel Summerer   +8 more
wiley   +1 more source

Oxoammonium salts exert antiviral effects against coronavirus via denaturation of their spike proteins [PDF]

Ryosuke Segawa, Yusuke Sasano, Yusuke Hatakawa, Yasuhiro Fujisawa, Silvia Natsuko Akutsu, Masanobu Uchimura, Ami Ikura, Kotaro Matsumoto, Kazuki Sone, Tomoyuki Oe, Yoshiharu Iwabuchi, Masashi Ito, Noriyasu Hirasawa   +12 more
openalex   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Separation of the effects of denaturation and aggregation on whey-casein protein interactions during the manufacture of a model infant formula

, 2017
A. Joyce, A. Brodkorb, A. Kelly, J. O’Mahony   +3 more
semanticscholar   +1 more source

A Time‐Programmed Bilayer Wound Dressing for Dynamic Microenvironment Modulation and Full‐Thickness Regeneration in Diabetic Wounds

Advanced Science, EarlyView.
The Polyphenol+PDGF‐BB scaffold fabrication (Panel A) and its dual wound healing effects (Panel B: anti‐inflammation and accelerated tissue remodeling). ABSTRACT Chronic diabetic wounds suffer from dysfunctional repair programs due to accumulated advanced glycation end products (AGEs) and persistent inflammation in hyperglycemic microenvironments ...
Lei Yi, Wanqian Li, Ying Duanmu, Zihan Zhang, Shixuan Chen, Shichu Xiao, Lei Du, Miaomiao Wei   +7 more
wiley   +1 more source

Effect of Protein Denaturation and Enzyme Inhibitors on Proteasomal-Mediated Production of Peptides in Human Embryonic Kidney Cells. [PDF]

Biomolecules, 2019
Dasgupta S, Fishman MA, Castro LM, Tashima AK, Ferro ES, Fricker LD.   +5 more
europepmc   +1 more source

Heat denaturation of the antibody, a multi-domain protein

Biophysical Reviews, 2017
Yoko Akazawa-Ogawa, H. Nagai, Y. Hagihara   +2 more
semanticscholar   +1 more source

Millisecond denaturation dynamics of fluorescent proteins revealed by femtoliter container on micro-thermodevice

, 2008
Hideyuki Arata, Frédéric Gillot, Takahiko Nojima, Teruo Fujii, Hiroyuki Fujita   +4 more
openalex   +2 more sources

Injectable and In Situ Hydration‐Reinforced Hybrid Bone Cements for Accelerated Bone Regeneration

Advanced Science, EarlyView.
To enable minimally invasive bone defect repair, an injectable and hydration‐reinforced bone cement (L‐PEGS/CPC) is designed through biomimetic reconstruction. The hydrophilic L‐PEGS organic phase provides abundant nucleation sites, synergizing with its porous architecture to accelerate CPC hydration, thereby endowing the composite with exceptional ...
Xing Chen, Yifan Ma, Lingfei Zhao, Lingbin Che, Dianwen Song, Zihan Wu, Changsheng Liu, Yuan Yuan   +7 more
wiley   +1 more source