Protein disulfide isomerase A3 as novel biomarker for endometrial cancer [PDF]
Frontiers in Oncology, 2023 ObjectiveThis study aims to investigate the potential of PDIA3 as a novel prognostic biomarker and therapeutic target for Endometrial Cancer (EC) with the ultimate goal of improving survival rates in EC patients.MethodsThis study employed a combination ...
Fanrong Yu +6 more
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The flexibility and dynamics of protein disulfide isomerase [PDF]
Proteins: Structure, Function, and Bioinformatics, 2016 We have studied the mobility of the multidomain folding catalyst, protein disulfide isomerase (PDI), by a coarse‐graining approach based on flexibility.
Rudolf A. Römer +5 more
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Inhibition of Protein Disulfide Isomerase in Thrombosis. [PDF]
Basic & Clinical Pharmacology & Toxicology, 2016 AbstractThis MiniReview addresses our current understanding of the mechanisms by which protein disulfide isomerase (PDI) mediates thrombus formation and discusses the potential of blocking thrombosis by targeting PDI. Thiol isomerases are ubiquitous oxidoreductases primarily localized to the endoplasmic reticulum (ER) where they serve a critical role ...
Roelof H. Bekendam, R. Flaumenhaft
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Protein disulfide isomerase is essential for osteoblast differentiation in mice [PDF]
Communications BiologyProtein disulfide isomerase (PDI) is an oxidoreductase responsible for the formation, reduction and isomerization of disulfide bonds of nascent proteins in endoplasmic reticulum (ER).
Yue Lu +5 more
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Protein disulfide isomerase is essential for spermatogenesis in mice [PDF]
JCI InsightSpermatogenesis requires precise posttranslational control in the endoplasmic reticulum (ER), but the mechanism remains largely unknown. The protein disulfide isomerase (PDI) family is a group of thiol oxidoreductases responsible for catalyzing the ...
Yaqiong Zhang +7 more
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Frontiers in Plant Science, 2018 Protein disulfide isomerase (PDI) catalyzes the conversion of thiol-disulfide and plays an important role in various physiological events in animals. A PDI (OaPDI) from a tropical plant was detailed studied and it was found to be involved in response of ...
Zhengrong Zhang +5 more
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Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204 [PDF]
Frontiers in PhysiologyRedox processes can modulate vascular pathophysiology. The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stress ...
Leonardo Y. Tanaka +7 more
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Protein Disulfide Isomerase and Extracellular Adherence Protein Cooperatively Potentiate Staphylococcal Invasion into Endothelial Cells [PDF]
Microbiol Spectr, 2023 Marleen Leidecker +10 more
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Tannic acid inhibits TNF-α signaling by targeting the protein disulfide isomerase and alleviates symptoms in an imiquimod-induced psoriasis mouse model [PDF]
Cell Commun SignalWenhua Jin +16 more
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