Results 281 to 290 of about 648,804 (352)

Computational Design and Cellular Synthesis of Two Protein Topological Isoforms: Solomon Link vs Three-Twist Knot [PDF]

Wenhao Wu, Lianjie Xu, Hua Xu, Xiaodong Su, Wenbin Zhang   +4 more
openalex   +1 more source

Protein kinase C isoform diversity in the heart

Journal of Molecular and Cellular Cardiology, 1995
S F, Steinberg, M, Goldberg, V O, Rybin
openaire   +2 more sources

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

Advanced Science, EarlyView.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha, Kyle L. MacQuarrie, Marcelo Carignano, Cody L. Dunton, Ruyi Gong, Joe Ibarra, Lucas M. Carter, Wing Shun Li, Rikkert Nap, Parambir S. Dulai, Igal Szleifer, Vadim Backman   +11 more
wiley   +1 more source

Identification and Characterization of Three Epithiospecifier Protein Isoforms in Brassica oleracea. [PDF]

Front Plant Sci, 2019
Witzel K, Abu Risha M, Albers P, Börnke F, Hanschen FS.   +4 more
europepmc   +1 more source

Positional Isoform Analysis of Pegylated Biotherapeutic Protein Using a Novel Peptide-Based Reversed-Phase Chromatography Approach

Min Wang, Yunting Chen, Jianping Zhai, Yujia Jia, Jinliang Zhang, Hailong Liu, Jingdi Wang, Jielun Cong, Junnan Liu, Xuejiao Jia, Yingwu Wang   +10 more
openalex   +1 more source

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

Advanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie, Qiuyang Zheng, Jiaming Lv, Qian Zhang, Zhiwei Cui, Shuai Huang, Wei Yu, Binyang Chen, Wanling Que, Shanpan Fu, Yuemei Xi, Jiayu Chen, Xueling Ye, Shuyi Chen, Hairong Zhao, Tetsuya Yamamoto, Hidenori Koyama, Xin Wang, Jidong Cheng   +18 more
wiley   +1 more source

Proteins encoded by human Down syndrome critical region gene 1-like 2 (DSCR1L2) mRNA and by a novel DSCR1L2 mRNA isoform interact with cardiac troponin I (TNNI3)

, 2006
Silvia Canaider, Federica Facchin, Cristiana Griffoni, Raffaella Casadei, Lorenza Vitale, Luca Lenzi, Flavia Frabetti, Pietro D’Addabbo, Paolo Carinci, Maria Zannotti, Pierluigi Strippoli   +10 more
openalex   +2 more sources

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Regression analysis of juvenile gill (G, open circle, dashed line), adductor muscle (A, grey circle, grey line), and mantle (M, black circle, black line) tissue relative protein expression for the 3 isoforms of Hsp70 versus the average of previous 2 weeks daily dissolved oxygen (DO) concentrations.

, 2015
Heather K. Patterson, Anne Boettcher, Ruth H. Carmichael   +2 more
openalex   +2 more sources