Results 181 to 190 of about 8,703,040 (401)

Engineering subunit association of multisubunit proteins: A dimeric streptavidin [PDF]

, 1997
Takeshi Sano, Sándor Vajda, Cassandra L. Smith, Charles R. Cantor   +3 more
openalex   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Protein engineering in haemoglobin [PDF]

Nature, 1992
Giardina, B, Scatena, R, Clementi, M, Cerroni, L, CONDO', SAVERIO GIOVANNI, Nuutinen, M, Brix, O.   +6 more
openaire   +5 more sources

Recruitment of substrate-specificity properties from one enzyme into a related one by protein engineering.

, 1987
J A Wells, Brian C. Cunningham, Thomas P. Graycar, David A. Estell   +3 more
openalex   +1 more source

Unified rational protein engineering with sequence-based deep representation learning

Nature Methods, 2019
E. C. Alley, Grigory Khimulya, Surojit Biswas, Mohammed Alquraishi, G. Church   +4 more
semanticscholar   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Current status and future directions for the development of human papillomavirus vaccines

Frontiers in Immunology
The development of human papillomavirus (HPV) vaccines has made substantive progress, as represented by the approval of five prophylactic vaccines since 2006.
Rui Wang, Hongpeng Huang, Chulin Yu, Xuefeng Li, Yang Wang, Liangzhi Xie, Liangzhi Xie   +6 more
doaj   +1 more source

ProLLaMA: A Protein Language Model for Multi-Task Protein Language Processing [PDF]

arXiv
Large Language Models (LLMs) have achieved remarkable performance in multiple Natural Language Processing (NLP) tasks. Under the premise that protein sequences constitute the protein language, Protein Language Models(PLMs) have advanced the field of protein engineering.
arxiv  

Protein Engineering [PDF]

FEBS Letters, 2013
openaire   +2 more sources

Synergy in Protein Engineering [PDF]

, 1996
Anthony Woods, J. Guy Guillemette, Jonathan C. Parrish, Michael B. Smith, CarmichaelJ. A. Wallace   +4 more
openalex   +1 more source