Results 211 to 220 of about 257,652 (357)

Single Molecule Visualization of Cardiac Myosin-Binding Protein C N-terminal Fragments Interacting with Thin Filaments: Mechanisms of Calcium Sensitization [PDF]

, 2018
Alessio V. Inchingolo, Samantha Beck Previs, Michael J. Previs, David M. Warshaw, Neil M. Kad   +4 more
openalex   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T

International Journal of Biological Sciences, 2006
Protein dephosphorylation by protein phosphatase 1 (PP1), acting in concert with protein kinase C (PKC) and protein kinase A (PKA), is a pivotal regulatory mechanism of protein phosphorylation.
doaj  

RAD51AP1 is a versatile RAD51 modulator. [PDF]

Proc Natl Acad Sci U S A
Kuhlen L, Argunhan B, Liang P, Zhong J, Masino L, Zhang X.   +5 more
europepmc   +1 more source

De novo design of pH-responsive self-assembling helical protein filaments [PDF]

Hao Shen, Eric M. Lynch, Susrut Akkineni, Joseph L. Watson, Justin Decarreau, Neville P. Bethel, Issa Benna, William Sheffler, Daniel P. Farrell, Frank DiMaio, Emmanuel Derivery, James J. De Yoreo, Justin M. Kollman, David Baker   +13 more
openalex   +1 more source

Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting

Advanced Healthcare Materials, EarlyView.
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig, Zan Lamberger, Lys Sprenger, Vivien Priebe, Camilla Mussoni, Denitsa Docheva, Kristina Andelovic, Jürgen Groll, Sahar Salehi, Gregor Lang, Matthias Ryma   +10 more
wiley   +1 more source

Atomic mechanisms of full-length ASC-mediated inflammasome assembly. [PDF]

Nat Commun
Xue D, Ni F, Liu S, Yan H, Luo Z, Fu G, Wang Q, Ma J.   +7 more
europepmc   +1 more source

Cytoplasmic 8 S glucocorticoid receptor binds to actin filaments through the 90-kDa heat shock protein moiety

, 1991
Yoshihiko Miyata, Ichiro Yahara
openalex   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Multiscale Simulation of Phosphofructokinase-1 Assemblies: Capturing the Interplay between Specific and Transient Interactions. [PDF]

J Phys Chem B
Hazrati MK, Miclot T, Timr S.
europepmc   +1 more source