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Comprehensive Folding Variations for Protein Folding [PDF]
Proteins: Structure, Function, and Bioinformatics, 2022 The revelation of protein folding is a challenging subject in both discovery and description. Except acquirement of accurate 3D structure for protein stable state, another big hurdle is how to discover structural flexibility for protein innate character.
Jiaan Yang +10 more
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Protein folds and protein folding [PDF]
Protein Engineering Design and Selection, 2010 The classification of protein folds is necessarily based on the structural elements that distinguish domains. Classification of protein domains consists of two problems: the partition of structures into domains and the classification of domains into sets of similar structures (or folds).
R Dustin, Schaeffer, Valerie, Daggett
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Folding of Proteins with Diverse Folds [PDF]
Biophysical Journal, 2006 Using parallel tempering simulations with high statistics, we investigate the folding and thermodynamic properties of three small proteins with distinct native folds: the all-helical 1RIJ, the all-sheet beta3s, and BBA5, which has a mixed helix-sheet fold.
Mohanty, S., Hansmann, U. H. E.
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Single-Molecule Force Spectroscopy of Protein Folding [PDF]
, 2021 The use of force probes to induce unfolding and refolding of single molecules through the application of mechanical tension, known as single-molecule force spectroscopy (SMFS), has proven to be a powerful tool for studying the dynamics of protein folding.
Petrosyan, Rafayel +2 more
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Flexible protein folding by ant colony optimization [PDF]
, 2008 Protein structure prediction is one of the most challenging topics in bioinformatics. As the protein structure is found to be closely related to its functions, predicting the folding structure of a protein to judge its functions is meaningful to the ...
Hu, X. +5 more
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The Standard Scrapie Cell Assay: Development, Utility and Prospects
Viruses, 2015 Prion diseases are a family of fatal neurodegenerative diseases that involve the misfolding of a host protein, PrPC. Measuring prion infectivity is necessary for determining efficacy of a treatment or infectivity of a prion purification procedure; animal
Jacques van der Merwe +3 more
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Progress in Nuclear Magnetic Resonance Spectroscopy, 2017 Protein folding is a highly complex process proceeding through a number of disordered and partially folded nonnative states with various degrees of structural organization. These transiently and sparsely populated species on the protein folding energy landscape play crucial roles in driving folding toward the native conformation, yet some of these ...
Zhuravleva, A, Korzhnev, DM
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Protein Folding and Macromolecular Dynamics: Fundamental Limits of Length and Time Scales [PDF]
, 2012 In this thesis, physics-based models of protein folding at the secondary and tertiary level are developed to resolve long-standing issues of protein folding kinetics.
Lin, Milo Miaoyu
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On the kinematics of protein folding [PDF]
Journal of Computational Chemistry, 2003 AbstractWe offer simple solutions to three kinematic problems that occur in the folding of proteins. We show how to construct suitably local elementary Monte Carlo moves, how to close a loop, and how to fold a loop without breaking the bond that closes it. © 2003 Wiley Periodicals, Inc.
Sean Cahill +2 more
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Protein folding disorders: Toward a basic biological paradigm [PDF]
, 2010 Mechanistic 'physics' models of protein folding fail to account for the observed spectrum of protein folding and aggregation disorders, suggesting that a more appropriately biological paradigm will be needed for understanding the etiology ...
Rodrick Wallace
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