Results 1 to 10 of about 63,740 (215)
Functions and mechanisms of protein disulfide isomerase family in cancer emergence [PDF]
The endoplasmic reticulum (ER) is a multi-layered organelle that is essential for the synthesis, folding, and structural maturation of almost one-third of the cellular proteome.
Nisa Syakila A. Rahman+5 more
doaj +3 more sources
BackgroundProtein disulfide isomerase A3 (PDIA3) is a member of the protein disulfide isomerase (PDI) family that participates in protein folding through its protein disulfide isomerase function.
Zewei Tu+18 more
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Protein disulfide isomerase in cardiovascular disease
Exploring enzymes’ influence on cardiovascular disease Efforts to untangle the functions of a large family of enzymes could lead researchers to new therapies for diverse cardiovascular diseases.
Bei Xiong+3 more
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Roles of Protein Disulfide Isomerase in Breast Cancer. [PDF]
Simple Summary Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and has a poor prognosis and higher recurrence rate due to ineffective therapy.
Yang S+8 more
europepmc +2 more sources
Dual roles for a tick protein disulfide isomerase during the life cycle of the Lyme disease agent [PDF]
The protein disulfide isomerase (PDI) family is a group of enzymes that have thiol-disulfide oxidoreductase, disulfide isomerase, and redox-dependent chaperone activities.
Xiaotian Tang+5 more
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Protein disulfide isomerase A3 as novel biomarker for endometrial cancer [PDF]
ObjectiveThis study aims to investigate the potential of PDIA3 as a novel prognostic biomarker and therapeutic target for Endometrial Cancer (EC) with the ultimate goal of improving survival rates in EC patients.MethodsThis study employed a combination ...
Fanrong Yu+6 more
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Protein disulfide isomerase is essential for osteoblast differentiation in mice [PDF]
Protein disulfide isomerase (PDI) is an oxidoreductase responsible for the formation, reduction and isomerization of disulfide bonds of nascent proteins in endoplasmic reticulum (ER).
Yue Lu+5 more
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Protein disulfide isomerase (PDI) catalyzes the conversion of thiol-disulfide and plays an important role in various physiological events in animals. A PDI (OaPDI) from a tropical plant was detailed studied and it was found to be involved in response of ...
Zhengrong Zhang+5 more
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Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204 [PDF]
Redox processes can modulate vascular pathophysiology. The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stress ...
Leonardo Y. Tanaka+7 more
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A conserved protein disulfide isomerase enhances plant resistance against herbivores.
Herbivore-associated molecular patterns (HAMPs) enable plants to recognize herbivores and may help plants adjust their defense responses. Here, we report on herbivore-induced changes in a protein disulfide isomerase (PDI) widely distributed across ...
Jia-Rong Cui+9 more
semanticscholar +1 more source