Results 251 to 260 of about 435,247 (293)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

An <i>In silico</i> analysis on the phosphorylation dependent structural and thermal stability of thermophilic proteins. [PDF]

Front Chem
Arunachalam S, Gnanasekaran R.
europepmc   +1 more source

SpheronizaTor: Spherical Voxelization for Interpretable Protein Microenvironment Modeling. [PDF]

Comput Struct Biotechnol J
Silva JCF, Richardson M, Cediel-Becerra JDD, Schuster L, Dias R.   +4 more
europepmc   +1 more source

Large-scale mapping of environmental-genetic interactions illustrates the dynamic nature of cell-cycle and DNA repair regulation. [PDF]

Mol Cell
Herken BW, Wong GT, Mäkiniemi A, Lundberg E, Norman TM, Gilbert LA.   +5 more
europepmc   +1 more source

From vibrations to function: Spectroscopic detection and quantification of π-π stacking in drug-responsive protein complexes. [PDF]

Sci Adv
Altangerel N, Ocola EJ, Neuman BW, Yakovlev VV, Kuo ST, Vulupala VR, Khatua K, Zhang H, Yan X, Russell DH, Xu S, Fierke CA, Liu WR, Sokolov AV, Hemmer PR, Scully MO.   +15 more
europepmc   +1 more source

Multiomics Characterization of GCSH + Macrophages Reveals Therapeutic Vulnerabilities and Immune-Metabolic Crosstalk in Triple-Negative Breast Cancer. [PDF]

Hum Mutat
Ge J, Chen T, Ma Y, Wei S.
europepmc   +1 more source

NLRP14 modulates the activity of E3 ubiquitin ligases during the oocyte-to-embryo transition. [PDF]

Nat Commun
Liu S, Qi Q, Chi P, Jiao H, Yan L, Lu Y, Zhang R, Li J, Ju S, Han Z, Zhang Z, Liu Q, Ou G, Li J, Chen J, Wang X, Li L, Guo L, Jiao X, Hu H, Jiang Y, Deng D.   +21 more
europepmc   +1 more source

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Protein interaction maps for model organisms

Nature Reviews Molecular Cell Biology, 2001
Until recently, classical genetics and biochemistry were the main techniques used to investigate how organisms develop, reproduce, behave and age. But with the availability of complete genome sequences new approaches are emerging. Complete sets of proteins — 'proteomes' — can be predicted from genome sequences and used to characterize protein functions
Albertha J M Walhout, Marc Vidal, Walhout Albertha J M   +2 more
exaly   +3 more sources

Protein interaction maps on the fly

Nature Biotechnology, 2004
A protein interaction map for the fruit fly Drosophila melanogaster promises to facilitate functional analysis of many eukaryotic proteins.
Peter Uetz, Michael J Pankratz, Uetz Peter   +2 more
exaly   +4 more sources

Mapping Protein: Carbohydrate Interactions

Current Protein & Peptide Science, 2003
Many biologically important interactions occur between proteins and carbohydrates. The examination of these interactions at the atomic level is critical not only in understanding the nature of these interactions and their biological role, but also in the design of effective modulators of these interactions.
Gerald F, Audette, Louis T J, Delbaere, Jim, Xiang   +2 more
openaire   +2 more sources