Results 181 to 190 of about 29,093 (266)

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

Small current, big potential: bridging mechanistic insight of the SK channel with translational promise

open access: yes
The Journal of Physiology, EarlyView.
Yang Zheng   +2 more
wiley   +1 more source

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 928-941, April 2026.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park   +22 more
wiley   +1 more source

Effects of Bisphosphonates on Bone Micro‐Architecture of Children With Duchenne Muscular Dystrophy: A Prospective Comparative Study

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Duchenne muscular dystrophy (DMD) is an X‐linked recessive disorder that affects dystrophin production, characterized by progressive neuromuscular dysfunction, often accompanied by osteoporosis. We prospectively evaluate the effects of bisphosphonates on bone micro‐architecture reflected by trabecular bone score (TBS) of patients ...
Songqi Wang   +11 more
wiley   +1 more source

The beta1-adrenergic receptor in the heart. [PDF]

open access: yesCell Death Discov
Xu W   +8 more
europepmc   +1 more source

Trends and Disparities in Atrial Fibrillation‐Related Mortality Among Older Adults With Parkinson's Disease in the United States, 2000–2023

open access: yesJournal of Arrhythmia, Volume 42, Issue 2, April 2026.
Central Illustration: 24‐year US analysis reveals rising atrial fibrillation‐related mortality in older adults with Parkinson's disease, highlighting significant disparities by sex, race, and geography. ABSTRACT Background The coexistence of Parkinson's Disease (PD) and Atrial Fibrillation (AF) is increasingly recognized, but the mortality burden and ...
Mohid Zulfiqar   +6 more
wiley   +1 more source

Synthetic deformylated α-helical PSMα3 as a selective inhibitor of human amyloid aggregation. [PDF]

open access: yesSci Rep
Kalitnik A   +6 more
europepmc   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi   +5 more
wiley   +1 more source

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