Results 271 to 280 of about 7,803,058 (302)

Construction and Prediction of Protein-Protein Interaction Maps

2002
With the completion of full genome sequence for several model organisms, new approaches are emerging to comprehensively characterize the function of gene products. In these so-called functional proteomics approaches, large-scale assays on the complete set of proteins of a given organism — the proteome — enable the study of the function of proteins in ...
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Proteolytic DNA for Mapping Protein−DNA Interactions

Biochemistry, 2002
We describe a technique to determine sites on proteins involved in protein-DNA interactions. DNA was synthesized via polymerase chain reaction (PCR) to produce four polynucleotide products with phosphorothioate nucleotides at the A, T, G, or C residues.
Brian D, Schmidt, Claude F, Meares
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Progress and potential of Drosophila protein interaction maps

Pharmacogenomics, 2000
Protein-protein interactions mediate many important cellular processes and are central to the mechanisms by which most proteins function. Charting the interactions among the proteins involved in a process has been an essential step in characterising the function of proteins and pathways.
C A, Stanyon, R L, Finley
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A Protein Interaction Map of Drosophila melanogaster

Science, 2003
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid–based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map
L, Giot, J S, Bader, C, Brouwer, A, Chaudhuri, B, Kuang, Y, Li, Y L, Hao, C E, Ooi, B, Godwin, E, Vitols, G, Vijayadamodar, P, Pochart, H, Machineni, M, Welsh, Y, Kong, B, Zerhusen, R, Malcolm, Z, Varrone, A, Collis, M, Minto, S, Burgess, L, McDaniel, E, Stimpson, F, Spriggs, J, Williams, K, Neurath, N, Ioime, M, Agee, E, Voss, K, Furtak, R, Renzulli, N, Aanensen, S, Carrolla, E, Bickelhaupt, Y, Lazovatsky, A, DaSilva, J, Zhong, C A, Stanyon, R L, Finley, K P, White, M, Braverman, T, Jarvie, S, Gold, M, Leach, J, Knight, R A, Shimkets, M P, McKenna, J, Chant, J M, Rothberg   +48 more
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Mapping protein?protein interactions by bioinformatics and cross-linking

Analytical and Bioanalytical Chemistry, 2004
Protein–protein interactions play a key role in many cellular processes. Determining the protein interaction network is one of the major tasks of functional proteomics. Databases of protein interactions integrate the large amounts of information available on protein– protein interactions, ranging from functional interactions (such as which proteins are
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Mapping Protein−Protein Interactions in Solution by NMR Spectroscopy

Biochemistry, 2001
NMR is very well suited to the study of especially weak protein-protein interactions, as no crystallization is required. The available NMR methods to this end are reviewed and illustrated with applications from the recent biochemical literature: intermolecular NOEs, cross-saturation, chemical shift perturbation, dynamics and exchange perturbation ...
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Selection of Multi-Drug Targets against Drug-Resistant Mycobacterium tuberculosis XDR1219 Using the Hyperbolic Mapping of the Protein Interaction Network

International Journal of Molecular Sciences, 2023
Miguel Andrade, Aimilia-Christina Vagiona, Reaz Uddin   +2 more
exaly  

Protein-protein interaction mapping of phospholipase

2023
Ananya Samanta, Semanti Ghosh, Angshuman Bagchi   +2 more
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Straightforward Protein-Protein Interaction Interface Mapping via Random Mutagenesis and Mammalian Protein Protein Interaction Trap (MAPPIT)

International Journal of Molecular Sciences, 2019
Frank Peelman, Delphine Masschaele, Jan Tavernier   +2 more
exaly  

Prediction of ProteinProtein Interaction Pocket Using L‐Shaped PLS Approach and Its Visualizations by Generative Topographic Mapping

Molecular Informatics, 2014
Kimito Funatsu
exaly