Results 21 to 30 of about 3,681,813 (263)
Regulated increase in folding capacity prevents unfolded protein stress in the ER [PDF]
, 2010 Stimulation of thyrocytes with thyroid stimulating hormone (TSH) leads to a morphological change and a massive increase in thyroglobulin (Tg) production.
Mkrtchian, S. +11 more
core +1 more source
, 1980 Recent studies of the relationship between protein sequence and protein structure are reviewed. A detailed discussion of past attempts to predict the structure of a protein from its amino acid sequence, the protein folding problem, is presented and the ...
Cohen, Fred E.
core +1 more source
Tryptophan-Tryptophan energy migration as a tool to follow apoflavodoxin folding [PDF]
, 2008 Submolecular details of Azotobacter vinelandii apoflavodoxin (apoFD) (un)folding are revealed by time-resolved fluorescence anisotropy using wild-type protein and variants lacking one or two of apoFD's three tryptophans.
Mierlo, C.P.M., van +14 more
core +1 more source
Properties of the free energy barriers for folding of the [alpha]-amylase inhibitor tendamistat [PDF]
, 2005 The goal of this work was to improve our understanding of the properties of the free energy barriers in protein folding. We used the small all-[beta]-sheet protein tendamistat as a model protein. Tendamistat contains two disulfide bridges and folds and
Schätzle, Manuela
core +1 more source
PROTEIN FOLDING AND HETEROPOLYMERS [PDF]
, 1997 57 pages, 7 figures. Uses lprocl.sty (included). To appear in " Spin glasses and random fields ", A.P.
Garel, Thomas +2 more
openaire +2 more sources
Dynamics in unfolded polypeptide chains as model for elementary steps in protein folding [PDF]
, 2004 This thesis deals with the dynamics of unfolded polypeptide chains as model for the earliest steps in protein folding. Starting from an ensemble of unfolded conformations a folding polypeptide chain has to form specific backbone and side-chain ...
Krieger, Florian
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FDserver: A web service for protein folding research [PDF]
, 2008 *Summary:* To facilitate the study of protein folding, we have developed a web service for protein folding rate and folding type prediction as well as for the calculation of a variety of topological parameters of protein structure, which is freely ...
Ling-Ling Chen +2 more
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source