Results 111 to 120 of about 7,803,058 (302)

Characterisation of the E.coli and Pseudomonas aeruginosa TolA-TolB interaction [PDF]

, 2012
The Tol-Pal complex of Gram-negative bacteria is a highly conserved family of interacting proteins that span the periplasm, from inner to outer membrane.
Cassels, Eoin
core   +3 more sources

Computational approaches for detecting protein complexes from protein interaction networks: a survey

BMC Genomics, 2010
Background Most proteins form macromolecular complexes to perform their biological functions. However, experimentally determined protein complex data, especially of those involving more than two protein partners, are relatively limited in the current ...
Kwoh Chee-Keong, Wu Min, Li Xiaoli, Ng See-Kiong   +3 more
doaj   +1 more source

Protein molecular surface mapped at different geometrical resolutions.

PLoS ONE, 2013
Many areas of biochemistry and molecular biology, both fundamental and applications-orientated, require an accurate construction, representation and understanding of the protein molecular surface and its interaction with other, usually small, molecules ...
Dan V Nicolau, Ewa Paszek, Florin Fulga, Dan V Nicolau   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Mapping interactions of Chikungunya virus nonstructural proteins

Virus Research, 2012
The four nonstructural proteins (nsPs1-4) of Chikungunya virus (CHIKV) play important roles involving enzymatic activities and specific interactions with both viral and host components, during different stages of viral pathogenesis. Elucidation of the presence and/or absence of interactions among nsPs in a systematic manner is thus of scientific ...
R, Sreejith, Jyoti, Rana, Namrata, Dudha, Kapila, Kumar, Reema, Gabrani, Sanjeev K, Sharma, Amita, Gupta, Sudhanshu, Vrati, Vijay K, Chaudhary, Sanjay, Gupta   +9 more
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Urandangi, Queensland [cartographic material] /

, 1951
1st ed. Topographic map of Urandangi region, Queensland, showing classes of roads, railway and telephone lines, fences, state boundries, watercourses and dams, windpumps, and bore, tank and well classifictions. Relief shown by hachures and spot heights.;
Australia. National Mapping Section.
core  

Integrative RNA-seq analysis reveals immune-related hub genes NR4A1 and FOSB in recurrent spontaneous abortion: A bioinformatics study

International Journal of Reproductive BioMedicine
Background: Recurrent spontaneous abortion (RSA) impacts 1–5% of women of reproductive age, constituting a significant health issue. Despite advances in our understanding of RSA, the fundamental molecular mechanisms remain inadequately defined ...
Kosar Babaei, Saman Morovat, Hossein Mozdarani, Misa Naghdipour Mirsadeghi, Seyed Reza Mirhafez, Ebrahim Mirzajani, Mohsen Aziminezhad, Ali Akbar Samadani   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source