Results 171 to 180 of about 86,419 (320)

Isoquercetin and Zafirlukast Cooperatively Suppress Tumor Growth and Thromboinflammatory Signaling in a Xenograft Model of Ovarian Cancer

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Treatment using either the thiol isomerase inhibitor isoquercetin or zafirlukast lowers tissue factor levels, decreases VEGF, inhibits PD‐L1, and TMEM176B in a xenograft model of ovarian cancer. A combination of the two agents, at threefold lower concentrations than either drug, significantly enhanced the inhibition further, suggesting a dual action of
Justine A. Keovilay, Jason W. Hoskins, Jean‐Pierre Kinet, Thomas C. Lines, Daniel R. Kennedy   +4 more
wiley   +1 more source

RETRACTED ARTICLE: Protein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein endothelial cells by downregulating activating transcription factor 2 [PDF]

, 2022
Jing Jia, Yueping Wang, Ruijuan Huang, Fengxia Du, Xiaozhu Shen, Qiurong Yang, Juan Li   +6 more
openalex   +1 more source

Molecular Bases of Cyclic and Specific Disulfide Interchange between Human ERO1α Protein and Protein-disulfide Isomerase (PDI) [PDF]

, 2011
Shoji Masui, Stefano Vavassori, Claudio Fagioli, Roberto Sitia, Kenji Inaba   +4 more
openalex   +1 more source

Supplementary Figure S1 from Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma

, 2023
Sergei Vatolin, James G. Phillips, Babal K. Jha, Shravya Govindgari, Jennifer J. Hu, Dale Grabowski, Yvonne Parker, Daniel J. Lindner, Fei Zhong, Clark Distelhorst, Mitchell R. Smith, Claudiu Cotta, Yan Xu, Sujatha Chilakala, Rebecca R. Kuang, Samantha Tall, Frederic J. Reu   +16 more
openalex   +1 more source

Structural and functional characterization of the oxidoreductase a-DsbA1 from wolbachia pipientis

, 2009
The α-proteobacterium Wolbachia pipientis is a highly successful intracellular endosymbiont of invertebrates that manipulates its host\u27s reproductive biology to facilitate its own maternal transmission. The fastidious nature of Wolbachia and the
Frei, Patrick, Glockshuber, Rudi, Heras, Begoña, Iturbe-Ormaetxe, Iñaki, Jarrott, Russell, Kurz, Mareike, Martin, Jennifer L., O’Neill, Scott L., Shouldice, Stephen R., Wouters, Merridee A.   +9 more
core   +1 more source

Cloning, expression, purification and characterization of Leishmania tropica PDI-2 protein

Open Life Sciences, 2016
In Leishmania species, protein disulfide isomerase (PDI) is an essential enzyme that catalyzes thiol-disulfide interchange. The present work describes the isolation, cloning, sequencing and expression of the pdI-2 gene.
Ali Dina, Abbady Abdul-Qader, Kweider Mahmoud, Soukkarieh Chadi   +3 more
doaj   +1 more source

Cell-surface protein disulfide isomerase catalyzes transnitrosation and regulates intracellular transfer of nitric oxide [PDF]

, 1999
Adrian Zai, Murray A. Rudd, Anne Ward Scribner, Joseph Loscalzo   +3 more
openalex   +1 more source

Protein disulfide isomerase in Philadelphia-negative myeloproliferative neoplasms: a case–control study

The Egyptian Journal of Internal Medicine
Background Classic Philadelphia-negative myeloproliferative neoplasms (MPNs), such as polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF), are defined by the unregulated production of bone marrow components resulting from the ...
Marwa Salah Mohammed, Alaa Alnaggar, Nehad Tawfik, Mohamed Abdelkader Morad, Eman Ahmed Abdelaziz, Nagham Yasser, Lamyaa H. Soliman, Mai Galal Elshenoufy   +7 more
doaj   +1 more source

Identification of Antithrombotic Natural Products Targeting the Major Substrate Binding Pocket of Protein Disulfide Isomerase

, 2022
Chenghui Liang, Meiqin Cai, Yanyan Xu, Wei Fu, Juhong Wu, Yu‐Rong Liu, Xinyuan Liao, Jiamin Ning, Jinyu Li, Mingdong Huang, Cai Yuan   +10 more
openalex   +1 more source

Three-dimensional structure and domain-domain interactions of protein disulfide isomerase as revealed by NMR spectroscopy

, 2003
Michiko Nakano, Yoshihiro Yamaguchi, Chiho Murakami, T. Harada, Eiji Kurimoto, Osamu Asami, T. Kazino, Kenji Inaba, Koichi Kato   +8 more
openalex   +2 more sources