Results 241 to 250 of about 29,093 (266)
Some of the next articles are maybe not open access.
Neuroscience Letters, 2008
Fisetin (3,3',4',7-tetrahydroxyflavone) has been found to be neuroprotective, induce neuronal differentiation, enhance memory, and inhibit the aggregation of the amyloid beta protein (Abeta) that may cause the progressive neuronal loss in Alzheimer's disease.
Tatsuhiro, Akaishi +6 more
openaire +2 more sources
Fisetin (3,3',4',7-tetrahydroxyflavone) has been found to be neuroprotective, induce neuronal differentiation, enhance memory, and inhibit the aggregation of the amyloid beta protein (Abeta) that may cause the progressive neuronal loss in Alzheimer's disease.
Tatsuhiro, Akaishi +6 more
openaire +2 more sources
The International Journal of Biochemistry & Cell Biology, 2011
Amyloid-like fibrils have been associated with the pathogenesis of human prion diseases. Prion peptide of aa 106-126 (PrP106-126) exhibits many PrP(Sc)-like biochemical features, forming amyloid-like fibrils in vitro. Here, we found that the recombinant yeast-derived molecular chaperon Hsp104 inhibited significantly the fibril assembly of the synthetic
Ying-Hui, Liu +10 more
openaire +2 more sources
Amyloid-like fibrils have been associated with the pathogenesis of human prion diseases. Prion peptide of aa 106-126 (PrP106-126) exhibits many PrP(Sc)-like biochemical features, forming amyloid-like fibrils in vitro. Here, we found that the recombinant yeast-derived molecular chaperon Hsp104 inhibited significantly the fibril assembly of the synthetic
Ying-Hui, Liu +10 more
openaire +2 more sources
Chemistry Letters, 2016
In this study, we firstly report inhibition of amyloid β42 (Aβ42) fibrillation, which is related to the progression of Alzheimer’s disease, by digestion using proteases, combined with Aβ42 isolation using an immunoaffinity membrane. Especially, digestion of Aβ42 with carboxypeptidase Y (CPY) is effective for the inhibition of Aβ42 fibrillation ...
Masaki Saito +3 more
openaire +1 more source
In this study, we firstly report inhibition of amyloid β42 (Aβ42) fibrillation, which is related to the progression of Alzheimer’s disease, by digestion using proteases, combined with Aβ42 isolation using an immunoaffinity membrane. Especially, digestion of Aβ42 with carboxypeptidase Y (CPY) is effective for the inhibition of Aβ42 fibrillation ...
Masaki Saito +3 more
openaire +1 more source
Mechanisms, regulation and functions of the unfolded protein response
Nature Reviews Molecular Cell Biology, 2020Claudio Hetz +2 more
exaly
Mechanism of gelsolin-mediated inhibition of fibrillization of amyloid beta-protein
Neurobiology of Aging, 2000Abha Chauhan, Ved Chauhan
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Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing
Nature Reviews Molecular Cell Biology, 2021Simon Alberti, Anthony A Hyman
exaly
The mechanisms of integral membrane protein biogenesis
Nature Reviews Molecular Cell Biology, 2021Ramanujan Shankar Hegde, Robert J Keenan
exaly
Aloe Vera Inhibits Protein Fibrillation: Mechanistic Biophysical Evaluation
LangmuirAnu Jain, Nand Kishore
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Derivatization with fatty acids in peptide and protein drug discovery
Nature Reviews Drug Discovery, 2022Peter Kurtzhals +2 more
exaly
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Nature Reviews Molecular Cell Biology, 2012Claudio Hetz
exaly