Results 261 to 270 of about 251,250 (306)

Mapping Protein: Carbohydrate Interactions

Current Protein & Peptide Science, 2003
Many biologically important interactions occur between proteins and carbohydrates. The examination of these interactions at the atomic level is critical not only in understanding the nature of these interactions and their biological role, but also in the design of effective modulators of these interactions.
Gerald F, Audette, Louis T J, Delbaere, Jim, Xiang   +2 more
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Deciphering complex protein interaction kinetics using Interaction Map

Biochemical and Biophysical Research Communications, 2012
Cellular receptor systems are expected to present complex ligand interaction patterns that cannot be evaluated assuming a simple one ligand:one receptor interaction model. We have previously evaluated heterogeneous interactions using an alternative method to regression analysis, called Interaction Map (IM).
Danièle, Altschuh, Hanna, Björkelund, John, Strandgård, Laurence, Choulier, Magnus, Malmqvist, Karl, Andersson   +5 more
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Protein‐Protein Interaction Mapping by 2C‐BioID

Current Protocols in Cell Biology, 2019
AbstractProtein‐protein interactions (PPIs) add an essential layer of complexity to the information encoded by the genome. Modulation of such interactions is a key feature of most, if not all, cellular activities and allows cells to respond rapidly to both internal and external signals and stimuli. In this respect, the development of the BioID assay to
Alexandre, Chojnowski, Hendrikje, Werner, Matthew, Cook, Radoslaw M, Sobota, Brian, Burke, Colin L, Stewart   +5 more
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Mapping protein–protein interactions by mass spectrometry

Current Opinion in Biotechnology, 2006
Mass spectrometry is currently at the forefront of technologies for mapping protein-protein interactions, as it is a highly sensitive technique that enables the rapid identification of proteins from a variety of biological samples. When used in combination with affinity purification and/or chemical cross-linking, whole or targeted protein interaction ...
Julian, Vasilescu, Daniel, Figeys
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Deconvolution of Targeted Protein–Protein Interaction Maps

Journal of Proteome Research, 2012
Current proteomic techniques allow researchers to analyze chosen biological pathways or an ensemble of related protein complexes at a global level via the measure of physical protein-protein interactions by affinity purification mass spectrometry (AP-MS). Such experiments yield information-rich but complex interaction maps whose unbiased interpretation
Alexey, Stukalov, Giulio, Superti-Furga, Jacques, Colinge   +2 more
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Mapping Protein–Protein Interactions by Quantitative Proteomics

2010
Proteins exert their function inside a cell generally in multiprotein complexes. These complexes are highly dynamic structures changing their composition over time and cell state. The same protein may thereby fulfill different functions depending on its binding partners.
Dengjel, Jörn, Kratchmarova, Irina, Blagoev, Blagoy   +2 more
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Protein interaction maps on the fly

Nature Biotechnology, 2004
A protein interaction map for the fruit fly Drosophila melanogaster promises to facilitate functional analysis of many eukaryotic proteins.
Uetz, P., Pankratz, M. J.
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Mapping of RNA–protein interactions

Analytica Chimica Acta, 2009
RNA-protein interactions are important biological events that perform multiple functions in all living organisms. The wide range of RNA interactions demands diverse conformations to provide contacts for the selective recognition of proteins. Various analytical procedures are presently available for quantitative analyses of RNA-protein complexes, but ...
openaire   +2 more sources