Results 261 to 270 of about 6,367,317 (393)

Analysis of protein isoforms: Can we do it better?

Proteomics, 2012
M. Stastna, J. V. Van Eyk
semanticscholar   +1 more source

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

Advanced Science, EarlyView.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha, Kyle L. MacQuarrie, Marcelo Carignano, Cody L. Dunton, Ruyi Gong, Joe Ibarra, Lucas M. Carter, Wing Shun Li, Rikkert Nap, Parambir S. Dulai, Igal Szleifer, Vadim Backman   +11 more
wiley   +1 more source

Corrigendum: C-reactive protein isoforms as prognostic markers of COVID-19 severity. [PDF]

Front Immunol
Molins B, Figueras-Roca M, Valero O, Llorens V, Romero-Vázquez S, Sibila O, Adan A, Garcia-Vidal C, Soriano A.   +8 more
europepmc   +1 more source

Structural changes in barley protein LTP1 isoforms at air-water interfaces [PDF]

, 2017
Yani Zhao, Marek Cieplak
openalex   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Truncated protein isoforms generate diversity of protein localization and function in yeast. [PDF]

Cell Syst
Higdon AL, Won NH, Brar GA.
europepmc   +1 more source

Mining Unknown Porcine Protein Isoforms by Tissue-based Map of Proteome Enhances Pig Genome Annotation. [PDF]

Genomics Proteomics Bioinformatics, 2021
Zhao P, Zheng X, Yu Y, Hou Z, Diao C, Wang H, Kang H, Ning C, Li J, Feng W, Wang W, Liu GE, Li B, Smith J, Chamba Y, Liu JF.   +15 more
europepmc   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Measuring the capacity of yeast for surface display of cell wall-anchored protein isoforms by using β-lactamase as a reporter enzyme. [PDF]

FEBS Open Bio
Martinić Cezar T, Paić A, Prekpalaj S, Teparić R, Žunar B, Stuparević I.   +5 more
europepmc   +1 more source

Multimodal detection of protein isoforms and nucleic acids from mouse pre-implantation embryos. [PDF]

Nat Protoc, 2021
Rosàs-Canyelles E, Modzelewski AJ, Geldert A, He L, Herr AE.   +4 more
europepmc   +1 more source